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Citrulline

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Identification
Molecular formula
C6H13N3O3
CAS number
372-75-8
IUPAC name
2-amino-5-[[amino(dimethylamino)methylene]amino]pentanoic acid
State
State

At room temperature, citrulline is in a solid state.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
441.10
Boiling point (Kelvin)
714.30
General information
Molecular weight
175.19g/mol
Molar mass
175.1930g/mol
Density
1.4158g/cm3
Appearence

Citrulline is a white, crystalline powder.

Comment on solubility

Solubility of 2-amino-5-[[amino(dimethylamino)methylene]amino]pentanoic acid

The compound 2-amino-5-[[amino(dimethylamino)methylene]amino]pentanoic acid (C6H13N3O3), also known as a derivative of amino acids, exhibits interesting solubility properties largely due to its multiple amine functional groups and a carboxylic acid group. These features play a crucial role in its interactions with solvents.

When considering the solubility of this compound, it is essential to recognize the following key points:

  • Polarity: The presence of hydrophilic (water-attracting) functional groups increases the overall polarity of the molecule.
  • Hydrogen bonding: The potential for hydrogen bonding with water enhances its solubility in aqueous solutions.
  • pH dependence: The solubility can vary significantly with pH levels, particularly due to the ionizable groups that can gain or lose protons.
  • Solvent specificity: While it is soluble in water, its solubility may differ in organic solvents where competitive interactions are at play.

In summary, this compound is expected to have good solubility in water owing to its polar nature and the ability to form hydrogen bonds. As noted, "solubility behavior can be quite complex, dependent on both the structure of the solute and the nature of the solvent." Thus, in practical applications, it would be wise to test solubility under various conditions for optimal use.

Interesting facts

2-Amino-5-[[amino(dimethylamino)methylene]amino]pentanoic acid

2-Amino-5-[[amino(dimethylamino)methylene]amino]pentanoic acid is a fascinating compound often examined in the realm of biochemical research and pharmaceutical applications. Here are some captivating aspects of this compound:

  • Complex Structure: This compound features a unique structure that includes multiple amino groups, which contributes to its reactivity and potential interactions within biological systems.
  • Role in Metabolism: Compounds like this are often involved in metabolic pathways, acting as intermediates or as important substrates for enzymatic reactions.
  • Potential as a Drug Candidate: Due to its structure, it may serve as a scaffold for developing new therapeutics. In drug design, modifications of such compounds can lead to improved efficacy and reduced side effects.
  • Research Interest: Scientists are particularly interested in investigating this compound as it may impact neurotransmission and cellular signaling pathways.
  • Biological Importance: With its amino acid nature, it could play a role in protein synthesis or act as a building block for peptides, making it vital in biological studies.

2-Amino-5-[[amino(dimethylamino)methylene]amino]pentanoic acid serves as a testament to the complexity of chemical compounds and their roles in life sciences. As researchers continue to explore its properties, we gain deeper insights into the underlying principles of biochemistry and molecular biology.

Synonyms
n-dimethylarginine
2-amino-5-(amino-dimethylamino-methylidene)amino-pentanoic acid
850208-77-4
"N,N-DIMETHYLARGININE"
SCHEMBL12028770
DTXSID60860788
CHEBI:181449
YDGMGEXADBMOMJ-UHFFFAOYSA-N
N(G),N(G')-Dimethyl-L-arginine
2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid
2aAminoa5a(N',N'adimethylcarbamimidamido)pentanoic acid
(2S)-2-amino-5-[[amino-[bis(trideuteriomethyl)amino]methylidene]amino]pentanoic acid