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Glutathione

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Identification
Molecular formula
C10H17N3O6S
CAS number
70-18-8
IUPAC name
2-amino-5-[[2-[[2-[3-(4-aminobutylamino)propylamino]-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid
State
State

Glutathione is typically found in a solid state at room temperature.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
337.84
Boiling point (Kelvin)
610.99
General information
Molecular weight
307.32g/mol
Molar mass
307.3230g/mol
Density
1.4400g/cm3
Appearence

Glutathione appears as a white crystalline powder. It can also be a whitish or pale-yellow solid when impure.

Comment on solubility

Solubility of 2-amino-5-[[2-[[2-[3-(4-aminobutylamino)propylamino]-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid

The solubility of the compound with the formula C10H17N3O6S is an intriguing consideration due to its complex structure. Here are some key points to understand its solubility characteristics:

  • Water Solubility: The presence of multiple amino and carboxyl groups suggests that this compound is likely to be soluble in water. These functional groups can form hydrogen bonds with water molecules, enhancing its solubility.
  • Effect of pH: The solubility may vary significantly with changes in pH. At acidic pH levels, protonation of amino groups can increase solubility, while at alkaline conditions, deprotonation of carboxylic acid groups can also enhance solubility.
  • Influence of Temperature: Generally, increasing the temperature may improve the solubility of many compounds. However, the specific response can vary based on the interactions present.
  • Solvent Polarity: Although water is a primary solvent, the solubility in organic solvents may be limited. Testing with different polar aprotic solvents (like DMSO or DMF) could reveal varying solubility profiles.

Overall, the complex interplay of functional groups leads to a high probability of solubility in aqueous environments, which is critical for its potential biological applications. As with many organic compounds, understanding the specific solubility behavior can guide its usage in various formulations and chemical processes.

Interesting facts

Interesting Facts about 2-amino-5-[[2-[[2-[3-(4-aminobutylamino)propylamino]-2-oxo-ethyl]amino]-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid

This compound is an intriguing example of a multifunctional molecule that exhibits various biological and chemical properties. Here are some interesting facts:

  • Biological Activity: Compounds like this one often have significant roles in biological systems, particularly as biological precursors or in pharmaceuticals. They may interact with specific pathways, serving therapeutic purposes.
  • Structure Complexity: The intricate structure of this compound, featuring multiple functional groups including amines, carboxylic acids, and a sulfanylmethyl group highlights the vast potential in organic synthesis and chemical reactivity.
  • Carbon Skeleton: The pentanoic acid backbone allows for versatile chemistry, making it an interesting target for synthetic chemists interested in modifying natural products or developing new compounds with enhanced properties.
  • Potential Uses: Researchers might explore its use in drug delivery systems, given its ability to form complex interactions with biological targets, or in developing novel antitumor agents.
  • Chemical Interactions: The presence of multiple amino and oxo groups suggests that this compound may participate in various hydrogen bonding and electrostatic interactions, which is crucial in biological activity and material science.

In summary, this compound is a noteworthy candidate for research due to its potential applications in medicine and its rich chemistry, making it a subject of ongoing interest within chemical and biological sciences.

Synonyms
Glutathionylspermidine I
2-amino-5-[[1-[[2-[3-(4-aminobutylamino)propylamino]-2-oxoethyl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
2-Amino-4-((1-((((3-((4-aminobutyl)amino)propyl)-C-hydroxycarbonimidoyl)methyl)-C-hydroxycarbonimidoyl)-2-sulfanylethyl)-C-hydroxycarbonimidoyl)butanoate
2-Amino-4-((1-((((3-((4-aminobutyl)amino)propyl)-C-hydroxycarbonimidoyl)methyl)-C-hydroxycarbonimidoyl)-2-sulphanylethyl)-C-hydroxycarbonimidoyl)butanoate
2-Amino-4-((1-((((3-((4-aminobutyl)amino)propyl)-C-hydroxycarbonimidoyl)methyl)-C-hydroxycarbonimidoyl)-2-sulphanylethyl)-C-hydroxycarbonimidoyl)butanoic acid
2-Amino-4-[(1-{[({3-[(4-aminobutyl)amino]propyl}-C-hydroxycarbonimidoyl)methyl]-C-hydroxycarbonimidoyl}-2-sulfanylethyl)-C-hydroxycarbonimidoyl]butanoate
2-Amino-4-[(1-{[({3-[(4-aminobutyl)amino]propyl}-C-hydroxycarbonimidoyl)methyl]-C-hydroxycarbonimidoyl}-2-sulphanylethyl)-C-hydroxycarbonimidoyl]butanoate
2-Amino-4-[(1-{[({3-[(4-aminobutyl)amino]propyl}-C-hydroxycarbonimidoyl)methyl]-C-hydroxycarbonimidoyl}-2-sulphanylethyl)-C-hydroxycarbonimidoyl]butanoic acid
2-amino-5-((1-((2-(3-(4-aminobutylamino)propylamino)-2-oxoethyl)amino)-1-oxo-3-sulfanylpropan-2-yl)amino)-5-oxopentanoic acid
CHEBI:205980
2-amino-5-[[1-[[2-[3-(4-aminobutylamino)propylamino]-2-oxoethyl]amino]-1-oxo-3-sulanylpropan-2-yl]amino]-5-oxopentanoic acid