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Glutathione

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Identification
Molecular formula
C10H17N3O6S
CAS number
70-18-8
IUPAC name
2-amino-5-[[2-(carboxymethylamino)-1-(disulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid
State
State

Glutathione is a solid at room temperature and is an important antioxidant in plants, animals, fungi, and some bacteria and archaea, preventing damage to cellular components caused by reactive oxygen species such as free radicals and peroxides.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
306.00
Boiling point (Kelvin)
579.15
General information
Molecular weight
307.32g/mol
Molar mass
307.3230g/mol
Density
1.3400g/cm3
Appearence

Glutathione is typically a white crystalline powder. It is odorless and exists as a solid at room temperature. The appearance may vary slightly based on purity and form.

Comment on solubility

Solubility of 2-amino-5-[[2-(carboxymethylamino)-1-(disulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

The solubility of 2-amino-5-[[2-(carboxymethylamino)-1-(disulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid, with the formula C10H17N3O6S, can be characterized by several important factors:

  • Polarity: This compound contains multiple functional groups, including amine, carboxylic acid, and sulfonyl groups, which contribute to its high polarity. As a result, it is expected to have good solubility in polar solvents, particularly water.
  • pH Dependency: Due to the presence of acidic and basic functional groups, the solubility may vary with pH. At lower pH levels, the carboxylic acid group is likely to remain protonated, potentially enhancing solubility.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules further facilitates solubility. The presence of amino and carboxyl groups can interact favorably with water.
  • Temperature: Like many compounds, an increase in temperature could lead to greater solubility as thermal energy can disrupt intermolecular interactions.

In conclusion, we anticipate that 2-amino-5-[[2-(carboxymethylamino)-1-(disulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid will exhibit good solubility in water and other polar solvents due to its complex structure and functional groups. The variations in temperature and pH also provide avenues for understanding its solubility in different environments.

Interesting facts

Interesting Facts about 2-amino-5-[[2-(carboxymethylamino)-1-(disulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

2-amino-5-[[2-(carboxymethylamino)-1-(disulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid is a fascinating and complex compound with a variety of intriguing properties and potential applications.

Biological Significance

This compound is known for its role in biological systems, particularly in the realm of amino acids and peptide synthesis. Here are some noteworthy points:

  • Structural Role: It contains functional groups such as carboxylic acids and amines, which are critical in forming the backbone of peptides.
  • Disulfide Bonds: The presence of disulfanylmethyl groups highlights its potential for forming disulfide bridges in proteins, crucial for protein folding and stability.
  • Metabolic Pathways: It may participate in metabolic pathways relevant to amino acid metabolism, thus influencing various biological processes.

Research and Applications

This compound holds particular interest in scientific research and therapeutic applications:

  • Drug Development: Its unique structure suggests potential for use in drug design, especially in targeting metabolic diseases or cancer.
  • Bioconjugation: The amino and carboxylic functionalities make it an excellent candidate for bioconjugation strategies in pharmaceutical chemistry.
  • Antioxidant Properties: Its disulfide components may confer antioxidant properties, making it useful in studies related to oxidative stress.

Chemical Characteristics

The complex nature of this compound allows for various chemical transformations, enhancing its versatility. Notably, it can participate in:

  • Acid-Base Reactions: The amino and carboxyl groups engage in proton transfer reactions, fundamental in biochemical pathways.
  • Redox Reactions: The disulfide bonds can undergo redox reactions, which are pivotal in cellular signaling.

In conclusion, 2-amino-5-[[2-(carboxymethylamino)-1-(disulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid is not just a compound of interest due to its structure, but also for its vast potential in various scientific fields. As we explore the frontiers of chemistry and biology, this molecule may reveal even more secrets about life and health.

Synonyms
SCHEMBL15368874