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2-Amino-6-methylpyrimidin-4-one

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Identification
Molecular formula
C5H7N3O
CAS number
911-98-2
IUPAC name
2-amino-6-methyl-1H-pyrimidin-4-one
State
State

At room temperature, 2-amino-6-methyl-1H-pyrimidin-4-one is in a solid state, generally presenting as a stable powder.

Melting point (Celsius)
274.00
Melting point (Kelvin)
547.15
Boiling point (Celsius)
349.00
Boiling point (Kelvin)
622.15
General information
Molecular weight
125.13g/mol
Molar mass
125.1300g/mol
Density
1.2363g/cm3
Appearence

2-Amino-6-methyl-1H-pyrimidin-4-one typically appears as a white to off-white crystalline solid. It is often characterized by its powdery form and can be identified visually by its fine granular structure.

Comment on solubility

Solubility of 2-amino-6-methyl-1H-pyrimidin-4-one (C5H7N3O)

When discussing the solubility of 2-amino-6-methyl-1H-pyrimidin-4-one, it is important to consider several key factors:

  • Polar Nature: The presence of the amino group and the carbonyl function makes this compound relatively polar, which generally enhances solubility in polar solvents, especially water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the amino group significantly contributes to its solubility in aqueous solutions. This is particularly relevant as solute-solvent interactions play a crucial role.
  • Solvent Choice: While it is expected to dissolve well in polar solvents, its solubility in non-polar solvents may be low. As a result, solubility behavior can be summarized as:
    • Highly soluble in water and alcohols.
    • Limited solubility in non-polar organic solvents.
  • Concentration Effects: As with many organic compounds, the solubility may vary with temperature. Higher temperatures often increase solubility.

In conclusion, 2-amino-6-methyl-1H-pyrimidin-4-one displays favorable solubility characteristics in polar environments, aiding its utility in various applications. As always, precise solubility data should be consulted for specific conditions and formulations.

Interesting facts

Exploring 2-Amino-6-methyl-1H-pyrimidin-4-one

2-Amino-6-methyl-1H-pyrimidin-4-one is a fascinating compound that belongs to the class of pyrimidines, which are a family of nitrogen-containing heterocycles. Here are some engaging facts and insights about this intriguing compound:

  • Biological Significance: This compound exhibits noteworthy biological relevance, as pyrimidines are fundamental building blocks in the synthesis of nucleotides, the building blocks of DNA and RNA. Its structural features allow it to participate in various biochemical pathways.
  • Pharmaceutical Potential: Due to its amino and methyl substituents, 2-amino-6-methyl-1H-pyrimidin-4-one has gained attention in medicinal chemistry. Researchers are investigating its potential in drug development, particularly in relation to its antibacterial and antiviral activities.
  • Intermediary Role: The compound is often utilized as an intermediate in organic synthesis. Its ability to undergo various reactions makes it a valuable precursor for synthesizing more complex molecules with diverse functionalities.
  • Crystallization Studies: Researchers have studied the crystallization behavior of this compound, which can provide insights into its solid-state properties and interactions. Such studies can assist in understanding its applicability in material science.
  • Structure-Activity Relationships (SAR): The compound's specific substitutions at the pyrimidine ring can be scrutinized to explore its correlation with biological activity. SAR studies are crucial for optimizing the efficacy and selectivity of potential therapeutics.

Given these points, 2-amino-6-methyl-1H-pyrimidin-4-one stands out as a compound that not only adds value to synthetic chemistry but also holds promise in the field of pharmaceuticals and biological research. Its unique structure invites continuous exploration, making it an exciting subject for both students and seasoned scientists alike.