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2-Amino-8-phosphono-octanoic acid

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Identification
Molecular formula
C8H18NO5P
CAS number
1492-51-1
IUPAC name
2-amino-8-phosphono-octanoic acid
State
State

At room temperature, 2-amino-8-phosphono-octanoic acid is in solid state, often in the form of a powder or crystalline solid.

Melting point (Celsius)
229.00
Melting point (Kelvin)
502.15
Boiling point (Celsius)
536.20
Boiling point (Kelvin)
809.35
General information
Molecular weight
235.21g/mol
Molar mass
235.2270g/mol
Density
1.4610g/cm3
Appearence

2-Amino-8-phosphono-octanoic acid is typically a white powder. It may also appear as a crystalline solid depending on its form, such as salts or hydrates.

Comment on solubility

Solubility of 2-amino-8-phosphono-octanoic acid

2-amino-8-phosphono-octanoic acid, with the chemical formula C8H18NO5P, exhibits notable solubility characteristics owing to its unique molecular structure. This compound is classified as a phosphonic acid derivative, and its solubility is largely influenced by the presence of the amino and phosphono functional groups. Here are some key points regarding its solubility:

  • Water Solubility: The hydrophilic nature of the phosphonate group enhances the water solubility of this compound, making it soluble in aqueous environments.
  • Solvent Interactions: It is likely to interact favorably with polar solvents due to its ionic and polar groups, leading to increased solubility.
  • pH Dependency: The solubility can vary with pH; at different pH levels, protonation and deprotonation of functional groups may alter its dissolution properties.
  • Comparison with Similar Compounds: Similar compounds in the phosphonic acid class often show high solubility in water, reinforcing the expectation that 2-amino-8-phosphono-octanoic acid will behave similarly.

In summary, the solubility of 2-amino-8-phosphono-octanoic acid is considerably high in water, making it versatile for various applications. As with many compounds, the overall solubility is influenced by the chemical environment and the presence of other solutes, which can further modify its behavior.

Interesting facts

Interesting Facts About 2-Amino-8-phosphono-octanoic Acid

2-Amino-8-phosphono-octanoic acid, often abbreviated as APO, is a fascinating chemical compound that belongs to the family of amino acids and phosphonates. It has attracted significant attention in various scientific fields due to its unique properties and applications.

Key Features of 2-Amino-8-phosphono-octanoic Acid:

  • Neurotransmission Modulator: This compound acts as an antagonist of the N-methyl-D-aspartate (NMDA) receptor, which plays a crucial role in excitatory neurotransmission in the brain. Its ability to modulate these receptors makes it a valuable tool in neuropharmacology.
  • Possibility in Pharmacology: Research indicates that APO may have potential therapeutic applications in treating neurological disorders, such as epilepsy and neurodegenerative diseases, by modulating synaptic transmission.
  • Synthesis Importance: The synthesis of 2-amino-8-phosphono-octanoic acid represents a significant milestone in organic chemistry due to its complex structure, which includes both amino acid and phosphonate functionalities.
  • Use in Research: This compound is frequently utilized in various experimental setups, particularly in studies focusing on calcium signaling and synaptic plasticity, highlighting its importance in furthering our understanding of neurobiology.

Furthermore, its role as a secondary messenger in cellular signaling processes underscores its significance in biochemistry. As researchers continue to explore its mechanisms and effects, 2-amino-8-phosphono-octanoic acid stands as an exemplary case of how amino acids can be intricately linked with phosphorus to influence biological systems.

In summary, the exploration of 2-amino-8-phosphono-octanoic acid not only advances our knowledge in chemical synthesis and pharmacological applications but also opens new avenues for understanding complex biochemical pathways in living organisms.

Synonyms
2-Amino-8-phosphonooctanoic acid
Octanoic acid, 2-amino-8-phosphono-
81771-84-8
2-AP8
98517-63-6
DTXSID20913229
Octanoic acid, 2-amino-8-phosphono-, (+-)-
BRN 4183969
2-amino-8-phosphono-octanoic acid
DL-2-AMINO-8-PHOSPHONOOCTANOIC ACID
DL-AP8
SCHEMBL1192036
DTXCID401342237
STL527032
AKOS030493536
AKOS037494616