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Valine

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Identification
Molecular formula
C5H11NO2
CAS number
72-18-4
IUPAC name
2-amino-3-methyl-pentanoic acid
State
State

Valine is in a solid state at room temperature. It remains stable under normal conditions and is not soluble in water, making it suitable for various applications in solid or powdered forms.

Melting point (Celsius)
315.00
Melting point (Kelvin)
588.15
Boiling point (Celsius)
241.20
Boiling point (Kelvin)
514.35
General information
Molecular weight
117.15g/mol
Molar mass
117.1480g/mol
Density
1.2300g/cm3
Appearence

Valine is a white crystalline substance. It is typically available as a powder with no distinct odor, often used in dietary supplements and as a part of protein formulations for various health applications.

Comment on solubility

Solubility of 2-amino-3-methyl-pentanoic acid (C5H11NO2)

2-amino-3-methyl-pentanoic acid, commonly known as a branched-chain amino acid (BCAA), displays notable solubility characteristics due to its molecular structure. Below are key points about its solubility:

  • Water Solubility: This compound exhibits a relatively high solubility in water, which is attributed to its amino (–NH2) and carboxylic acid (–COOH) functional groups. These polar groups facilitate hydrogen bonding with water molecules, enhancing solubility.
  • Solvent Interaction: In addition to water, 2-amino-3-methyl-pentanoic acid is likely to show solubility in other polar organic solvents. This is particularly true for solvents capable of engaging in hydrogen bonding, such as alcohols.
  • Temperature Effect: As is often observed with amino acids, increased temperature can lead to improved solubility. This can be crucial in applications where higher concentrations are required.
  • Buffer Solutions: The solubility can vary in different pH environments, making buffer solutions ideal for maintaining desired solubility levels during biochemical reactions.

In summary, the solubility of 2-amino-3-methyl-pentanoic acid is influenced by its polar functional groups, environmental conditions, and the nature of the solvents used. These factors make it an important compound in various chemical and biological applications.

Interesting facts

Interesting Facts about 2-Amino-3-methyl-pentanoic Acid

2-Amino-3-methyl-pentanoic acid, commonly known as leucine, is one of the essential amino acids that play a crucial role in various biological processes. Here are several fascinating aspects of this compound:

  • Essential Amino Acid: Leucine is classified as an essential amino acid, meaning that the human body cannot synthesize it on its own and must obtain it through dietary sources, such as meat, dairy, and legumes.
  • Protein Synthesis: It plays a significant role in stimulating protein synthesis in muscle tissue, making it especially important for athletes and individuals involved in resistance training. Studies have indicated that leucine can enhance muscle recovery and promote anabolic processes.
  • Blood Sugar Regulation: Leucine has been shown to help regulate blood sugar levels by stimulating insulin secretion, thereby promoting healthy metabolic functions.
  • Brain Function: Research suggests that leucine may aid in the production of brain neurotransmitters, potentially impacting mood and cognitive functions.
  • Research and Development: Scientists continue to explore the therapeutic potentials of leucine, and it is being investigated for its effects on conditions such as obesity, diabetes, and muscle wasting diseases.

The discovery of leucine's various physiological roles emphasizes the importance of amino acids in nutrition and overall health. As a crucial building block of proteins, leucine not only contributes to growth and repair but also plays a pivotal role in metabolic pathways that sustain life.

As a chemistry student or a scientist, recognizing the multifaceted functionality of leucine can inspire deeper insights into how amino acids shape biological systems and how they can be harnessed for therapeutic purposes.

Synonyms
DL-ISOLEUCINE
443-79-8
2-Amino-3-methylpentanoic acid
DL-Allo-isoleucine
2095501-92-9
L(+)-Isoleucine
2-amino-3-methyl-pentanoic acid
Isoleucine, DL-
3107-04-8
DL-2-Amino-3-methylpentanoic acid
H-DL-allo-Ile-OH
CHEBI:38264
DL-Alloisoleucine
Isoleucine, allo-
Isoleucine, threo-
L-Isoleucine, allo-
L-Isoleucine, threo-
NSC-9958
NSC46708
MFCD00065934
(dl)-isoleucine
Isoleucine #
NSC-206282
Norvaline, threo-
NCGC00181164-01
Norvaline, erythro-
(+/-)-Isoleucine
L-Norvaline, threo-
(+/-)-erythro-form
ISOLEUCINE,(L)
(+/-)-erythro-Isoleucine
SCHEMBL8868
Acetic acid, (R*,R*)-
WLN: QVYZY2&1 -L
L-Isoleucine, non animal origin
2-amino-3-methyl pentanoic acid
FEMA 3295
DTXSID80901480
NSC9958
WLN: QVYZY2&1 -L,ALLO
Pentanoic acid, [S-(R*,R*)]-
Pentanoic acid, [S-(R*,S*)]-
BBL100034
FD3037
NSC206282
STL185601
AKOS000120120
AKOS016051419
DL-Allo-isoleucine (H-DL-xiIle-OH)
CS-W013422
HY-W012706
PB48180
SB75593
.alpha.-Amino-.beta.-methylvaleric acid
AC-24098
AS-49219
DA-62942
SY017751
SY022275
SY022276
SY022277
SY022340
(2r,3r)-2-amino-3-methyl-pentanoic acid
DB-017950
DB-043068
DB-043069
[(2R,3R)-2-amino-3-methylpentanoic acid]
A0212
NS00080659
EN300-19355
SR-01000944853
SR-01000944853-1
BRD-A02232681-001-01-8
Q27117434
Q60662693
Z104473608
B821F6FC-012D-4267-ABE2-AA1F36808C01