Skip to main content

Tetrahydrobiopterin

ADVERTISEMENT
Identification
Molecular formula
C9H15N5O2
CAS number
17528-72-2
IUPAC name
2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one
State
State

At room temperature, tetrahydrobiopterin is a solid. It is stable under standard conditions, but it has a tendency to oxidize, especially when exposed to air.

Melting point (Celsius)
310.00
Melting point (Kelvin)
583.15
Boiling point (Celsius)
274.85
Boiling point (Kelvin)
548.00
General information
Molecular weight
241.24g/mol
Molar mass
241.2440g/mol
Density
1.6928g/cm3
Appearence

Tetrahydrobiopterin is typically a colorless crystalline solid. It is hygroscopic and prone to oxidation, therefore it should be stored in a tightly sealed container, away from light and moisture.

Comment on solubility

Solubility of 2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one

The solubility of 2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one (C9H15N5O2) can be influenced by several factors, making it an intriguing compound to study in terms of its interactions with solvents. Here are some key points regarding its solubility:

  • Polarity: The presence of amino and hydroxyl groups suggests that the compound is likely polar, which could enhance its solubility in polar solvents like water.
  • Hydrogen Bonding: The functional groups can participate in hydrogen bonding, facilitating solubility in aqueous media. This characteristic may also allow it to dissolve in alcohols and other similar solvents.
  • Temperature Variations: As with many organic compounds, increasing temperature often improves solubility, allowing for increased dissolution of the compound in solvents.
  • Solvent Compatibility: It is recommended to test solubility in various organic solvents such as ethanol, methanol, and acetone to determine the best compatibility.

In summary, the solubility of 2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one is likely enhanced by its polar nature and the capability to form hydrogen bonds, making it a versatile compound in many solvent systems. However, experimental verification is essential to obtain precise solubility data in practical scenarios.

Interesting facts

Interesting Facts about 2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one

2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one is a fascinating compound with several intriguing aspects that enhance its significance in both medicinal chemistry and biochemistry. Here are some noteworthy points:

  • Structural Relation: This compound is a derivative of pteridine, a bicyclic structure that forms the backbone of many essential biological molecules, including folic acid and coenzymes.
  • Biological Activity: It has shown potential in various biological activities, including anti-inflammatory and anticancer properties, making it a subject of interest in drug development.
  • Synthesis Pathways: The synthesis of this compound involves intricate organic reactions. The ability to modify the pteridine core through simple substitutions at specific positions can lead to a variety of bioactive compounds.
  • Enzyme Interactions: The compound interacts with enzymes related to nucleotide synthesis, contributing to its role in cellular metabolism and overall health.
  • Pharmaceutical Relevance: Research around compounds similar to 2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one has led to the development of antimicrobial agents, showcasing its importance in therapeutic applications.

Quote from a researcher: "Understanding the biochemical pathways influenced by this compound could unlock new treatments for diseases that currently have limited therapeutic options."
Thus, the ongoing exploration of this compound signifies its potential role as a building block for future medicinal applications.