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Paclitaxel

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Identification
Molecular formula
C47H51NO14
CAS number
33069-62-4
IUPAC name
2-benzyl-11,26-bis(2-methylsulfanylethyl)-31-thia-3,9,12,18,24,27,32-heptazapentacyclo[27.2.1.05,9.014,18.020,24]dotriaconta-1(32),29-diene-4,10,13,19,25,28-hexone
State
State

Paclitaxel is typically a solid at room temperature. It is handled as a powder due to its crystalline nature and high molecular weight. In its pure form, it is used for various applications predominantly in the medical field.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
853.91g/mol
Molar mass
853.9070g/mol
Density
1.4500g/cm3
Appearence

Paclitaxel appears as a white to off-white crystalline powder. It is practically insoluble in water, but soluble in organic solvents such as alcohols and acetone. The compound has a complex chemical structure characterized by a large taxane ring with various functional groups attached, giving it its distinct crystalline form.

Comment on solubility

Solubility of 2-benzyl-11,26-bis(2-methylsulfanylethyl)-31-thia-3,9,12,18,24,27,32-heptazapentacyclo[27.2.1.05,9.014,18.020,24]dotriaconta-1(32),29-diene-4,10,13,19,25,28-hexone

The solubility of the compound with the chemical formula C47H51NO14 can be influenced by various factors such as structure, polarity, and intermolecular interactions. Here are some key points regarding its solubility:

  • Solvent Interactions: The presence of functional groups such as thioether and carbonyl can influence how well the compound dissolves in different solvents.
  • Polarity: Given its extensive carbon backbone and additional polar functional groups, this compound may exhibit variable solubility in polar versus nonpolar solvents.
  • Potential Solubility: It might be expected to have better solubility in organic solvents like dimethyl sulfoxide (DMSO) or ethanol rather than in water due to its complex structure.
  • Hydrogen Bonding: If the chemical structure allows for hydrogen bonding, it may enhance solubility in polar solvents.

In conclusion, the solubility of this compound is likely to be highly dependent on the solvent used and the interactions between the solvent and the compound. Understanding these interactions can provide valuable insights into the behavior of this complex molecule in various chemical environments.

Interesting facts

Interesting Facts About 2-benzyl-11,26-bis(2-methylsulfanylethyl)-31-thia-3,9,12,18,24,27,32-heptazapentacyclo[27.2.1.05,9.014,18.020,24]dotriaconta-1(32),29-diene-4,10,13,19,25,28-hexone

This fascinating compound, known for its complex structure, belongs to a unique class of organic molecules that combine multiple functionalities. Here are some engaging facts:

  • Diversity in Structure: This compound features an intricate arrangement of rings and chains, showcasing a pentacyclic system that contributes to its chemical properties and potential applications.
  • Functional Groups: The presence of both sulfanyl groups and benzyl groups allows this compound to engage in various chemical reactions, making it a valuable subject in synthetic organic chemistry.
  • Potential Applications: Compounds with such complex structures have been explored for their utility in pharmaceuticals, particularly as drug candidates targeting various diseases due to their rich chemistry.
  • Mechanistic Studies: Researchers are interested in studying how such complex molecules interact with biological systems, providing insight into molecular mechanisms and potentially leading to new therapeutic approaches.
  • Quote from Researchers: “Understanding the behavior of complex compounds opens new pathways in drug discovery and materials science.”

As a compound with a large molecular size and intricate topology, it presents unique challenges and opportunities in terms of synthesis and characterization. Continued research can unveil its full potential and applications.