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Thiamine pyrophosphate

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Identification
Molecular formula
C12H17N4O7P
CAS number
154-87-0
IUPAC name
[2-amino-4-oxo-6,7-bis(sulfanyl)-1,5,5a,8,9a,10-hexahydropyrano[3,2-g]pteridin-8-yl]methyl dihydrogen phosphate
State
State

At room temperature, thiamine pyrophosphate is in a solid state. It is stable when kept in dry conditions, but it is hygroscopic and should be stored in airtight containers to prevent absorption of moisture from the air.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
422.32g/mol
Molar mass
422.3240g/mol
Density
1.3650g/cm3
Appearence

Thiamine pyrophosphate is an odorless, crystalline white powder. It is typically observed as a dry and fine substance, appearing either colorless or with a subtle yellow tint.

Comment on solubility

Solubility of [2-amino-4-oxo-6,7-bis(sulfanyl)-1,5,5a,8,9a,10-hexahydropyrano[3,2-g]pteridin-8-yl]methyl dihydrogen phosphate

The solubility of the compound C12H17N4O7P, also known as [2-amino-4-oxo-6,7-bis(sulfanyl)-1,5,5a,8,9a,10-hexahydropyrano[3,2-g]pteridin-8-yl]methyl dihydrogen phosphate, can be influenced by various factors:

  • Polarity: The presence of functional groups such as phosphate groups and amino groups typically increases solubility in polar solvents, most notably water.
  • Hydrogen Bonding: This compound can engage in hydrogen bonding due to its amino and phosphate groups, further enhancing its solubility in polar environments.
  • Temperature: Generally, solubility can increase with temperature for many compounds, though exceptions exist depending on interactions within the compound and solvent.

It is important to note that while some compounds show good solubility in aqueous solutions, others may require organic solvents or specific pH conditions to enhance dissolvability. In the case of this complex molecule, the combination of both polar and non-polar characteristics may lead to varied solubility profiles:

  1. **Highly soluble in polar solvents such as water at certain pH**
  2. **Moderate solubility in non-polar organic solvents**

In conclusion, understanding the solubility characteristics of this compound is essential for applications in biological systems and pharmaceutical formulations, where solubility influences bioavailability and therapeutic efficacy.

Interesting facts

Interesting Facts about [2-amino-4-oxo-6,7-bis(sulfanyl)-1,5,5a,8,9a,10-hexahydropyrano[3,2-g]pteridin-8-yl]methyl dihydrogen phosphate

This fascinating compound belongs to a class of molecules known for their intricate structures and diverse biological activities. Here are some intriguing aspects about it:

  • Biological Significance: Compounds with similar structures are often investigated for their potential medicinal properties, particularly in pharmacology. They can serve as leads for drug development, targeting various diseases.
  • Structural Complexity: The presence of both sulfanyl and di-hydrogen phosphate groups illustrates the compound's intricate nature, making it an interesting subject for chemists interested in how structure influences function.
  • Potential Applications: Researchers are exploring the use of related compounds in treating conditions such as cancer and inflammatory diseases, given their unique mechanisms of action.
  • Versatile Intermediates: This compound can serve as an intermediate in the synthesis of more complex organic molecules, showcasing the interconnectedness of chemical reactions in synthetic organic chemistry.
  • Research Potential: Its unique arrangement and functional groups present opportunities for further research to uncover novel properties that might lead to significant breakthroughs in scientific knowledge.
  • Adapting Chemistry for Innovation: Developing new compounds with altered structures can lead to varying biological activities. This particular compound exemplifies how slight modifications can yield profound results.

Overall, the exploration of such complex compounds continues to be a vital aspect of modern chemistry, driving innovation and uncovering potential therapeutic avenues. Its study not only enriches our understanding of chemical principles but also opens doors to future discoveries.