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Glutathione

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Identification
Molecular formula
C10H17N3O6S
CAS number
70-18-8
IUPAC name
2-amino-5-[[2-[[2-[4-[3-[[2-[[2-[(4-amino-4-carboxy-butanoyl)amino]-3-sulfanyl-propanoyl]amino]acetyl]amino]propylamino]butylamino]-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid
State
State

At room temperature, Glutathione is usually in a solid crystalline state.

Melting point (Celsius)
195.50
Melting point (Kelvin)
468.50
Boiling point (Celsius)
258.00
Boiling point (Kelvin)
531.00
General information
Molecular weight
307.32g/mol
Molar mass
307.3230g/mol
Density
1.4000g/cm3
Appearence

Glutathione is a white crystalline powder. It is a tri-peptide composed of the amino acids glutamine, cysteine, and glycine, and it is highly soluble in water, giving a clear solution. It's often used in research as a standard reagent and can appear in various forms including reduced and oxidized states.

Comment on solubility

Solubility of 2-amino-5-[[2-[[2-[4-[3-[[2-[[2-[(4-amino-4-carboxy-butanoyl)amino]-3-sulfanyl-propanoyl]amino]acetyl]amino]propylamino]butylamino]-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid

The solubility of complex organic compounds, such as 2-amino-5-[[2-[[2-[4-[3-[[2-[[2-[(4-amino-4-carboxy-butanoyl)amino]-3-sulfanyl-propanoyl]amino]acetyl]amino]propylamino]butylamino]-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid (C10H17N3O6S) can vary significantly based on several factors:

  • Molecular Structure: The presence of functional groups such as amino, carboxyl, and sulfonyl can enhance solubility in polar solvents.
  • Solvent Polarity: This compound is likely to be soluble in water due to its hydrophilic groups, which promote hydrogen bonding.
  • pH Levels: The solubility may be affected by the pH of the solution, particularly because of the carboxylic acid group.
  • Hydrogen Bonding: The ability to form hydrogen bonds with the solvent will significantly increase its solubility.
  • Temperature: Increased temperature typically enhances the solubility of solids in liquids.

In summary, while this compound possesses a complex structure that suggests it has some solubility in aqueous solutions, the specific conditions such as solvent type, temperature, and pH will ultimately dictate the extent of its solubility. It is important to carry out experimental measurements to precisely determine its solubility characteristics.

Interesting facts

Interesting Facts about 2-amino-5-[[2-[[2-[4-[3-[[2-[[2-[(4-amino-4-carboxy-butanoyl)amino]-3-sulfanyl-propanoyl]amino]acetyl]amino]propylamino]butylamino]-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid

This compound represents a fascinating intersection of amino acids and peptide synthesis, showcasing the immense complexity achievable in organic chemistry. Below are several intriguing aspects worth noting:

  • Bioactive Potential: With multiple amino groups and functionalized sites, this compound could exhibit important biological properties, possibly serving as a candidate for drug development or therapeutic applications.
  • Peptide Design: The structural complexity reflects its potential use in the design of novel peptides, which are crucial for numerous biological processes.
  • Research Applications: Its assembly could be utilized for the investigation of protein interactions, ligand binding studies, or as a model compound in enzymatic reactions.
  • Scientific Discovery: The intricate nature of this molecular structure illustrates the advancements in synthetic chemistry, where the ability to create such compounds could lead to new discoveries and applications in biochemical research.

As a chemistry student, the exploration of such complex molecules opens a door to a deeper understanding of biochemical pathways and the development of new methodologies in synthesis. There’s a popular quote in the field that says, "Chemistry is the music of the universe;" and through such compounds, one can certainly appreciate the harmony and intricacy present in the molecular world.

This compound stands as a testament to the creativity and analytical skills required in the field of chemistry, bridging the gap between theoretical knowledge and practical application.