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Adenosine monophosphate

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
2-amino-5-[[amino-[[5-[[[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-3,4-dihydroxy-tetrahydrofuran-2-yl]amino]methylene]amino]pentanoic acid
State
State
At room temperature, adenosine monophosphate is a solid.
Melting point (Celsius)
185.00
Melting point (Kelvin)
458.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
2.1401g/cm3
Appearence

Adenosine monophosphate (AMP) typically appears as a white to off-white crystalline powder. It is a nucleotide that consists of a phosphate group, the pentose sugar ribose, and the nucleobase adenine.

Comment on solubility

Solubility of 2-amino-5-[[amino-[[5-[[[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-3,4-dihydroxy-tetrahydrofuran-2-yl]amino]methylene]amino]pentanoic acid

The solubility of 2-amino-5-[[amino-[[5-[[[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-3,4-dihydroxy-tetrahydrofuran-2-yl]amino]methylene]amino]pentanoic acid (C10H14N5O7P) is influenced by several key factors:

  • Functional Groups: The presence of multiple hydroxyl groups (–OH) and amino groups (–NH2) generally enhances water solubility due to hydrogen bonding.
  • Polarity: This compound is polar in nature because of its ionic and hydrogen bonding potential, making it more likely to dissolve in polar solvents like water.
  • pH Dependence: Being an amino acid derivative, its solubility may vary with pH. At physiological pH levels, the compound is more soluble.

In general, amino acids and their derivatives demonstrate good solubility in water, which is beneficial for applications in biochemistry and pharmacology. The solubility characteristics allow for better bioavailability and easier formulation in various pharmaceutical preparations.

However, the detailed solubility profile might require empirical data and experiments to confirm, as solubility can be influenced by various environmental conditions and other solutes present in the solution.

Interesting facts

Interesting Facts about 2-amino-5-[[amino-[[5-[[[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-3,4-dihydroxy-tetrahydrofuran-2-yl]amino]methylene]amino]pentanoic acid

This compound, with a rather complex name, is a fascinating example of a bioactive molecule. Its structure reveals a rich tapestry of functionalities that is characteristic of many important biochemical pathways. Here are some of the most intriguing aspects:

  • Biological Significance: This compound is related to metabolic processes and plays a role in nucleotide synthesis. Its complex framework indicates a potential role in cellular regulation and signal transduction.
  • Structure-Activity Relationship: The numerous functional groups such as amino, methoxy, and phosphate contribute to its potential interactions with biological molecules, which can be essential in medicinal chemistry.
  • Tetrahydrofuran Moiety: The presence of tetrahydrofuran rings indicates the compound may possess interesting stereochemistry and conformational flexibility, which can influence its biological activities.
  • Research Potential: Surrounded by a network of amino acids and phosphoryl groups, this compound may be of interest in drug design, particularly for developing treatments related to genetic disorders or cancer.
  • Comparative Analysis: When studying similar bioactive molecules, the structure of this compound allows chemists to draw analogies with nucleosides and nucleotides, providing insight into synthetic pathways and therapeutic applications.

In summary, the intricacy of this compound not only reflects its potential therapeutic applications but also highlights the beauty of molecular architecture in chemistry. As researchers delve deeper into its synthesis and mechanisms of action, we can expect to uncover more about how such compounds influence biological systems.

Synonyms
2-amino-5-[[amino-[[5-[[[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]amino]methylidene]amino]pentanoic acid
N(w)-(ADP-D-ribosyl)-arginine
N2-(ADP-D-ribosyl)-L-arginine
N(w)-(ADP-D-ribosyl)-L-arginine
N(omega)-(ADP-D-ribosyl)-arginine
N(w)-(ADP-delta-ribosyl)-arginine
N2-(ADP-delta-ribosyl)-L-arginine
N(w)-(ADP-delta-ribosyl)-L-arginine
N(omega)-(ADP-delta-ribosyl)-arginine
N(omega)-(ADP-delta-ribosyl)-L-arginine