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Abacavir

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Identification
Molecular formula
C14H18N6O
CAS number
136470-78-5
IUPAC name
2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one
State
State

The compound is typically in a solid state at room temperature, appearing as a crystalline powder.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
502.50
Boiling point (Kelvin)
775.65
General information
Molecular weight
286.34g/mol
Molar mass
286.3350g/mol
Density
1.5000g/cm3
Appearence

Abacavir typically appears as a white to slightly off-white crystalline powder.

Comment on solubility

Solubility of 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one

The solubility of 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one (C14H18N6O) is influenced by its chemical structure and functional groups. Understanding its solubility characteristics is essential for applications in pharmaceuticals and biochemistry.

Key Factors Affecting Solubility:

  • Polarity: Due to the presence of hydroxyl (-OH) groups, this compound exhibits polar characteristics, which can enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules further contributes to its solubility. The hydroxy groups can interact effectively with water molecules, resulting in higher solubility levels.
  • Molecular Weight: With a moderate molecular weight, solubility may be reasonable, but this can vary based on the specific environment in which it is dissolved.

In terms of solubility range, one might expect the following observations:

  • High solubility in aqueous environments due to hydrophilic interactions.
  • Potential reduced solubility in non-polar solvents, reflecting its hydrophilic nature.

To summarize, the solubility of 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one is predominantly favorable in aqueous solutions, attributable to its polar functional groups and capacity for hydrogen bonding. Always consider the environmental conditions when predicting solubility, as these can significantly influence the compound's behavior in various solvents.

Interesting facts

Interesting Facts about 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one

This intriguing compound has garnered attention in the fields of biochemistry and pharmaceuticals due to its structural complexity and potential biological importance. Below are some engaging insights into its characteristics:

  • Biological Role: This compound is a derivative of purine, which plays a vital role in various biological processes, including DNA and RNA synthesis. Its presence can influence cellular metabolism and signaling pathways.
  • Potential Therapeutic Applications: Researchers are investigating this compound for its potential use in treating certain medical conditions. Its structural elements suggest it may have the capacity to interact with specific biological targets.
  • Structural Features: The presence of an amino group and a hydroxymethyl group in its structure highlights its potential for forming hydrogen bonds, a critical interaction in enzyme-substrate binding and molecular recognition.
  • Synthetic Routes: The synthesis of this compound involves multi-step organic reactions, which highlight the creativity and ingenuity of synthetic chemists. This poses an opportunity for chemistry enthusiasts to explore various synthetic methodologies.
  • Research Interest: Ongoing studies focus on its pharmacological properties, signaling pathways, and long-term effects on biological systems. This aligns with the current trend in drug discovery, emphasizing the need for less toxic and more effective compounds.

As we delve deeper into the realm of chemical compounds, the exploration of 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one opens doors to potential innovations in:

  • Pharmaceutical development
  • Biochemical research
  • Molecular biology

In conclusion, this compound serves as a perfect example of how intricate chemical structures can lead to profound implications in science and medicine. Embracing such compounds fuels curiosity and drives the future of scientific exploration.