Interesting facts
Interesting Facts about 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide, commonly known in research circles, offers a diverse array of interesting properties and applications:
- Pharmacological Potential: This compound has garnered interest due to its potential therapeutic effects. Research is ongoing into its applications in treatments for various neurological and psychiatric conditions, where modulation of neurotransmitter systems is vital.
- Structure-Activity Relationship (SAR): The unique substitutions in its structure, particularly the dimethoxy phenyl group, contribute to significant variations in biological activity. Understanding these relationships is crucial in drug design and development.
- Natural Product Inspiration: The backbone of this compound features structures often found in natural products, suggesting a bioactive origin. Compounds inspired by nature have historically led to many essential pharmaceuticals.
- Chirality Considerations: With the presence of multiple chiral centers, the compound can exist in various stereoisomeric forms. This aspect highlights the importance of studying chirality and its effects on efficacy and safety in medicinal chemistry.
- Analytical Techniques: Characterizing this compound presents opportunities to employ advanced analytical techniques such as NMR and mass spectrometry, allowing chemists to unravel its intricate structure and behavior.
In summary, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide is not just a chemical entity but a gateway to understanding intricate biochemical interactions and the development of therapeutic agents. As the field of medicinal chemistry continues to evolve, this compound’s fascinating features may pave the way for innovative treatments.
Synonyms
midodrine
42794-76-3
Midodrin
Midodrina
Midodrinum
Midodrinum [INN-Latin]
Midodrina [INN-Spanish]
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide
St 1085
ProAmatine
1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol
Midodrine free base
ST-1085
DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid
UNII-6YE7PBM15H
Acetamide, 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)-
EINECS 255-945-3
6YE7PBM15H
Midodrine (INN)
CHEBI:6933
HSDB 7854
2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamid
2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethylacetamide
(RS)-N'-(beta-Hydroxy-2,5-dimethoxy-phenethyl)glycinamid
2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide
DTXSID0023321
42794-76-3 (free base)
MIDODRINE [INN]
Midodrinum (INN-Latin)
133163-28-7
Midodrina (INN-Spanish)
Midodrine [INN:BAN]
2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)acetamide
(+-)-2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide
(+/-)-2-amino-n-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide
ACETAMIDE, 2-AMINO-N-(2-(2,5-DIMETHOXYPHENYL)-2-HYDROXYETHYL)-, (+/-)-
rac-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)glycinamide
rac-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide
97476-58-9
Spectrum_001641
MIDODRINE [MI]
MIDODRINE [HSDB]
Prestwick0_000191
Prestwick1_000191
Prestwick2_000191
Prestwick3_000191
Spectrum2_001545
Spectrum3_001585
Spectrum4_000192
Spectrum5_000962
MIDODRINE [VANDF]
2-AMINO-N-[2-(2,5-DIMETHOXYPHENYL)-2-HYDROXY-ETHYL]ACETAMIDE
MIDODRINE [WHO-DD]
BSPBio_000141
BSPBio_003150
KBioGR_000763
KBioSS_002121
DivK1c_000955
SCHEMBL131436
SPBio_001390
SPBio_002062
BPBio1_000157
DTXCID903321
GTPL7240
CHEMBL1201212
SCHEMBL20996761
KBio1_000955
KBio2_002121
KBio2_004689
KBio2_007257
KBio3_002650
C01CA17
NINDS_000955
HMS3886M20
N-{2-[2,5-bis(methyloxy)phenyl]-2-hydroxyethyl}glycinamide
s5735
AKOS015967099
CS-4688
DB00211
EINECS (255-945-3)
IDI1_000955
NCGC00178238-01
NCGC00178238-02
DA-05918
FA157966
HY-12749
TS-08253
SBI-0051934.P002
AB00053715
NS00008914
C07890
D08220
AB00053715_08
EN300-25893675
Q415051
BRD-A79981887-003-05-7
BRD-A79981887-003-09-9
BRD-A79981887-003-16-4
RS)-N'-(beta-Hydroxy-2,5-dimethoxy-phenethyl)glycinamid
2-amino-n-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-acetamide
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]ethanimidic acid
(+/-)-2-AMINO-N-(.BETA.-HYDROXY-2,5-DIMETHOXYPHENETHYL)ACETAMIDE
255-945-3
Solubility of 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide
The compound 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide, with the chemical formula C12H19NO4, exhibits unique solubility characteristics due to its molecular structure.
Factors Influencing Solubility
The solubility of this compound can be influenced by several factors:
Predicted Solubility
Given these factors, it is likely that:
In conclusion, the solubility profile of 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide is a complex interplay of chemical structure and solvent interactions. Understanding these nuances aids in predicting behavior in various chemical environments.