Benzylpenicillin (Penicillin G) | Solubility of Things

Identification

Molecular formula

C₁₆H₁₈N₂O₄S

CAS number

61-33-6

IUPAC name

2-benzyl-11-(2-methylsulfanylethyl)-26-(2-methylsulfinylethyl)-31-thia-3,9,12,18,24,27,32-heptazapentacyclo[27.2.1.05,9.014,18.020,24]dotriaconta-1(32),29-diene-4,10,13,19,25,28-hexone

State

At room temperature, Benzylpenicillin is a solid compound, typically formulated as a mineral salt for medical use due to its crystalline nature.

Melting point (Celsius)

214.00

Melting point (Kelvin)

487.15

Boiling point (Celsius)

279.00

Boiling point (Kelvin)

552.15

General information

Molecular weight

334.39g/mol

Molar mass

334.3900g/mol

Density

1.4100g/cm³

Appearence

Benzylpenicillin, commonly known as Penicillin G, appears as a white or almost white crystalline powder. It is odorless and almost insoluble in water. It is very sparingly soluble in alcohol and ether, and slightly soluble in acetone.

Comment on solubility

Solubility of 2-benzyl-11-(2-methylsulfanylethyl)-26-(2-methylsulfinylethyl)-31-thia-3,9,12,18,24,27,32-heptazapentacyclo[27.2.1.05,9.014,18.020,24]dotriaconta-1(32),29-diene-4,10,13,19,25,28-hexone

The solubility of the compound 2-benzyl-11-(2-methylsulfanylethyl)-26-(2-methylsulfinylethyl)-31-thia-3,9,12,18,24,27,32-heptazapentacyclo[27.2.1.05,9.014,18.020,24]dotriaconta-1(32),29-diene-4,10,13,19,25,28-hexone (C₁₆H₁₈N₂O₄S) is influenced by several factors:

Polarity: The presence of polar functional groups such as -OH and -S may enhance solubility in polar solvents like water.
Hydrophobic Character: The hydrophobic benzyl and thia rings can lead to decreased solubility in aqueous environments, favoring organic solvents instead.
Temperature: Increased temperature generally improves solubility for solid compounds, making them more amenable to dissolution.
pH Levels: The solubility may also vary with changes in pH, particularly if ionizable groups are present.

In essence, the solubility of this compound is a balance between its hydrophilic and hydrophobic components, hence effectively dissolving in a specific solvent system can be challenging. It is essential to choose the appropriate solvent considering factors such as *polarity* and *temperature* to achieve optimal solubility. As noted, compounds with complex structures like this often present unique solubility characteristics, making empirical testing vital for practical applications.

Interesting facts

Interesting Facts about 2-benzyl-11-(2-methylsulfanylethyl)-26-(2-methylsulfinylethyl)-31-thia-3,9,12,18,24,27,32-heptazapentacyclo[27.2.1.05,9.014,18.020,24]dotriaconta-1(32),29-diene-4,10,13,19,25,28-hexone

The compound 2-benzyl-11-(2-methylsulfanylethyl)-26-(2-methylsulfinylethyl)-31-thia-3,9,12,18,24,27,32-heptazapentacyclo[27.2.1.05,9.014,18.020,24]dotriaconta-1(32),29-diene-4,10,13,19,25,28-hexone is a fascinating chemical structure that highlights the complexity and diversity of organic compounds. Here are some interesting aspects of this compound:

Structural Complexity: This compound features an intricate arrangement of multiple rings and functional groups, demonstrating a high level of molecular complexity.
Sulfur Atoms: The presence of sulfur in the structure not only contributes to its unique properties but also plays a crucial role in the reactivity and stability of various compounds.
Potential Biological Activity: Compounds with similar structures often exhibit interesting biological activities, making them subjects of research in pharmacology and medicinal chemistry.
Molecular Diversity: This compound illustrates the vast diversity found within organic chemistry, particularly in creating compounds with specific functionalities for targeted applications.
Research Implications: Due to its elaborate structure, this compound could open up avenues for the development of novel materials or therapeutic agents.

As noted by chemists, "The beauty of chemistry lies in the intricate relationships between structure and function." This compound exemplifies this principle, as its complex arrangement potentially correlates with unique chemical behavior and applications.

In summary, 2-benzyl-11-(2-methylsulfanylethyl)-26-(2-methylsulfinylethyl)-31-thia-3,9,12,18,24,27,32-heptazapentacyclo[27.2.1.05,9.014,18.020,24]dotriaconta-1(32),29-diene-4,10,13,19,25,28-hexone stands as a testament to the possibilities of chemical synthesis and the ongoing exploration in the field of organic chemistry.