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Bromodiphenhydramine

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Identification
Molecular formula
C17H20BrNO2
CAS number
26655-82-3
IUPAC name
2-bromo-1-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]ethanone
State
State

At room temperature, Bromodiphenhydramine is usually a solid. It can be manipulated into various pharmaceutical forms for use in medications.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
372.28g/mol
Molar mass
372.2820g/mol
Density
0.4350g/cm3
Appearence

Bromodiphenhydramine typically appears as a crystalline solid. The crystals are usually colorless or white and may have a faint odor.

Comment on solubility

Solubility of 2-bromo-1-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]ethanone

The solubility of 2-bromo-1-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]ethanone can be described as follows:

  • Polar and Non-Polar Characteristics: This compound contains both polar and non-polar groups, which may affect its solubility in various solvents.
  • Solvent Compatibility:
    • Water: Due to the presence of a hydroxy (-OH) group, the compound may exhibit some level of solubility in water, although steric hindrance from the bulky diphenyl methyl group might limit this.
    • Organic Solvents: It may have better solubility in organic solvents such as ethanol or acetonitrile, which can accommodate its non-polar regions more effectively.
  • Temperature Effects: Like many organic compounds, the solubility can increase with temperature, potentially allowing for better dissolution in a heated solvent.
  • Concentration Considerations: At higher concentrations, solubility may reach a saturation point, where the compound no longer dissolves effectively.

In summary, while 2-bromo-1-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]ethanone has the potential for solubility in both polar and non-polar solvents, its overall solubility will largely depend on the specific solvent environment and conditions.

Interesting facts

Interesting Facts about 2-bromo-1-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]ethanone

2-bromo-1-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]ethanone, commonly referred to in research contexts, is a fascinating compound that has attracted the attention of many chemists due to its unique structure and potential applications. Here are some interesting aspects of this compound:

  • Chemical Structure: Analyzing the molecular architecture reveals a piperidine ring, a component that significantly influences the biological activity of many pharmaceutical agents.
  • Bioactive Properties: Compounds similar to this one have been studied for their ability to interact with various biological targets, showcasing potential as therapeutic agents.
  • Utility in Medicinal Chemistry: The incorporation of a bromine atom highlights its possible use in medicinal chemistry as a starting point for the synthesis of various analogs aimed at enhancing biological efficacy.
  • Research Applications: This compound may serve as a useful tool in pharmacological studies, providing insights into drug design and the development of novel medications.
  • Synthetic Pathways: The synthetic methods utilized to create this compound can vary; understanding these pathways is essential for the advancement of chemical synthesis techniques.

As with many chemical compounds, it is essential to consider both the potential benefits and the challenges associated with its use. In the world of chemistry, every compound opens a door to further discoveries and advancements. As stated by renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." Hence, compounds like 2-bromo-1-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]ethanone embody the spirit of innovation and exploration inherent in the field of chemistry.

Synonyms
KETONE, BROMOMETHYL 4-(DIPHENYLHYDROXYMETHYL)PIPERIDINO
143-84-0
BRN 1496802
1-Bromoacetyl-alpha,alpha-diphenyl-4-piperidinemethanol
4-Piperidinemethanol, 1-bromoacetyl-alpha,alpha-diphenyl-
DTXSID00162278