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Diazoacetylglycine

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Identification
Molecular formula
C4H6N4O3
CAS number
119-42-6
IUPAC name
2-amino-6-diazo-5-oxo-hexanoic acid
State
State

At room temperature, it is a solid.

Melting point (Celsius)
127.00
Melting point (Kelvin)
400.15
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.15
General information
Molecular weight
157.11g/mol
Molar mass
157.1330g/mol
Density
1.4040g/cm3
Appearence

A crystalline solid that is typically light orange to yellow in appearance.

Comment on solubility

Solubility of 2-amino-6-diazo-5-oxo-hexanoic acid

2-amino-6-diazo-5-oxo-hexanoic acid, with the chemical formula C4H6N4O3, exhibits unique solubility characteristics due to its structural components. This compound contains both amino and carboxylic acid functional groups, which play a crucial role in determining its solubility behavior.

Key Points on Solubility:

  • Polar nature: The presence of the amino (–NH2) and carboxylic (–COOH) functional groups enhances its polarity, allowing it to interact favorably with polar solvents, notably water.
  • Water solubility: It is expected to be soluble in water owing to hydrogen bonding capabilities, which enable effective solvation.
  • Organic solvent compatibility: On the other hand, its solubility in organic solvents may be limited due to its polar nature; non-polar solvents would likely show poor solubility for this compound.
  • pH influence: The solubility may vary with changes in pH; amine groups can be protonated in acidic conditions, potentially increasing solubility.

In summary, the solubility of 2-amino-6-diazo-5-oxo-hexanoic acid is primarily influenced by its functional groups and the nature of the solvent. As stated, "like dissolves like," hence its solubility is much greater in polar solvents compared to non-polar ones.

Interesting facts

Exploring 2-amino-6-diazo-5-oxo-hexanoic acid

2-amino-6-diazo-5-oxo-hexanoic acid, often referred to in the scientific community for its intriguing molecular structure and biochemical significance, is a compound that showcases several fascinating properties.

Key Features:

  • Diazo Group: This compound features a diazo group (-N=N-), which is known for its reactivity and the role it plays in various chemical reactions, such as coupling reactions in organic synthesis.
  • Diverse Applications: Its structure and functional groups make it a candidate for applications in pharmaceuticals and biochemistry, particularly in the synthesis of novel compounds.
  • Biochemical Interest: The compound is related to amino acids, components critical for protein synthesis, and this connection has spurred research into its biological effects and potential medicinal uses.

Interesting Insights:

As a chemistry student or scientist, one might find it stimulating to examine how the presence of both amino and oxo groups can influence the reactivity of a compound. As noted by researchers, “the diazo functionality allows for versatile reactions, opening doors to innovative synthesis pathways.”

Furthermore, compounds like 2-amino-6-diazo-5-oxo-hexanoic acid demonstrate the intricate relationship between structure and reactivity in organic chemistry, making them subjects of ongoing research and inquiry. Studying such compounds enhances our understanding of both fundamental and applied chemistry.

Synonyms
6-Diazo-5-oxo-norleucine
2-Amino-6-diazo-5-oxohexanoic acid
764-17-0
Norleucine, 6-diazo-5-oxo-
LOS90IK8XH
H-6-Diazo-5-oxo-D-Nle-OH
H-6-Diazo-5-oxo-Nle-OH
NSC7365
Diazooxonorleucin
D-DON;H-D-Glu(diazomethylketone)-OH;6-Diazo-5-oxo-D-2-aminohexanoic acid
L-DON;H-Glu(diazomethylketone)-OH;6-Diazo-5-oxo-L-2-aminohexanoic acid
DL-Diazooxonorleucine
UNII-LOS90IK8XH
CHEMBL1651883
SCHEMBL23802545
CHEBI:232155
BCP32099
6-DIAZO-5-OXO-DL-NORLEUCINE
AKOS022505117
6-(15-diazenylidene)-5-oxonorleucine
SY264659
(2S)-2-amino-6-diazo-5-oxohexanoic acid;L-Nle(6-Diazo-5-oxo)-OH