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2-bromo-1-(4-methoxyphenyl)ethanone

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Identification
Molecular formula
C9H9BrO2
CAS number
2632-13-5
IUPAC name
2-bromo-1-(4-methoxyphenyl)ethanone
State
State

At room temperature, 2-bromo-1-(4-methoxyphenyl)ethanone is typically found in a solid state. Its crystalline form makes it stable under standard atmospheric conditions, but it should be handled carefully to avoid any contact with moisture or heat that could transition it to a liquid or gas form as temperatures change.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.15
Boiling point (Celsius)
282.50
Boiling point (Kelvin)
555.65
General information
Molecular weight
229.07g/mol
Molar mass
229.0490g/mol
Density
1.5060g/cm3
Appearence

2-bromo-1-(4-methoxyphenyl)ethanone typically appears as a solid crystalline substance. It is white to off-white in color, and its form can range from powders to crystalline granules. The appearance may vary slightly depending on purity and handling, but it is generally consistent within these descriptions.

Comment on solubility

Solubility of 2-bromo-1-(4-methoxyphenyl)ethanone (C9H9BrO2)

The solubility of 2-bromo-1-(4-methoxyphenyl)ethanone is influenced by various factors due to its unique chemical structure. This compound is characterized by the presence of both bromine and a methoxy group, which can affect its interaction with solvents.

General Solubility Characteristics:

  • Polarity: The presence of polar functional groups generally increases the solubility in polar solvents, while the bromine atom may contribute to hydrophobic characteristics.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents such as ethanol and acetone, rather than in water due to its hydrophobic regions.
  • Temperature Influence: Solubility may increase with temperature, a common phenomenon for many organic compounds, allowing for greater molecular mobility.

In practical terms, experiments may reveal varying solubility rates depending on the solvent choice, temperature, and concentration. As with many aromatic compounds, careful consideration should be given to the solvent system for effective applications.


Understanding solubility not only aids in practical applications but also provides insights into the compound's reactivity and potential interactions in various chemical environments.

Interesting facts

Interesting Facts about 2-Bromo-1-(4-methoxyphenyl)ethanone

2-Bromo-1-(4-methoxyphenyl)ethanone is a compound that showcases the fascinating intersection of organic synthesis and medicinal chemistry. As a halogenated ketone, it possesses a unique structure that allows for a variety of applications and reactivities. Here are some intriguing aspects of this compound:

  • Medicinal Relevance: This compound can serve as a key intermediate in the synthesis of pharmaceutical agents. The presence of the bromine atom often enhances biological activity, making it a point of interest in drug development.
  • Substituent Effects: The methoxy group (-OCH3) attached to the benzene ring significantly affects the electronic properties of the compound, allowing for fine-tuned reactivity in further chemical reactions.
  • Versatile Synthesis: The synthetic routes to obtain this compound may involve methods such as nucleophilic substitution or electrophilic aromatic substitution, providing chemists with a toolkit for creative synthesis.
  • Research Focus: In the realm of organic chemistry, compounds like 2-bromo-1-(4-methoxyphenyl)ethanone can be pivotal in research focusing on developing more effective therapeutic agents, particularly in the treatment of various diseases where brominated compounds have shown promise.

As noted by one chemical researcher, “The incorporation of bromine into organic molecules opens new pathways to unexplored chemical space, exemplifying innovation in drug design.” This highlights the significant role compounds such as 2-bromo-1-(4-methoxyphenyl)ethanone play in advancing scientific knowledge and application.

Overall, the study of 2-bromo-1-(4-methoxyphenyl)ethanone not only deepens our understanding of chemical properties but also emphasizes the ongoing quest to discover new therapeutic solutions within the field of medicinal chemistry.

Synonyms
2632-13-5
2-Bromo-4'-methoxyacetophenone
2-Bromo-1-(4-methoxyphenyl)ethanone
Ethanone, 2-bromo-1-(4-methoxyphenyl)-
p-Methoxyphenacyl bromide
4-Methoxyphenacyl bromide
2-bromo-1-(4-methoxyphenyl)ethan-1-one
PTP inhibitor 1
PTP Inhibitor II
4'-Methoxyphenacyl bromide
Bromomethyl 4-methoxyphenyl ketone
MFCD00000201
PV5M69J53H
EINECS 220-118-8
NSC-129010
CHEMBL103009
4'-Methoxy-2-bromoacetophenone
DTXSID20180934
Acetophenone, 2-bromo-4'-methoxy-
NSC 129010
2-bromo-1-(4-methoxyphenyl)-ethanone
2-Bromo-4-methoxyacetophenone
4-(Bromoacetyl)anisole
alpha-Bromo-4-methoxyacetophenone
?-Bromo-4-methoxyacetophenone
alpha-Bromo-4'-methoxyacetophenone
Halomethyl Phenyl Ketone deriv. 27
p-methoxyphenacylbromide
4-methoxyphenacylbromide
4Methoxyphenacyl bromide
4-methyoxyphenacylbromide
4-methoxy-phenacyl bromide
2Bromo4'methoxyacetophenone
Bromomethyl p-anisyl ketone
4'methoxy 2bromoacetophenone
UNII-PV5M69J53H
omegaBromo4methoxyacetophenone
2-Bromo-p-methoxyacetophenone
SCHEMBL202055
p-Acetanisole; p-Acetylanisole
BDBM7879
2-Bromo-4`-methoxyacetophenone
2-Bromo-4 inverted exclamation marka-methoxyacetophenone
2-bromo-4'- methoxyacetophenone
2-bromo-4'-methoxy acetophenone
2-bromo-4'-methoxy-acetophenone
4'-methoxy-2-bromo acetophenone
alpha-Bromo-p-methoxyacetophenone
P-Methoxy-alpha-bromoacetophenone
2-Bromo-4'-methoxyacetophenone (4-Methoxyphenacyl bromide)
DTXCID60103425
omega-Bromo-4-methoxyacetophenone
Ethanone, 2bromo1(4methoxyphenyl)
.alpha.-Bromo-p-methoxyacetophenone
.omega.-Bromo-p-methoxyacetophenone
STR00973
.alpha.-Bromo-4-methoxyacetophenone
.omega.-Bromo-4-methoxyacetophenone
HSCI1_000017
NSC129010
s3678
STK802131
.alpha.-Bromo-4'-methoxyacetophenone
.omega.-Bromo-4'-methoxyacetophenone
AKOS000120889
2-Bromo-1-(4-methoxy-phenyl)ethanone
2-Bromo-4'-methoxyacetophenone, 97%
AC-2404
CCG-266786
CS-W014194
HY-W013478
NSC 129010;4-(Bromoacetyl)anisole
2-(4-Methoxyphenyl)-2-oxoethyl bromide
2-Bromo-1-(4-methoxy-phenyl)-ethanone
2-Bromo-4'-methoxyacetophenone, Pract.
2-bromo-1-(4'-methoxy-phenyl)-ethanone
2-Bromo-1-(4-methoxyphenyl)-1-ethanone
2-bromo-1-[4-(methyloxy)phenyl]ethanone
BP-11352
1-(4'-methoxyphenyl)-2-bromo-1-ethanone
DB-020578
M1004
NS00028088
EN300-21406
A16142
doi:10.14272/XQJAHBHCLXUGEP-UHFFFAOYSA-N.1
F3139-2825
Z104496012
220-118-8