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2-Amino-6,7-dihydroxytetralin

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Identification
Molecular formula
C10H13NO2
CAS number
130287-70-4
IUPAC name
2-aminotetralin-6,7-diol
State
State

At room temperature, 2-amino-6,7-dihydroxytetralin is typically found as a solid.

Melting point (Celsius)
197.00
Melting point (Kelvin)
470.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
167.19g/mol
Molar mass
167.1930g/mol
Density
1.3210g/cm3
Appearence

2-Amino-6,7-dihydroxytetralin typically appears as a crystalline solid. Its color can vary from white to off-white, depending on its purity and exact form. The compound is generally available as a fine powder.

Comment on solubility

Solubility of 2-aminotetralin-6,7-diol (C10H13NO2)

2-aminotetralin-6,7-diol exhibits interesting solubility characteristics due to its structural composition. Typically, the solubility of organic compounds can be influenced by factors such as polarity, hydrogen bonding capability, and molecular size.

Factors Affecting Solubility:

  • Polarity: The presence of hydroxyl (-OH) groups enhances polarity, which may increase solubility in polar solvents.
  • Hydrogen Bonding: The -OH groups can participate in hydrogen bonding, making the compound more soluble in solvents capable of forming similar interactions.
  • Molecular Size: With a moderate molecular weight of 163.22 g/mol, this compound can more easily interact with solvent molecules.

As a general observation:

  • High solubility is often found in polar solvents like water and alcohols.
  • Lower solubility may be expected in non-polar solvents such as hexane.

In summary, we can anticipate that 2-aminotetralin-6,7-diol is likely to be relatively soluble in polar solvents, due to its favorable interaction with such environments. As always, it is crucial to experimentally verify these solubility expectations for precise applications.

Interesting facts

Interesting Facts about 2-Aminotetralin-6,7-diol

2-Aminotetralin-6,7-diol is a fascinating compound that belongs to the class of organic chemicals known as diamines. This compound exhibits unique properties and has implications in various fields, particularly in medicinal chemistry. Here are some engaging facts about this intriguing molecule:

  • Structural Features: The structure of 2-aminotetralin-6,7-diol is characterized by its bicyclic framework, which is derived from a tetralin core. This structure contributes to its biological activities and the ability to interact with various biological targets.
  • Potential Therapeutic Applications: Compounds similar to 2-aminotetralin-6,7-diol have been studied for their potential in treating neurological disorders. Research indicates that they may exhibit activity in modulating neurotransmitter systems, making them subjects of interest in pharmacology.
  • Isoforms and Variants: The presence of multiple isomeric forms of aminotetralins allows for diverse investigation into their chemical properties and biological activities. Each variation can provide unique insights into structure-activity relationships.
  • Research Trends: The compound has drawn attention in the realm of drug design and development. As scientists prioritize compounds that can easily cross the blood-brain barrier, it sparks ongoing research into structural modifications for enhanced efficacy.
  • Synthesis Challenges: The synthesis of this compound can pose various challenges. Scientists employ different synthetic routes, and optimizing these can yield higher purity and better yield, which are crucial for further research and application.

In conclusion, 2-Aminotetralin-6,7-diol is more than just a chemical entity; it represents a potential pathway in understanding complex biological systems and drugs, showcasing the depth of research and innovation in the field of chemistry.

Synonyms
ADTN
53463-78-8
6,7-Dihydroxy-2-aminotetralin
2-Amino-6,7-dihydroxytetralin
6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol
6,7-Adtn
6-Amino-5,6,7,8-tetrahydro-2,3-naphthalenediol
2,3-Naphthalenediol, 6-amino-5,6,7,8-tetrahydro-
(+)-ADTN
ZTM7UYI7VX
CHEMBL26736
MLS002172466
6,7-Dihydroxy-3-chromanamine
UNII-ZTM7UYI7VX
SMR001254097
2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene
SR-01000075362
(+)-ADTN (aminotetralin-6,7-diol)
Biomol-NT_000003
2-aminotetralin-6,7-diol
cid_3153
Lopac0_000415
BSPBio_001023
GTPL932
KBioGR_002511
KBioSS_002519
BPBio1_001127
SCHEMBL3126243
BDBM81195
KBio2_002511
KBio2_005079
KBio2_007647
KBio3_002989
DTXSID40968175
CHEBI:230904
cid_11957526
cMAP_000069
(+/-)-ADTN
HMS1792C05
HMS1990C05
HMS3403C05
ADTN, (+/-)-
NSC826351
PDSP1_000478
PDSP1_000820
PDSP2_000476
PDSP2_000807
2-aminotetralin-6,7-diol;hydrobromide
AKOS006328808
CCG-204507
NSC-826351
SDCCGSBI-0050400.P002
(+/-)-2-amino-6,7-dihydroxytetralin
NCGC00015291-02
NCGC00015291-03
NCGC00015291-04
NCGC00015291-05
NCGC00015291-06
NCGC00015291-07
NCGC00162147-01
NCGC00162147-02
NCGC00162147-03
NCGC00162147-04
FA151667
(+/-)-6,7-DIHYDROXY-2-AMINOTETRALIN
2-AMINO-6,7-DIHYDROXYTETRALIN, (+/-)-
L000081
6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol
SR-01000075362-6
Q27074318
6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide
(+/-)-2-AMINO-6,7-DIHYDROXY-1,2,3,4-TETRAHYDRONAPHTHALENE