Skip to main content

Threonine

ADVERTISEMENT
Identification
Molecular formula
C4H9NO3
CAS number
72-19-5
IUPAC name
2-amino-4-hydroxy-butanoic acid
State
State

Threonine is a solid at room temperature, generally presented as a powder for supplement purposes due to its use as an essential amino acid.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
119.12g/mol
Molar mass
119.1190g/mol
Density
1.4480g/cm3
Appearence

Threonine appears as white or colorless crystals. It is typically supplied as a crystalline powder that is not completely soluble in water.

Comment on solubility

Solubility of 2-amino-4-hydroxy-butanoic acid (C4H9NO3)

2-amino-4-hydroxy-butanoic acid, commonly known as serine, exhibits interesting solubility properties that are essential for its role in biological systems. Here are some key points about its solubility:

  • Solvent Interaction: This compound is highly soluble in water due to its ability to form hydrogen bonds with water molecules. The presence of both amino (-NH2) and hydroxyl (-OH) groups enhances its hydrophilicity.
  • Temperature Effect: Generally, the solubility of amino acids like serine tends to increase with temperature, making it more soluble in warmer water.
  • pH Dependence: The solubility can vary with pH, as it can exist in different ionic forms (zwitterionic states) depending on the pH of the solution.
  • Comparison to Other Amino Acids: Compared to hydrophobic amino acids, serine’s polar nature allows it to dissolve well in aqueous solutions.

In summary, the solubility of 2-amino-4-hydroxy-butanoic acid is significantly influenced by its chemical structure, temperature, and the pH of the surrounding environment, making it readily available for various metabolic processes in the body. Its strong solubility profile aligns with its essential functions in protein synthesis and neurotransmitter activity.

Interesting facts

Interesting Facts About 2-Amino-4-Hydroxy-Butanoic Acid

2-Amino-4-hydroxy-butanoic acid, commonly known as l-theanine, is a fascinating compound mainly found in tea leaves, particularly in green tea. As a significant amino acid, it plays a crucial role in various biological processes and has gained popularity in health and wellness circles.

Key Attributes

  • Structure: This compound features both amino and hydroxyl functional groups, which contribute to its unique properties and effects on the human body.
  • Brain Effects: Research suggests that l-theanine can promote relaxation without drowsiness, making it an excellent complement to caffeine, often enhancing focus and cognitive performance.
  • Neurotransmitters: It is believed to influence levels of neurotransmitters such as GABA, dopamine, and serotonin, which are essential for mood regulation and mental health.
  • Antioxidant Properties: L-theanine possesses antioxidant properties, allowing it to combat oxidative stress and protect cells from damage.

Applications in Everyday Life

Beyond its natural occurrence in tea, 2-amino-4-hydroxy-butanoic acid is widely used as a dietary supplement. Some noteworthy applications include:

  • Stress Relief: Many individuals take l-theanine supplements to help alleviate stress and promote a sense of calm.
  • Enhanced Sleep Quality: It is often included in sleep aids due to its potential to improve sleep quality without causing sedation.
  • Cognitive Function Booster: Students and professionals alike may utilize it as a cognitive enhancer, especially in conjunction with caffeine during study sessions or demanding tasks.

In summary, 2-amino-4-hydroxy-butanoic acid is not just an amino acid; it is a multi-faceted compound with wide-reaching benefits and applications. Its ability to foster relaxation, enhance cognitive function, and provide antioxidant support makes it an exciting subject of study for both scientists and wellness enthusiasts alike.

Synonyms
DL-Homoserine
1927-25-9
homoserine
2-amino-4-hydroxybutanoic acid
H-DL-HoSer-OH
D,L-Homoserine
498-19-1
2-amino-4-hydroxy-butanoic acid
MFCD00002618
Homoserine, (+/-)-
JN0F9A0SSO
Butyric acid, 2-amino-4-hydroxy-, DL-
HOMOSERINE, DL
DL-2-Amino-4-hydroxybutyric Acid
EINECS 217-661-8
UNII-JN0F9A0SSO
NSC-37755
CHEBI:30653
NSC 37755
NSC-206251
Isothreonine
Homoserine L-isomer
DL-HOMOSERINE DL-.ALPHA.-AMINO-.GAMMA.-HYDROXYBUTYRIC ACID
L Isomer OF homoserine
HOMOSERINE [MI]
HOMOSERINE, L-
(+/-)-Homoserine
DTXSID5075159
homoserin
L-2-Amino-4-hydroxybutyric acid
2-amino-4-hydroxybutanoate
Homoserine #
S-2-AMINO-4-HYDROXYBUTYRIC ACID
(R)-(+)-2-Amino-4-hydroxybutyric acid
DL-Homoserine, 99%
SCHEMBL29648
DTXCID1036046
DTXSID80862365
ALBB-035712
NSC37755
FD1124
NSC206251
NSC206298
(RS)-2-amino-4-hydroxybutanoic acid
AKOS008105073
AC-5670
CS-W013586
DS-1788
HY-W012870
PB48171
BP-30137
SY005811
SY005812
SY014844
DB-031326
A0319
NS00015554
EN300-53027
Q27113920
F2127-0018
Z234896487
A6F72B1B-294B-4295-BF49-79F879F4FF2B
DL-HOMOSERINE DL-ALPHA-AMINO-GAMMA-HYDROXYBUTYRIC ACID
211-590-6