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Anthranilic acid

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Identification
Molecular formula
C8H7NO3
CAS number
118-92-3
IUPAC name
2-carbamoylbenzoic acid
State
State

Anthranilic acid is solid at room temperature. It is usually available in crystalline form and is not volatile under normal conditions.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
383.90
Boiling point (Kelvin)
657.05
General information
Molecular weight
151.15g/mol
Molar mass
151.1530g/mol
Density
1.4430g/cm3
Appearence

Anthranilic acid appears as a white to slightly yellow crystalline powder. It can also form dendritic crystals or can resemble white or light yellowish needles. Due to exposure to air and light, it may acquire a yellowish hue over time.

Comment on solubility

Solubility of 2-Carbamoylbenzoic Acid

2-Carbamoylbenzoic acid, also referred to by its systematic name, exhibits noteworthy solubility characteristics that are influenced by its molecular structure. Typically, this compound is considered to be:

  • Moderately soluble in water, primarily due to the presence of the amide and carboxylic acid functional groups, which can facilitate hydrogen bonding.
  • Soluble in organic solvents such as ethanol and acetone, which are capable of engaging in appropriate intermolecular interactions with the compound.
  • Insoluble in non-polar solvents, given that azole compounds generally favor polarity in their interactions.

To summarize, the solubility of 2-carbamoylbenzoic acid can be categorized as follows:

  1. Water: Moderate solubility
  2. Ethanol: Soluble
  3. Acetone: Soluble
  4. Non-polar Solvents: Insoluble

This solubility profile demonstrates the importance of both functional groups and molecular interactions in determining the behavior of 2-carbamoylbenzoic acid in various environments.

Interesting facts

Interesting Facts About 2-Carbamoylbenzoic Acid

2-Carbamoylbenzoic acid, also known as anthranilic acid, is a fascinating compound that plays a significant role in the realm of organic chemistry and biochemistry. This aromatic compound features a carboxylic acid group attached to an anthranilic moiety, making it particularly interesting for various applications.

Key Points to Note:

  • Biological Significance: This compound is not just a lab curiosity; it is a naturally occurring amino acid precursor involved in the synthesis of the essential amino acid tryptophan.
  • Pharmaceutical Relevance: 2-Carbamoylbenzoic acid has been studied for its potential anti-inflammatory and analgesic properties, making it a subject of research in drug development.
  • Flavor and Fragrance: It is known to impart a pleasant scent, making it useful in the fragrance industry and also contributing to the unique flavor profile of various foods.
  • Industrial Applications: Beyond its biological roles, it can be utilized in the synthesis of dyes and pigments, adding value to its chemical versatility.

As a compound of interest, 2-carbamoylbenzoic acid also highlights the intricate connections between chemistry and biology. Its involvement in metabolic pathways showcases the beauty of biochemical processes, where simple compounds can lead to complex outcomes. Its availability and relative ease of synthesis make it a valuable tool in both laboratory research and industrial applications.

In conclusion, 2-carbamoylbenzoic acid stands as a testament to the multifaceted nature of chemical compounds, bridging the gap between natural processes and modern application. As scientists continue to explore its properties, the potential for new discoveries remains vast.

Synonyms
PHTHALAMIC ACID
2-carbamoylbenzoic acid
88-97-1
Phthalamidic acid
Phthalamide acid
Phthalic acid monoamide
Phthalic monoamide
o-Carbamoylbenzoic acid
Benzoic acid, 2-(aminocarbonyl)-
Benzoic acid, o-carbamoyl-
2-(Aminocarbonyl)benzoic acid
UNII-V344H4PF3Y
V344H4PF3Y
NSC 5344
NSC-5344
EINECS 201-871-1
MFCD00025476
AI3-26413
DTXSID0058980
CHEBI:50736
NSC 5344; Phthalamide acid; Phthalamidic acid
phthalicimide
folpet TP3
2-Carboxybenzamide
Phthalamic acid, 97%
Maybridge1_007029
SCHEMBL8771
Oprea1_837523
2-(Aminocarbonyl)-benzoic acid
DTXCID6048628
HMS561H11
NSC5344
AKOS002310261
FS-1558
SB75814
FP175106
SY050056
DB-057112
CS-0034611
NS00014427
P0282
D70388
EN300-223398
Q27122212
F3048-0212
KLW