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Threonine

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Identification
Molecular formula
C4H9NO3
CAS number
80-68-2
IUPAC name
2-amino-4-hydroxy-pentanedioic acid
State
State

Threonine is generally found in the solid state at room temperature.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
149.09g/mol
Molar mass
149.0870g/mol
Density
1.6600g/cm3
Appearence

Threonine is a white crystalline solid. It is typically found as a powder or small crystals and is often described as having a somewhat sweet taste. The purity and form can slightly alter its exact appearance, but it is predominantly recognized as a white solid.

Comment on solubility

Solubility of 2-amino-4-hydroxy-pentanedioic acid (C4H9NO3)

2-amino-4-hydroxy-pentanedioic acid, commonly known as aspartic acid, presents interesting solubility characteristics due to its molecular structure and the presence of various functional groups. The solubility of this compound can be influenced by several factors:

  • Polarity: The amino (-NH2) and hydroxyl (-OH) groups increase the polarity of the molecule, enabling it to interact favorably with polar solvents, particularly water.
  • Amino Acids Behavior: As a dicarboxylic acid, 2-amino-4-hydroxy-pentanedioic acid can exist in both acidic and basic forms, affecting its solubility in different pH environments.
  • Temperature Effects: Like many organic compounds, the solubility of aspartic acid generally increases with temperature, allowing for greater dissolution in warm solutions.

In summary, 2-amino-4-hydroxy-pentanedioic acid is highly soluble in water, which makes it quite useful in various biochemical applications. Its ability to dissolve effectively in polar solvents can be attributed to the presence of both functional groups that enhance interactions with the solvent, thus confirming its status as an amino acid often involved in biological processes.

Interesting facts

Introduction to 2-amino-4-hydroxy-pentanedioic acid

2-amino-4-hydroxy-pentanedioic acid, commonly known as Asparagine, is a fascinating amino acid that plays a crucial role in various biological processes. It is one of the 20 standard amino acids used by cells to synthesize proteins. Below are some interesting facts that highlight the significance of this compound:

Biological Importance

  • Protein Synthesis: Asparagine is essential for the formation of proteins, serving as a building block in polypeptide chains.
  • Metabolic Role: This amino acid is involved in nitrogen metabolism and balances the nitrogen levels in organisms.
  • Neurotransmitter Function: Asparagine plays a role in the synthesis of neurotransmitters, contributing to neurological health.

Health Benefits

  • Support for Athletic Performance: It is believed to aid in recovery and decrease fatigue during intense exercise.
  • Role in Cellular Growth: Asparagine is vital for cellular division and growth, making it crucial during periods of rapid growth, such as childhood and pregnancy.
  • No Side Effects: Occasional supplementation is generally regarded as safe, contributing to its popularity in the fitness community.

Chemical Characteristics

In addition to its biological roles, the structural properties of 2-amino-4-hydroxy-pentanedioic acid contribute to its functionality:

  • Hydrophobic Nature: The hydroxy group enhances its solubility in water, promoting its bioavailability in physiological environments.
  • Charge Distribution: The amino group adds a positive charge at physiological pH, affecting the interaction of this amino acid with other biomolecules.

Interesting Anecdotes

While researching 2-amino-4-hydroxy-pentanedioic acid, you'll find some astonishing facts:

  • It was first isolated in 1806 from asparagus, which is why the compound bears the name "asparagine."
  • Asparagine can be synthesized by the body, though dietary sources are often encouraged, especially for athletes.
  • It's considered a non-essential amino acid, meaning the body can produce it, but under certain conditions, like illness, additional intake may be beneficial.

In conclusion, 2-amino-4-hydroxy-pentanedioic acid is not just a simple amino acid; it is a compound with profound implications in biology, health, and metabolism. Its versatility and importance make it a topic worthy of deep exploration within the field of biochemistry.

Synonyms
2-amino-4-hydroxypentanedioic acid
Hydroxyglutamic acid
H-(2S,4S)-Gamma-Hydroxy-Glu-OH
3157-41-3
(4R)-4-Hydroxy-L-glutamic acid
H-(2S,4R)-Gamma-Hydroxy-Glu-OH
UNII-MB5HCK64QF
MB5HCK64QF
4-hydroxy-dl-glutamic acid
(2S,4R)-2-ammonio-4-hydroxypentanedioate
SCHEMBL305904
DTXSID20863114
DTXSID80274287
CHEBI:197035
EINECS 208-572-5
NSC206306
NSC206309
(2S,4R)-g-Hydroxy-L-glutamic acid
NSC-206306
NSC-206309
erythro-4-Hydroxy-L-glutamic acid(1-)
PD197624
NS00121828
(2S,4R)-2-ammonio-4-Hydroxypentanedioic acid
56614-13-2