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Serine

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Identification
Molecular formula
C3H7NO3
CAS number
56-45-1
IUPAC name
2-amino-3-hydroxy-propanoic acid
State
State

At room temperature, serine is in a solid state, typically available as a powder or crystalline form. It is a polar amino acid which makes it highly soluble in water.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.00
Boiling point (Celsius)
309.00
Boiling point (Kelvin)
582.00
General information
Molecular weight
105.09g/mol
Molar mass
105.0930g/mol
Density
1.6040g/cm3
Appearence

Serine appears as white crystalline solid or powder under standard conditions. It is often utilized in its enantiomerically pure form as L-serine in biological contexts, where it is a constituent of proteins.

Comment on solubility

Solubility of 2-amino-3-hydroxy-propanoic acid (C3H7NO3)

2-amino-3-hydroxy-propanoic acid, commonly known as L-threonine, exhibits good solubility in water, making it an essential amino acid in biochemistry.

  • Highly soluble: L-threonine can easily dissolve in water due to its polar amino group and hydroxyl group, which interact favorably with water molecules.
  • pH dependence: Its solubility can be influenced by the pH of the solution, with greater solubility observed in acidic or neutral environments.
  • Comparison with other amino acids: Among amino acids, L-threonine's solubility is comparable to that of aspartic acid but significantly higher than that of almost any other non-polar amino acids.

Because of its hydrophilic nature, this compound is easily absorbed in the digestive tract and readily participates in biochemical reactions, especially protein synthesis. The solubility characteristics of 2-amino-3-hydroxy-propanoic acid are critical for its functions in biological systems, influencing processes ranging from metabolism to cellular structure formation.

Interesting facts

Exploring 2-Amino-3-hydroxypropanoic Acid

2-amino-3-hydroxypropanoic acid, commonly known as serine, is an intriguing amino acid that plays several vital roles in biochemistry. As a non-essential amino acid, our bodies can synthesize it, yet it is also present in various food sources.

Key Features

  • Biological Significance: Serine is crucial for the synthesis of proteins and is involved in the metabolism of fat and fatty acids.
  • Neurotransmitter Precursor: It serves as a precursor for the synthesis of important neurotransmitters, including glycine and tryptophan.
  • Role in Cellular Functions: Serine is essential for cellular functions, including cell signaling and phospholipid synthesis, which are critical for cell membranes.

In addition to its biological roles, serine is a key component in numerous metabolic pathways, highlighting its versatility and importance in human health.

Applications in Science and Medicine

  • Research: Scientists study serine for its potential therapeutic applications, particularly in neurodegenerative diseases.
  • Dietary Source: It can be found abundantly in foods such as soy products, meat, eggs, and dairy, making it accessible for those who need to boost their intake.
  • Biotechnology: In genetic engineering, serine is crucial in the synthesis of recombinant proteins, which are used for therapeutic applications.

Serine is not just a mundane molecule; it is a cornerstone of life, influencing many biochemical pathways. As the famous saying goes, “Life is chemistry,” and 2-amino-3-hydroxypropanoic acid is a testament to that idea!

Synonyms
DL-Serine
302-84-1
2-Amino-3-hydroxypropanoic acid
Serine DL-form
Serine, DL-
SERINE, (L)
MFCD00064223
DL-2-Amino-3-hydroxypropionic Acid
serin
L-Serine-2-13c-15N
00PAR1C66F
3-Hydroxyalanine
SERINE, L-[3-3H]
DL-SERINE (1-13C)
NSC-9960
(+/-)-2-Amino-3-hydroxypropionic acid
H-DL-Ser-OH
L-Serine-3,3-d2
.beta.-Hydroxyalanine
d,l-serine
UNII-00PAR1C66F
CCRIS 5422
NSC118365
Propanoic acid, 2-amino-3-hydroxy-
L-SERINE (2-13C)
2-Amino-3-hydroxy-propionic acid
NSC 9960
EINECS 206-130-6
DL-Serine, 99%
DL-SERINE [FCC]
bmse000222
SCHEMBL1774
Ser-240
NCIOpen2_000684
DL-SERINE [WHO-DD]
L-Serine, non animal origin
DL-HOCH2CH(NH2)COOH
SERINE DL-FORM [MI]
DL-Serine, analytical standard
CHEBI:17822
DTXSID70859325
NSC9960
DL-Serine, >=98% (TLC)
BCP06311
HY-Y0507
BBL012102
LMFA01100045
NSC620355
s5545
STK125543
AKOS000120985
AKOS016050524
AKOS024264603
CCG-266039
FS38372
NSC-620355
PB42509
AC-24074
AS-10813
SY003812
SY005114
.alpha.-Amino-.beta.-hydroxypropionic acid
DB-047742
DL-Serine, Vetec(TM) reagent grade, 98%
CS-0015292
NS00002236
EN300-18223
C00716
D70822
L001012
SR-01000075474
SR-01000075474-2
Q26997410
Z57396986
F1652-0637
86DE1CCF-D642-4822-9B51-508B465A7DEC
L-2-Amino-3-hydroxypropionic acid; 3-Hydroxy-alanine;(S)-2-amino-3-hydroxypropanoic acid
DL-Serine, BioReagent, suitable for cell culture, suitable for insect cell culture, >=98% (HPLC)