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Bambuterol

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Identification
Molecular formula
C13H18N2O2
CAS number
81732-65-2
IUPAC name
2-amino-5-[1-hydroxy-2-(isopropylamino)ethyl]benzonitrile
State
State

Bambuterol is generally in a solid state at room temperature.

Melting point (Celsius)
58.00
Melting point (Kelvin)
331.15
Boiling point (Celsius)
368.20
Boiling point (Kelvin)
641.35
General information
Molecular weight
265.34g/mol
Molar mass
265.3400g/mol
Density
1.1200g/cm3
Appearence

Bambuterol typically appears as a white to off-white crystalline powder. It is often odorless or has a very faint characteristic odor.

Comment on solubility

Solubility of 2-amino-5-[1-hydroxy-2-(isopropylamino)ethyl]benzonitrile

The compound 2-amino-5-[1-hydroxy-2-(isopropylamino)ethyl]benzonitrile, with the chemical formula C13H18N2O2, exhibits intriguing solubility characteristics that can be influenced by various factors:

  • Polarity: Due to the presence of polar functional groups (such as amino and hydroxyl), this compound is likely to have greater solubility in polar solvents like water.
  • Hydrogen bonding: The hydroxyl group can form hydrogen bonds with water molecules, enhancing solubility and facilitating dissociation in aqueous conditions.
  • Hydrophobic interactions: The isopropyl group introduces hydrophobic characteristics that may affect solubility, potentially leading to decreased solubility in non-polar solvents.
  • Temperature dependence: Like many organic compounds, the solubility may increase with temperature, showcasing a typical temperature-sensitivity behavior.

In conclusion, the solubility of this compound can be classified as moderate to high in polar solvents while being low in non-polar solvents. Understanding these solubility traits is crucial for applications in drug formulation and chemical synthesis. As the saying goes, "like dissolves like," so considering the interplay of structural features is essential in predicting solubility behavior.

Interesting facts

Interesting Facts about 2-amino-5-[1-hydroxy-2-(isopropylamino)ethyl]benzonitrile

2-amino-5-[1-hydroxy-2-(isopropylamino)ethyl]benzonitrile is a fascinating compound that belongs to the family of benzonitriles, known for their diverse biological activities. This compound exhibits several noteworthy properties:

  • Pharmaceutical Relevance: Compounds like this one often serve as precursors or intermediates in the synthesis of various pharmaceuticals, illustrating the intricate relationship between organic chemistry and medicinal chemistry.
  • Structural Complexity: The structure of this compound features a benzene ring substituted with both an amino group and a hydroxyl group, showcasing the intricate ways in which functional groups can modify chemical behavior.
  • Biological Activity: Many similar compounds are investigated for their potential pharmacological properties, including their effectiveness as anti-arrhythmic agents or their role in treating conditions such as hypertension.
  • Synthesis Challenges: The synthesis of compounds with such complex structures can be challenging, often requiring advanced synthetic techniques such as asymmetric synthesis or multi-step reactions to achieve the desired configuration.

As noted by chemists, “Understanding the interplay between a compound's structure and its biological activity is essential for drug development.” This emphasizes the importance of studying compounds like 2-amino-5-[1-hydroxy-2-(isopropylamino)ethyl]benzonitrile in the quest for new therapeutic agents.

In summary, the study of this compound not only enhances our knowledge of organic chemistry but also contributes to the broader field of medicinal chemistry, opening doors to the development of new medications.

Synonyms
cimaterol
54239-37-1
Cimater
cimatrol
Cimaterolum
AB-A 663
Cimaterolum [Latin]
AC 263,780
Cimaterol [USAN:INN]
ZPY8VRF0GB
ABA-663
2-amino-5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzonitrile
DTXSID2045652
AC-263780
AB-A 66
AB-A-66
CIMATEROL [INN]
CL-263,780
CIMATEROL [MI]
CIMATEROL [USAN]
Benzonitrile, 2-amino-5-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-, (+-)-
DTXCID0025652
(+-)-5-(1-Hydroxy-2-(isopropylamino)ethyl)anthranilonitrile
Cimaterol D7
Cimaterolum (Latin)
NCGC00024589-02
Cimaterol 100 microg/mL in Acetonitrile
2-amino-5-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzonitrile
CL 263780;CL-263780;CL263780
2-Amino-5-[1-hydroxy-2-(isopropylamino)ethyl]benzonitrile
(+/-)-5-(1-HYDROXY-2-(ISOPROPYLAMINO)ETHYL)ANTHRANILONITRILE
BENZONITRILE, 2-AMINO-5-(1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)-, (+/-)-
CAS-54239-37-1
UNII-ZPY8VRF0GB
2-amino-5-(1-hydroxy-2-(propan-2-ylamino)ethyl)benzonitrile
CL 263,780
2-Amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]benzonitrile; CL 263780; Cimaterol
MFCD00209815
5-(1-hydroxy-2-(isopropylamino)ethyl)anthranilonitrile
Cimaterol (USAN/INN)
Benzonitrile, 2-amino-5-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-
BSPBio_001582
KBioGR_000302
KBioSS_000302
SCHEMBL250088
CHEMBL1374751
BCBcMAP01_000252
CHEBI:91807
GTPL12578
KBio2_000302
KBio2_002870
KBio2_005438
KBio3_000603
KBio3_000604
MSK1309
BUXRLJCGHZZYNE-UHFFFAOYSA-N
Bio1_000410
Bio1_000899
Bio1_001388
Bio2_000302
Bio2_000782
HMS1361P04
HMS1791P04
HMS1989P04
HMS2089K03
HMS3266O17
HMS3402P04
HMS3414G13
HMS3678G13
AB-A-663
Tox21_110908
BDBM50432700
AKOS022653417
Tox21_110908_1
1ST1309
FC20437
IDI1_034052
NCGC00024589-03
NCGC00024589-04
NCGC00024589-05
NCGC00024589-06
AS-55897
A8042
NS00000687
Cimaterol, VETRANAL(TM), analytical standard
A11658
D03502
EN300-384082
AB01275431-01
SR-01000597648
Q5120112
SR-01000597648-1
BRD-A65440446-001-02-5
BRD-A65440446-001-03-3
BRD-A65440446-001-04-1
Z1509141766
2-Amino-5-[1-hydroxy-2-(isopropylamino)ethyl]benzonitrile #
(.+/-.)-5-[1-Hydroxy-2-(isopropylamino)ethyl]anthranilonitrile
2-Amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]benzonitrile;Cimaterol
Benzonitrile, 2-amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, (.+/-.)-