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Clormetazoline hydrochloride

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Identification
Molecular formula
C5H12Cl2NO
CAS number
3539-91-9
IUPAC name
2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide;hydrochloride
State
State

At room temperature, the compound is in a solid state. It is usually handled as a powder in laboratory settings.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.15
Boiling point (Celsius)
314.70
Boiling point (Kelvin)
587.90
General information
Molecular weight
211.12g/mol
Molar mass
211.1300g/mol
Density
1.1200g/cm3
Appearence

Clormetazoline hydrochloride typically appears as a white to off-white crystalline powder. It is soluble in water, indicating its use in various pharmaceutical formulations.

Comment on solubility

Solubility of 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide; hydrochloride

The compound 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide; hydrochloride presents interesting solubility characteristics that are vital for its application in various chemical processes.

This compound is typically soluble in:

  • Water: The presence of the hydrochloride group enhances its solubility in aqueous environments, making it a good candidate for formulations that require a stable solution.
  • Polar solvents: Its polarity allows for solvation in solvents like ethanol and methanol, which can facilitate its use in organic reactions.

However, factors influencing its solubility include:

  1. Temperature: Higher temperatures often increase solubility, allowing more of the compound to dissolve.
  2. pH levels: The solubility can be affected by the pH of the solution, given the basic character of amines.
  3. Ionic strength: In a saline or ionic environment, the solubility might be altered due to interactions with other ions.

In summary, the solubility of 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide; hydrochloride is largely influenced by its structure and environmental conditions. It is critical to tailor these conditions for optimal dissolving behavior, ensuring effective usage in chemical applications.

Interesting facts

Interesting Facts about 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide; hydrochloride

2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide; hydrochloride is a fascinating compound with several noteworthy characteristics:

  • Medicinal Uses: This compound is studied for potential applications in the medical field, particularly as an intermediate in the synthesis of pharmaceuticals, especially antitumor agents.
  • Synthetic Pathways: Scientists often explore various synthetic pathways to produce this compound efficiently, making it an interesting subject of research for organic chemists.
  • Chlorinated Compounds: As a chlorinated amine, its reactivity can be affected by the presence of chlorine atoms, leading to varied interactions in different chemical environments.
  • Oxidation State: The inclusion of the oxide group indicates that it possesses unique properties related to electron transfer processes and can influence its behavior in chemical reactions.
  • Structure-Activity Relationship (SAR): The modifications in its molecular structure compared to other amines can provide insights into how similar compounds exhibit biological activity, making it essential for medicinal chemistry research.

Overall, 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide; hydrochloride is not only intriguing due to its chemical structure but also showcases the intricate relationship between chemical properties and biological functions. As one scientist put it, "The beauty of chemistry lies in the connections we uncover between structure and function." Studying such compounds opens the door to groundbreaking discoveries and applications in various fields.

Synonyms
Nitromin
Mitomen
Mustron
Ossiamina
Ossichlorin
302-70-5
Nitromin hydrochloride
NITROGEN MUSTARD N-OXIDE HYDROCHLORIDE
MBAO hydrochloride
Mechlorethamine oxide hydrochloride
HN2 oxide hydrochloride
N-Oxyd-Lost
XA 2
Nitrogen mustard oxide hydrochloride
SK-598
Methyldi(2-chloroethyl)amine N-oxide hydrochloride
Nitrogen mustard oxide
N-Methylbis(2-chloroethyl)amine N-oxide hydrochloride
2,2'-Dichloro-N-methyldiethylamine N-oxide hydrochloride
N-Methyl-2,2'-dichlorodiethylamine N-oxide hydrochloride
2-Chloro-N-(2-chloroethyl)-N-methylethanamine-N-oxide hydrochloride
Nitrogen mustard n-oxide hydrochloride [JAN]
009L92D6OC
Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-, N-oxide, hydrochloride
2-chloro-N-(2-chloroethyl)-N-methylethanamine oxide;hydrochloride
N-Oxyd-lost-hcl
Methylbis(.beta.-chloroethyl)amine N-oxide hydrochloride
Nitrogen mustard N-oxide hydrochloride (JAN)
HSDB 5106
chlormethine N-oxide hydrochloride
Chlormethine-N-oxide hydrochloride
Nitrogen mustard N-oxide HCl
UNII-009L92D6OC
AI3-52462
HN20 hydrochloride
Methylbis(2-chloroethyl)amine N-oxide hydrochloride
Methylbis(beta-chloroethyl)amine N-oxide hydrochloride
N-Methylbis(beta-chloroethyl)amine N-oxide hydrochloride
Methyl-bis-(beta-chloraethyl)-amin-N-oxyd-hydrochlorid [German]
Chlormethine N-oxide HCl
SCHEMBL8793
Methyl-bis-(beta-chloraethyl)-amin-N-oxyd-hydrochlorid
DTXSID0023375
CHEBI:31913
SYNHCENRCUAUNM-UHFFFAOYSA-N
Ethanamine, N-oxide, hydrochloride
Diethylamine, 2,2'-dichloro-N-methyl-, N-oxide, hydrochloride
Nitrogen mustard N-oxide, hydrochloride
WLN: G2KO & 1 & 2G & GH
D01493
MECHLORETHAMINE OXIDE HYDROCHLORIDE [MI]
bis(2-chloroethyl)methylamine oxide hydrochloride
CHLORMETHINE OXIDE HYDROCHLORIDE [WHO-DD]
NITROGEN MUSTARD N-OXIDE HYDROCHLORIDE [HSDB]
Q27231340
Diethylamine,2'-dichloro-N-methyl-, N-oxide, hydrochloride
METHYLBIS(.BETA.-CHLOROETHYL)AMINE OXIDE HYDROCHLORIDE