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Tetrahydrobiopterin

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Identification
Molecular formula
C9H15N5O3
CAS number
17528-72-2
IUPAC name
2-amino-6-(hydroxymethyl)-7-methyl-7-(2-phenylethyl)-1,8-dihydropteridin-4-one
State
State

Tetrahydrobiopterin is generally in a solid state at room temperature. It is stable under normal conditions and is often used in its salt form for increased stability in pharmaceutical formulations.

Melting point (Celsius)
295.00
Melting point (Kelvin)
568.15
Boiling point (Celsius)
224.00
Boiling point (Kelvin)
497.15
General information
Molecular weight
241.25g/mol
Molar mass
241.2510g/mol
Density
1.7600g/cm3
Appearence

Tetrahydrobiopterin typically appears as a white to off-white crystalline powder. It is often administered in tablet or powder form as a pharmaceutical ingredient.

Comment on solubility

Solubility of 2-amino-6-(hydroxymethyl)-7-methyl-7-(2-phenylethyl)-1,8-dihydropteridin-4-one

The solubility of 2-amino-6-(hydroxymethyl)-7-methyl-7-(2-phenylethyl)-1,8-dihydropteridin-4-one (C9H15N5O3) can be understood by examining its structural characteristics and potential interactions with solvents. Several factors influence its solubility:

  • Polarity: The presence of hydroxyl (-OH) and amino (-NH2) groups indicates that the compound could exhibit polar characteristics, which usually enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: The capability of the hydroxymethyl and amino groups to form hydrogen bonds can significantly improve solubility in appropriate solvents, making it easier for the compound to dissolve.
  • Hydrophobic Region: The phenylethyl group adds a hydrophobic character, which might limit its solubility in polar solvents but can enhance solubility in non-polar solvents.

In summary, while predicting the exact solubility of C9H15N5O3 requires empirical data, one could surmise that:

  1. It may have good solubility in polar solvents due to its functional groups.
  2. It could demonstrate limited solubility in non-polar solvents because of the phenylethyl group's hydrophobicity.

Understanding and researching these solubility dynamics is essential for applications involving this compound, particularly in pharmacology and chemical synthesis where solubility plays a critical role.

Interesting facts

Interesting Facts about 2-Amino-6-(Hydroxymethyl)-7-Methyl-7-(2-Phenylethyl)-1,8-Dihydropteridin-4-One

This compound belongs to the family of pteridines, which are significant in various biological processes. Here are some intriguing aspects of 2-amino-6-(hydroxymethyl)-7-methyl-7-(2-phenylethyl)-1,8-dihydropteridin-4-one:

  • Biological Relevance: Pteridines play a crucial role in the biosynthesis of folate and are essential for cellular processes, impacting DNA synthesis and repair.
  • Pharmacological Potential: This compound may have potential applications in drug development, particularly in treatments targeting neurodegenerative diseases, owing to its unique structure.
  • Structural Diversity: The presence of various functional groups, such as the hydroxymethyl and phenylethyl groups, contributes to the compound's chemical reactivity and biological activity.
  • Investigative Research: Scientists are exploring the structural analogs of this compound to understand its interaction with biological macromolecules and possible therapeutic uses.
  • Potential Antioxidant Activity: Some studies suggest that pteridine derivatives may exhibit antioxidant properties, which could help in protecting cells from oxidative stress.

In summary, 2-amino-6-(hydroxymethyl)-7-methyl-7-(2-phenylethyl)-1,8-dihydropteridin-4-one stands out for its diverse chemical structure and potential implications in biological sciences, particularly in pharmacology and medicinal chemistry.