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4'-Hydroxyacetophenone

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Identification
Molecular formula
C8H7BrO2
CAS number
5728-36-1
IUPAC name
2-bromo-1-(4-hydroxyphenyl)ethanone
State
State

At room temperature, 2-Bromo-1-(4-hydroxyphenyl)ethanone is typically found in a solid-state.

Melting point (Celsius)
87.00
Melting point (Kelvin)
360.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
199.05g/mol
Molar mass
199.0250g/mol
Density
1.4880g/cm3
Appearence

2-Bromo-1-(4-hydroxyphenyl)ethanone appears as a white to off-white crystalline powder. It is fairly stable under standard temperature and pressure conditions.

Comment on solubility

Solubility of 2-bromo-1-(4-hydroxyphenyl)ethanone (C8H7BrO2)

The solubility of 2-bromo-1-(4-hydroxyphenyl)ethanone, a compound characterized by its bromine and hydroxyl functional groups, offers intriguing insights into its interactions with various solvents. Understanding its solubility is essential for applications in pharmaceuticals and organic synthesis.

Solubility Characteristics

In general, the solubility of this compound can be influenced by:

  • Polarity: The presence of polar groups, such as the hydroxyl group, suggests potential solubility in polar solvents like water and alcohols.
  • Hydrogen Bonding: The hydroxyl group can engage in hydrogen bonding, likely enhancing solubility in alcohols and other polar solvents.
  • Temperature: Like many organic compounds, solubility may increase with temperature, indicating that heating the solvent could facilitate the dissolution process.

However, it is essential to note that:

  • Low solubility may be observed in non-polar solvents due to the substantial bromine atom contributing to the overall non-polar character.
  • Crystallization can occur when attempting to dissolve in less compatible solvents, suggesting a need for careful solvent selection in experimental applications.

In conclusion, while 2-bromo-1-(4-hydroxyphenyl)ethanone exhibits a degree of solubility in polar environments, the specific conditions and choice of solvent play a crucial role in ensuring effective dissolution.

Interesting facts

Exploring 2-bromo-1-(4-hydroxyphenyl)ethanone

2-bromo-1-(4-hydroxyphenyl)ethanone, with its intriguing structure, is a compound that captures the interest of chemists for several reasons. Known for its versatile chemical properties, this compound presents opportunities in various fields including medicinal chemistry and material science.

Notable Characteristics:

  • Phenolic Component: The presence of the 4-hydroxyphenyl group enhances the compound's potential for antioxidant activity, making it a subject of investigation in pharmacological studies.
  • Bromo Substitution: The introduction of bromine in the molecule contributes to the reactivity of this compound, enabling further functionalization which could lead to the development of new derivatives.
  • Biological Relevance: Compounds similar to 2-bromo-1-(4-hydroxyphenyl)ethanone have been explored for their antibacterial and antifungal properties, indicating a promising avenue for drug development.
  • Applications in Dyes and Polymers: With its structural motifs, this compound may serve as a precursor in synthesizing dyes and could also play a role in the production of polymers with desirable characteristics.

In summary, 2-bromo-1-(4-hydroxyphenyl)ethanone is a compound that exemplifies the connection between structural chemistry and potential biomedical applications. Its versatility makes it a fascinating subject for ongoing research, inspiring scientists to uncover its full range of properties and applications. As the renowned chemist Linus Pauling once stated, "The science of chemistry is the study of the nature of matter." With compounds like this, we continue to expand our understanding of what that nature entails.

Synonyms
2-BROMO-4'-HYDROXYACETOPHENONE
2491-38-5
2-bromo-1-(4-hydroxyphenyl)ethanone
2-Bromo-4-hydroxyacetophenone
Ethanone, 2-bromo-1-(4-hydroxyphenyl)-
4-Hydroxyphenacyl bromide
2-Bromo-1-(4-hydroxyphenyl)ethan-1-one
Busan 90
ptp inhibitor i
Caswell No. 115
2-Bromo-4/'-hydroxyacetophenone
alpha-Bromo-4-hydroxyacetophenone
Acetophenone, 2-bromo-4'-hydroxy-
168693-83-2
EINECS 219-655-0
6H0QU4I6BA
1-(4-Hydroxyphenyl)-2-bromoethanone
EPA Pesticide Chemical Code 008707
BRN 1865388
DTXSID4034576
CHEMBL102952
DTXCID2014576
4-08-00-00351 (Beilstein Handbook Reference)
2-Bromo-1-(4-hydroxy-phenyl)-ethanone
HYDROXYPHENYL)-2-BROMOETHANONE, 1-(4-
4-(Bromoacetyl)phenol
UNII-6H0QU4I6BA
4'-HYDROXYPHENACYL BROMIDE
4-bromoacetylphenol
MFCD00072424
Busan 93
p-hydroxyphenacyl bromide
Busan 1130
2Bromo4'hydroxyacetophenone
4-HBE
SCHEMBL79354
Acetophenone, 2bromo4'hydroxy
1(4Hydroxyphenyl)2bromoethanone
2-Bromo-4`-Hydroxyacetophenone
alpha-bromo-p-hydroxyacetophenone
alpha bromo-4-hydroxyacetophenone
2-Bromo-4\'-hydroxyacetophenone
2Bromo1(4hydroxyphenyl)ethan1one
Ethanone, 2bromo1(4hydroxyphenyl)
Tox21_301941
BDBM50119687
HSCI1_000019
s3696
STL387803
AKOS015836074
2-Bromo-1-(4-hydroxyphenyl)-ethanone
CCG-266683
CS-W002314
FB16431
GS-3432
HY-W002314
NCGC00255298-01
2-bromo-1-(4-hydroxyphenyl)-ethan-1-one
CAS-2491-38-5
2-bromo-4'-hydroxyacetophenone, AldrichCPR
B4115
NS00008843
EN300-96334
2-Bromo-4'-hydroxyacetophenone, analytical standard
Q27264894
Z1269233792