Acyclovir | Solubility of Things

Identification

Molecular formula

C₈H₁₁N₅O₃

CAS number

59277-89-3

IUPAC name

2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3H-purin-6-one

State

At room temperature, acyclovir is a solid. In its pure form, it is a crystalline powder often used in topical formulations or compressed into tablets.

Melting point (Celsius)

256.00

Melting point (Kelvin)

529.00

Boiling point (Celsius)

292.00

Boiling point (Kelvin)

565.00

General information

Molecular weight

225.21g/mol

Molar mass

225.2080g/mol

Density

1.7900g/cm³

Appearence

The compound appears as a white or almost white crystalline powder. It is odorless and is mostly used in pharmaceutical formulations.

Comment on solubility

Solubility of 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3H-purin-6-one

The solubility of 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3H-purin-6-one (C₈H₁₁N₅O₃) offers an interesting perspective on its chemical behavior in solution. Understanding solubility can provide critical insights into the compound's applications and interactions. Here are some key points to consider:

Polarity: The presence of multiple functional groups such as amino (-NH₂) and hydroxyl (-OH) in the structure contributes to the polar nature of this compound, enhancing its ability to dissolve in polar solvents.
Hydrogen Bonding: The hydroxyl groups can participate in hydrogen bonding, which typically increases solubility in water and similar solvents.
Solvent Compatibility: Excellent solubility may be expected in solvents like water and alcohols, while its solubility in non-polar solvents could be significantly lower.

As a rule of thumb, it can be said that:
“Like dissolves like.” Therefore, the polar and hydrophilic characteristics of this compound align it favorably with aqueous environments, suggesting good solubility in water.

In summary, the solubility of C₈H₁₁N₅O₃ appears to be advantageous for numerous chemical and biological applications, particularly in biological systems where aqueous solubility is crucial.

Interesting facts

Interesting Facts about 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3H-purin-6-one

2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3H-purin-6-one, often referred to in scientific literature for its complex structure and significant functions, is a fascinating compound within the field of biochemistry. This compound belongs to the purine family, which is essential for various biological processes. Here are some intriguing aspects:

Role in Metabolism: As a purine derivative, this compound is involved in crucial metabolic pathways, particularly those related to nucleic acid synthesis and energy metabolism.
Structural Complexity: Its structure includes an amino group and a unique hydroxyethyl side chain, showcasing the compound's potential for interactions with biological macromolecules.
Pharmaceutical Applications: Compounds with purine cores have been extensively researched for their potential therapeutic properties, including antiviral and anticancer activities.
Enzyme Substrate: This molecule can act as a substrate for specific enzymes, enhancing the understanding of enzymatic processes and enabling the development of targeted drugs.
Research Significance: Scientists are continually exploring this compound to uncover mechanisms of action and identify novel uses in biomedical research and drug development.

According to biochemist Hans Krebs, “Metabolism is an elaborate dance of molecules.” The presence of 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3H-purin-6-one in these metabolic pathways reflects its critical role in biological systems, making it a compound of significant interest for researchers.

In summary, the complexity and functional versatility of this purine derivative highlight its importance in both fundamental chemistry and applied sciences, bridging the gap between molecular structure and biological function.