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Glutamic acid 5-amide

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Identification
Molecular formula
C6H12N2O3
CAS number
1477-69-4
IUPAC name
2-amino-5-(methylamino)-5-oxo-pentanoic acid
State
State

At room temperature, 2-amino-5-(methylamino)-5-oxo-pentanoic acid remains in a solid state, appearing granular or powdery. It is stable under normal conditions and does not vaporize easily.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
351.00
Boiling point (Kelvin)
624.15
General information
Molecular weight
146.15g/mol
Molar mass
146.1450g/mol
Density
1.4608g/cm3
Appearence

2-Amino-5-(methylamino)-5-oxo-pentanoic acid, commonly known as Glutamic acid 5-amide, typically appears as a white crystalline powder. It is unable to dissolve in ether but is soluble in water, allowing it to interact readily in aqueous solutions.

Comment on solubility

Solubility of 2-Amino-5-(methylamino)-5-oxo-pentanoic acid (C6H12N2O3)

The solubility of 2-amino-5-(methylamino)-5-oxo-pentanoic acid poses intriguing characteristics primarily due to its structural components. This compound features both amine and carboxylic acid functional groups, which can significantly influence its solubility in various solvents.

Here are some key points regarding its solubility:

  • In Water: The presence of ionizable groups in the molecule suggests that it may exhibit good solubility in water, particularly at physiological pH levels where the compound can exist in a charged form.
  • In Organic Solvents: Its solubility in non-polar organic solvents may be limited due to the polar nature of its functional groups, which favors interactions with polar solvents over non-polar ones.
  • pH Dependence: The solubility is likely to be pH-dependent; changes in pH can alter the charge state of the molecule, thereby affecting its solubility profile.

In summary, while 2-amino-5-(methylamino)-5-oxo-pentanoic acid may demonstrate substantial solubility in polar solvents, particularly water, its behavior in organic solvents will likely be minimal. Understanding these solubility properties is paramount for applications in fields such as pharmaceuticals and biochemistry.

Interesting facts

Interesting Facts About 2-amino-5-(methylamino)-5-oxo-pentanoic acid

2-amino-5-(methylamino)-5-oxo-pentanoic acid, also known as MAP (methylamino pentanoic acid), is a fascinating compound that plays a significant role in the biochemical world.

Key Characteristics:

  • Amino Acid Analog: MAP is an analog of natural amino acids, meaning it shares similar structural elements with them. This can influence its behavior in biological systems.
  • Metabolic Pathways: Because of its structure, MAP may participate in various metabolic processes which can be significant for both health and disease.
  • Potential Applications: Researchers are exploring MAP's potential in fields such as drug development, nutrition, and biochemistry, highlighting its versatility.

Biochemical Significance:

The presence of amino groups in MAP allows it to interact with enzymes and other biomolecules, significantly impacting protein synthesis and enzymatic reactions. Its unique structural properties can make it a valuable tool in studying enzyme mechanisms or mitigating metabolic disorders.

Notable Research:

Studies have suggested that compounds similar to MAP could be used in therapeutic applications:

  • Potential treatment for certain metabolic diseases.
  • As a precursor in the synthesis of more complex compounds.

In summary, 2-amino-5-(methylamino)-5-oxo-pentanoic acid is more than just a chemical formula; it's a key player in the intricate dance of biochemistry, opening doors to exciting research and potential innovations. As scientists continue to unravel its mysteries, MAP’s true capabilities may one day transform our understanding of amino acids and their roles in biological systems.

Synonyms
4703-52-0
2-amino-5-(methylamino)-5-oxopentanoic acid
2-amino-4-(methylcarbamoyl)butanoic acid
MFCD20640839
2-Amino-5-(methylamino)-5-oxopentanoicAcid
d,l-n5-methylglutamine
SCHEMBL8138
ONXPDKGXOOORHB-UHFFFAOYSA-N
ALBB-031739
NSC21552
AC6186
NSC-21552
AKOS022636058
N-Methylglutamine (H-DL-Gln(Me)-OH)
LS-11551
SY250931