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2-Aminophenol

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Identification
Molecular formula
C6H7NO
CAS number
95-55-6
IUPAC name
2-aminophenol
State
State

2-Aminophenol is typically found in a solid state at room temperature.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.00
Boiling point (Celsius)
164.00
Boiling point (Kelvin)
437.00
General information
Molecular weight
109.13g/mol
Molar mass
109.1260g/mol
Density
1.3280g/cm3
Appearence

2-Aminophenol appears as a white to reddish-brown crystalline solid. Its color may vary slightly depending on the purity of the sample. When exposed to air, it can darken due to oxidation.

Comment on solubility

Solubility of 2-Aminophenol (C6H7NO)

2-Aminophenol, also known as o-aminophenol, exhibits interesting solubility characteristics that are important to consider in various applications. Its chemical structure, featuring both amino (-NH2) and hydroxyl (-OH) functional groups, contributes to its solubility in different solvents.

Key points about solubility:

  • Water Solubility: 2-Aminophenol is moderately soluble in water. This solubility is attributed to its ability to form hydrogen bonds with water molecules, enhancing its dissolution.
  • Solvent Choice: It tends to dissolve well in polar organic solvents such as ethanol and methanol. However, it is less soluble in non-polar solvents, reflecting its polar characteristics.
  • pH Influence: The solubility can be affected by pH levels. In acidic conditions, the amino group can become protonated, potentially increasing solubility, while alkaline conditions might lead to decreased solubility.

In summary, the solubility of 2-aminophenol is a nuanced topic, significantly influenced by factors such as pH and the choice of solvent. Its ability to interact with solvents through hydrogen bonding is a remarkable feature that makes it a valuable compound in various chemical processes.

Interesting facts

Interesting Facts about 2-Aminophenol

2-Aminophenol is an intriguing chemical compound that belongs to the class of aminophenols. Its unique structure features an amino group (-NH2) and a hydroxyl group (-OH) attached to a benzene ring, making it a valuable compound in various chemical applications. Below are some fascinating insights:

  • Versatile Applications: 2-Aminophenol is utilized in the synthesis of dyes, pharmaceuticals, and agrochemicals. Its derivative compounds are particularly important in the dye industry for producing colors in textiles.
  • Antioxidant Properties: This compound has been studied for its potential antioxidant properties, which could have implications for health and wellness products. Research indicates that it may help to mitigate oxidative stress.
  • Pharmaceutical Relevance: 2-Aminophenol is also a precursor in the synthesis of drugs, including those aimed at treating various conditions, demonstrating its importance in medicinal chemistry.
  • Analytical Uses: The compound can be used in chromatography and other analytical techniques to separate and identify different chemical entities due to its distinct properties.
  • Safety Considerations: As with many chemicals, it is essential to handle 2-aminophenol with care. While it offers many benefits, it can also present health risks, necessitating proper safety protocols during handling.

In summary, 2-aminophenol is not just a simple amino derivative of phenol; it plays a critical role in various scientific fields and applications. This compound exemplifies the intricate relationship between chemistry and everyday products, making it an essential subject of study for students and professionals alike.

Synonyms
2-Aminophenol
95-55-6
O-AMINOPHENOL
o-Hydroxyaniline
2-Hydroxyaniline
Phenol, 2-amino-
2-Amino-1-hydroxybenzene
Questiomycin B
Fouramine OP
2-Hydroxyanaline
Benzofur GG
Nako Yellow ga
Pelagol Grey GG
Pelagol 3GA
Nako Yellow 3GA
Phenol, o-amino-
o-Hydroxyphenylamine
2-Aminobenzenol
ortho-aminophenol
BASF ursol 3GA
Zoba 3GA
Paradone Olive Green B
1-Amino-2-hydroxybenzene
1-Hydroxy-2-aminobenzene
C.I. Oxidation Base 17
Phenol, amino-
CI Oxidation Base 17
2-amino phenol
C.I. 76520
NSC 1534
UN2512
CCRIS 4144
2-AMINO-PHENOLE
CHEBI:18112
HSDB 4246
CI 76520
2-amino-phenol
AI3-09065
EINECS 202-431-1
UNII-23RH73DZ65
2-Aminophenyl alcohol
DTXSID8024498
AMINOPHENOL, O-
NSC-1534
MFCD00007690
O-AMINOPHENOL [MI]
2-AMINOPHENOL [HSDB]
Benzene, 1-hydroxy-2-amine-
DTXCID104498
EC 202-431-1
23RH73DZ65
2-AMINOPHENOL [USP IMPURITY]
c0316
STK286021
o-Aminophenol [UN2512] [Poison]
aniline, 2-hydroxy-
NCGC00091188-01
CI-76520
MESALAZINE IMPURITY C [EP IMPURITY]
2AF
2-AMINOPHENOL (USP IMPURITY)
MESALAZINE IMPURITY C (EP IMPURITY)
oAminophenol
oHydroxyaniline
2-Aminophenol; Mesalazine Imp. C (EP); Mesalazine Impurity C
2hydroxyaniline
2aminophenol
2Hydroxyanaline
amino-phenol
Phenol, oamino
O-Amino phenol
Amino-2-phenol
Nako yellow EGA
Phenol, 2amino
oHydroxyphenylamine
2-hydroxybenzenamine
ZINC00157526
2-aminohydroxybenzene
1Amino2hydroxybenzene
1Hydroxy2aminobenzene
2Amino1hydroxybenzene
2-amino-hydroxybenzene
2-Aminophenol, 99%
WLN: ZR BQ
bmse000310
Epitope ID:128160
O-AMINOHYDROXYBENZENE
SCHEMBL24436
O-AMINOPHENOL [INCI]
MLS002454422
BIDD:GT0801
CHEMBL28319
36683_RIEDEL
EXPT00102
MSK2903
NSC1534
3-bromo-1-methyl-quinolin-2-one
HMS3039N03
2-Aminophenol, puriss., 99.5%
CS-D1201
STR00335
Tox21_200932
AKOS000119785
DB01726
FA71182
CAS-95-55-6
NCGC00091188-02
NCGC00091188-03
NCGC00258486-01
Phen-2,3,4,5-D4-OL, 6-amino-
BP-13471
SMR001372016
DB-024292
2-Aminophenol, purum, >=98.0% (HPLC)
A0335
A1106
NS00001117
2-Aminophenol 100 microg/mL in Acetonitrile
EN300-17960
C01987
D88377
2-Aminophenol, PESTANAL(R), analytical standard
Q1089204
8CFFFA6B-6ACF-4377-B782-47586CF00CCB
Z57127952
F2190-0437
Mesalazine impurity C, European Pharmacopoeia (EP) Reference Standard
2-Aminophenol (Mesalazine Impurity C - PhEur), Pharmaceutical Secondary Standard; Certified Reference Material
202-431-1