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2-Amino-7-phosphonoheptanoic acid

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Identification
Molecular formula
C7H16NO5P
CAS number
32008-59-4
IUPAC name
2-amino-7-phosphono-heptanoic acid
State
State

At room temperature, 2-amino-7-phosphonoheptanoic acid is typically in a solid state.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.15
Boiling point (Celsius)
333.00
Boiling point (Kelvin)
606.15
General information
Molecular weight
211.18g/mol
Molar mass
211.1770g/mol
Density
1.3000g/cm3
Appearence

2-Amino-7-phosphonoheptanoic acid typically appears as a white, crystalline powder.

Comment on solubility

Solubility of 2-amino-7-phosphono-heptanoic acid

2-amino-7-phosphono-heptanoic acid, with the chemical formula C7H16NO5P, exhibits notable characteristics regarding its solubility. Being an amino acid derivative with a phosphonic acid group, its solubility can be influenced by several factors:

  • Polarity: The presence of both amino (-NH2) and phosphonic acid (-PO3H2) functional groups makes this compound highly polar.
  • Water Solubility: Due to its polar nature, 2-amino-7-phosphono-heptanoic acid is generally soluble in water, making it suitable for biological applications.
  • pH Dependence: The solubility of this compound may be affected by the pH of the solution, as the protonation and deprotonation of functional groups can alter its solubility profile.
  • Temperature Effects: Increasing the temperature can also enhance solubility in water, allowing for greater dissolution of the compound.

In conclusion, the solubility of 2-amino-7-phosphono-heptanoic acid can be characterized as generally high in aqueous solutions, making it a versatile compound for research and application in various chemical contexts.

Interesting facts

Interesting Facts about 2-amino-7-phosphono-heptanoic acid

2-amino-7-phosphono-heptanoic acid, often abbreviated as APH, is a fascinating compound that plays a significant role in biochemistry and molecular biology. Here are some captivating insights about this unique amino acid:

  • Structural Diversity: 2-amino-7-phosphono-heptanoic acid is characterized by its distinctive backbone, which includes both amino and phosphonate groups. This diversity in structure is crucial for the compound’s interactions within biological systems.
  • Role in Neurotransmission: As a potential neurotransmitter analogue, APH is involved in pathways associated with excitatory neurotransmission. Its phosphonate group makes it an intriguing candidate for studying glutamate receptors, which are vital for brain function and neural communication.
  • Research Applications: This compound is often utilized in research focused on neuropharmacology and neurobiology. By examining its effects, scientists can gain insights into neuronal signaling and explore therapeutic avenues for conditions such as epilepsy and neurodegenerative diseases.
  • Synthesis Challenges: The synthesis of 2-amino-7-phosphono-heptanoic acid poses challenges due to its complex structure. Researchers employ innovative synthetic methods to produce this compound, highlighting the interplay between synthetic chemistry and biological application.
  • Phosphonate Compounds: APH belongs to the broader category of phosphonate compounds, which have been extensively studied for their agricultural and medicinal properties. They are often employed as herbicides and insecticides, demonstrating the versatility of phosphorus-containing molecules in various sectors.

In summary, 2-amino-7-phosphono-heptanoic acid is more than just an amino acid; it is a compound of profound significance in both biological research and practical applications. As we continue to explore the myriad functionalities of this compound, we unlock new pathways in science that could lead to significant breakthroughs.

Synonyms
2-Amino-7-phosphonoheptanoic acid
DL-AP7
85797-13-3
78966-69-5
AP-7
DL-2-Amino-7-phosphonoheptanoic acid
UNII-P34K80CUSM
Heptanoic acid, 2-amino-7-phosphono-
BRN 3544152
NSC672105
Heptanoic acid, 2-amino-7-phosphono-, (+-)-
P34K80CUSM
(+/-)-2-Amino-7-phosphonoheptanoic acid
CHEMBL274440
(+/-)-2-AMINO-7-PHOSPHONOHEPTANOIC
DTXSID501017823
2-Amino-7-phosphono-heptanoic acid
AP-7 compound
D-(-)-2-Amino-7-phosphonoheptanoic acid
2-amino-7-phosphoheptanoic acid
Lopac0_000008
DL-AP7?
SCHEMBL154303
( inverted question mark)-AP-7
MYDMWESTDPJANS-UHFFFAOYSA-N
DTXCID101427135
HMS3260A17
KDA79713
Tox21_500008
BDBM50002363
PDSP1_000130
PDSP2_000129
AKOS005066193
(y)-2-Amino-7-phosphonoheptanoic acid
CCG-204104
LP00008
NSC-672105
SDCCGSBI-0049997.P002
(?)-2-Amino-7-phosphonoheptanoic acid
NCGC00015013-04
NCGC00015013-05
NCGC00015013-06
NCGC00024469-02
NCGC00024469-03
NCGC00260693-01
(APH)2-Amino-7-phosphono-heptanoic acid
DA-72819
NCI60_025601
(+--)-2-amino-7-phosphonoheptanoic acid
2-Amino-7-phosphono-heptanoic acid (AP7)
HY-100782
CS-0020420
EU-0100008
DL-2-Amino-7-phosphonoheptanoic acid, ~95%
A 5157
SR-01000075448
Q4653176
SR-01000075448-1
( inverted question mark)-2-Amino-7-phosphonoheptanoic acid