Azidocillin | Solubility of Things

Identification

Molecular formula

C₁₉H₁₉N₅O₆S

CAS number

51092-55-2

IUPAC name

2-amino-5-[[1-[[2-(4-azidophenyl)-2-oxo-ethyl]sulfanylmethyl]-2-(carboxymethylamino)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

State

At room temperature, Azidocillin is typically in a solid state, appearing as a crystalline powder. It is stable under normal temperatures and pressures.

Melting point (Celsius)

208.00

Melting point (Kelvin)

481.15

Boiling point (Celsius)

120.00

Boiling point (Kelvin)

393.15

General information

Molecular weight

433.46g/mol

Molar mass

433.4550g/mol

Density

1.3600g/cm³

Appearence

Azidocillin typically appears as a white crystalline powder. It is often odorless or has a slight chemical smell. The crystalline nature of the compound makes it suitable for various pharmaceutical applications.

Comment on solubility

Solubility of 2-amino-5-[[1-[[2-(4-azidophenyl)-2-oxo-ethyl]sulfanylmethyl]-2-(carboxymethylamino)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

The solubility of the compound 2-amino-5-[[1-[[2-(4-azidophenyl)-2-oxo-ethyl]sulfanylmethyl]-2-(carboxymethylamino)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid (C₁₉H₁₉N₅O₆S) is influenced by its complex structure. Here are some key points regarding its solubility:

Polarity: The presence of multiple functional groups, including amino (-NH₂), carboxylic acid (-COOH), and sulfonyl groups, suggests that the compound could exhibit significant polar characteristics, which may enhance solubility in polar solvents such as water.
Hydrogen Bonding: The ability of the compound to engage in hydrogen bonding due to its amino and carboxylic acid functional groups potentially increases its solubility in aqueous solutions.
Aromatic Group: The presence of the 4-azidophenyl moiety can affect solubility due to its hydrophobic nature, which might lead to limited solubility in non-polar solvents.
Overall Behavior: While the compound may dissolve well in aqueous media due to its polar functional groups, its solubility may vary significantly based on factors such as pH, temperature, and the presence of other solutes.

In summary, the solubility of this compound is likely to be influenced by both its polar and non-polar attributes, making it suitable for solubility studies under various chemical conditions.

Interesting facts

Interesting Facts about 2-amino-5-[[1-[[2-(4-azidophenyl)-2-oxo-ethyl]sulfanylmethyl]-2-(carboxymethylamino)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

2-amino-5-[[1-[[2-(4-azidophenyl)-2-oxo-ethyl]sulfanylmethyl]-2-(carboxymethylamino)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid, often shortened to its complex abbreviation, is a compound of considerable interest within the realm of medicinal chemistry and biochemistry. Here are some notable aspects:

Dual Functionality: This compound exhibits both aminic and azide functionalities, making it a versatile precursor in bioorthogonal chemistry. The azide group can undergo click reactions, which are essential for tagging biomolecules in cellular studies.
Potential in Drug Development: Thanks to its ability to interact with biological systems, researchers are exploring its role as a lead compound in the design of novel therapeutics aimed at targets associated with disease pathways.
Peptide Analog: The incorporation of amino acids in its structure suggests potential applications as a peptide analog, which can enhance the selectivity and efficacy of certain biological interactions.
Environmental Stability: The presence of multiple functional groups in the molecule may impart enhanced stability under various environmental conditions, making it suitable for formulative processes in pharmaceutical science.

In summary, the intriguing structure and reactivity profile of 2-amino-5-[[1-[[2-(4-azidophenyl)-2-oxo-ethyl]sulfanylmethyl]-2-(carboxymethylamino)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid set the stage for exciting research opportunities. Its applications could pave the way for advancements in both synthetic methodologies and therapeutic innovations.