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Valine

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Identification
Molecular formula
C5H11NO2
CAS number
72-18-4
IUPAC name
2-amino-3-methyl-butanoic acid
State
State

At room temperature, valine is a solid substance. It is one of the essential amino acids that needs to be ingested from dietary sources, and it is commonly included as a component in protein supplements.

Melting point (Celsius)
298.00
Melting point (Kelvin)
571.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
117.15g/mol
Molar mass
117.1480g/mol
Density
1.2300g/cm3
Appearence

Valine appears as a white crystalline solid. It is typically odorless and is slightly soluble in water. The crystalline form gives it a distinct sharp edge geometry, often appearing as fine granules or powder.

Comment on solubility

Solubility of 2-amino-3-methyl-butanoic acid (C5H11NO2)

2-amino-3-methyl-butanoic acid, commonly known as isoleucine, exhibits notable solubility characteristics that are primarily influenced by its molecular structure. This compound is a branched-chain amino acid, which plays a significant role in its solubility properties.

Key solubility features:

  • Water Solubility: Isoleucine is soluble in water, making it accessible for various biological processes. Its solubility in water generally benefits from the presence of the amino group and the carboxylic acid group.
  • Alcohol Solubility: The compound also shows solubility in alcohols, which facilitates its use in different biochemical applications.
  • Solubility Limitations: While it’s soluble in polar solvents, it may have reduced solubility in non-polar organic solvents due to its polar functional groups.

Overall, its solubility in aqueous environments showcases the significance of amino acids in biological systems, often described as essential for protein synthesis and metabolic processes. As noted, the solubility of isoleucine contributes to its functionality and bioavailability in nutritional contexts.

Interesting facts

Interesting Facts About 2-Amino-3-methyl-butanoic Acid

2-Amino-3-methyl-butanoic acid, commonly known as valine, is one of the twenty essential amino acids that are crucial for human health. Here are some fascinating insights about this compound:

  • Essential Amino Acid: Valine is classified as a branched-chain amino acid (BCAA) along with leucine and isoleucine. It is essential, meaning that the body cannot synthesize it and must obtain it from dietary sources.
  • Dietary Sources: Common foods rich in valine include meat, dairy products, nuts, and legumes. Athletes often incorporate these into their diets to support muscle metabolism and energy production.
  • Role in Protein Synthesis: Valine plays a significant role in muscle growth and repair. It helps to stimulate protein synthesis, making it a popular supplement among those engaged in weight training and endurance sports.
  • Potential Health Benefits: Research suggests that valine may also assist in reducing stress and improving focus. It is believed to play a vital role in regulating blood sugar and maintaining positive nitrogen balance in the body.
  • Biochemical Importance: In the context of biochemistry, valine is involved in the production of energy, particularly during exercise. It acts as a carbon skeleton that can be used to create glucose through gluconeogenesis.
  • Genetic Coding: Valine is encoded by the genetic codons GUU, GUC, GUA, and GUG. This redundancy in the genetic code helps ensure consistent protein synthesis during cellular processes.

In summary, 2-amino-3-methyl-butanoic acid is not merely an organic compound; it is a powerhouse amino acid with vital roles in human health, particularly in muscle maintenance and overall metabolic function. As a key player in supporting athletes and individuals leading an active lifestyle, valine is an important focus of nutritional study and supplementation.

Synonyms
DL-Valine
516-06-3
2-Amino-3-methylbutanoic acid
Valine, DL-
H-DL-Val-OH
FEMA No. 3444
25609-85-2
NSC 9755
MFCD00004267
CCRIS 8604
4CA13A832H
DL-2-Amino-3-methylbutanoic acid
D,L-VALINE
NSC-9755
EINECS 208-220-0
2-Amino-3-methylbutanoic acid, DL-
D,L-VALINE [FHFI]
valin
AI3-18308
DL-.alpha.-Aminoisovaleric acid
CHEBI:27266
DTXSID70859522
NSC76038
Hval
7004-03-7
DL-2-Amino-3-methylbutyric acid
2-Aminoisovaleric acid, DL-
UNII-4CA13A832H
L-(+)-.alpha.-Aminoisovaleric acid
alpha-Aminoisovaleric acid, DL-
(dl)-valine
Valine, DL
(RS)-valine
2-Amino-3-methylbutyric acid, DL-
DL-Val
2Aminoisovaleric acid, DL
DL-2-Aminoisovaleric Acid
DL-Valine, >=97%
SCHEMBL8515
VALINE, (L)
Val-376
WLN: QVYZY1&1
L-Valine, non animal origin
2-Amino-3-methylbutanoicacid
alphaAminoisovaleric acid, DL
CHEMBL11257
WLN: QVYZY1&1 -D
WLN: QVYZY1&1 -L
2Amino3methylbutyric acid, DL
(+/-)-a-Aminoisovaleric acid
(+/-)-VALINE
2Amino3methylbutanoic acid, DL
DTXCID00210026
NSC9755
(+/-)-alpha-Aminoisovaleric acid
(s)-2-amino-3-methylbutanoicacid
DL-Valine, >=97% (TLC)
BCP30283
EDA16824
NSC20654
LMFA01100046
NSC125673
NSC125674
STL194272
AKOS000118926
AKOS016050509
AKOS040764370
D-2-Amino-3-methylbutyric acid; Val
AB02568
AB02570
CS-W013605
FV12174
HY-W012889
NSC-125673
NSC-125674
(+/-)-2-AMINOISOVALERIC ACID
NCGC00159470-03
AC-24062
AS-11670
DA-52615
SY002589
SY002593
2-Amino-3-methylbutanoic acid (DL-valine)
DL-Valine, Vetec(TM) reagent grade, 99%
NS00002500
V0013
(+/-)-2-AMINO-3-METHYLBUTYRIC ACID
EN300-17973
DL-Valine, ReagentPlus(R), >=99.0% (NT)
SR-01000944852
SR-01000944852-1
Q27109943
Z57127382
F2191-0220
Valine; NSC 76038; NSC-76038; NSC76038; Valina
8D785241-1AC3-4C14-8D43-308A8EA5169C
208-220-0