Skip to main content

Threonine

ADVERTISEMENT
Identification
Molecular formula
C4H9NO3
CAS number
72-19-5
IUPAC name
2-amino-3-hydroxy-butanedioic acid
State
State

At room temperature, threonine is in a solid state, typically manifesting as crystalline powder.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
240.00
Boiling point (Kelvin)
513.15
General information
Molecular weight
119.12g/mol
Molar mass
119.1190g/mol
Density
1.6720g/cm3
Appearence

Threonine typically appears as a colorless or white crystalline solid, which is characteristic of many amino acids. These crystals are usually odorless and can exhibit a somewhat bitter taste.

Comment on solubility

Solubility of 2-amino-3-hydroxy-butanedioic acid (C4H9NO3)

2-amino-3-hydroxy-butanedioic acid, commonly known as aspartic acid, exhibits notable solubility characteristics that are important for its applications in various fields. Here are some key points regarding its solubility:

  • Water Solubility: Aspartic acid is highly soluble in water, primarily due to its polar carboxylic acid groups and amino group, which can interact favorably with water molecules.
  • Temperature Sensitivity: The solubility tends to increase with temperature, meaning that higher temperatures can facilitate a greater dissolution of the compound.
  • pH Dependence: The solubility is also pH-dependent; it tends to be more soluble in acidic or basic conditions compared to neutral pH levels, due to ionization of its functional groups.

These attributes make aspartic acid readily available for biological, pharmaceutical, and nutritional applications. In fact, it is often used in the formulation of dietary supplements due to its solubility profile, which enhances its bioavailability in biological systems.

In summary, the solubility of 2-amino-3-hydroxy-butanedioic acid in water and its behavior under varying conditions is a crucial factor that contributes to its widespread use:

  1. High solubility in aqueous solutions
  2. Solubility increases with temperature
  3. Solubility varies with pH

As such, aspartic acid stands out as an important compound in both research and practical applications.

Interesting facts

Interesting Facts about 2-amino-3-hydroxy-butanedioic acid

2-amino-3-hydroxy-butanedioic acid, commonly known as aspartic acid, is a fascinating compound not only due to its essential role in biochemistry but also for its diverse applications in various fields. Here are some noteworthy aspects:

  • Role in Proteins: Aspartic acid is one of the 20 standard amino acids and is crucial for protein synthesis. It is incorporated into proteins via peptide bonds, contributing significantly to the structure and function of enzymes.
  • Neurotransmitter: This compound functions as a neurotransmitter in the brain, playing a vital role in neurotransmission and helping in the communication between nerve cells.
  • Natural Presence: Aspartic acid is found in various food sources, such as sugarcane and molasses, making it readily available for human consumption and absorption.
  • Immune System Support: Research indicates that aspartic acid supports the immune system by aiding in the metabolism of nitrogen and potentially enhancing immune responses.
  • Conversion to Other Amino Acids: It can be converted into other amino acids, such as asparagine, via a simple enzymatic reaction, showcasing its versatility in metabolism.
  • Sweetness: Interestingly, an ester derivative known as aspartame, made from aspartic acid, is used as an artificial sweetener in many diet foods and beverages.

As you can see, 2-amino-3-hydroxy-butanedioic acid is not just a simple molecule; it is fundamental to life, influencing both physiological processes and nutrition. As scientists continue to study its properties, even more benefits and uses may come to light, further solidifying its importance in both health and industry.

Synonyms
3-Hydroxyaspartic acid
71653-06-0
2-Amino-3-hydroxysuccinic Acid
2-amino-3-hydroxybutanedioic acid
d,l-threo-3-HYDROXYASPARTIC ACID
Aspartic acid, 3-hydroxy-
Malic acid, 3-amino-
3-aminomalic acid
beta-Hydroxyaspartic acid
4294-45-5
NSC618260
1860-87-3
CHEBI:83981
3-Hydroxy-DL-aspartic acid
99A78V5YX2
DL-Threo-.beta.-hydroxyaspartic acid
NSC-84663
L-(-)-threo-3-Hydroxyaspartic acid
NSC 139979;threo-beta-Hydroxy-L-aspartic acid
5753-30-0
threo-beta-Hydroxyaspartate
threo-3-Hydroxy-L-aspartic acid
NSC-139979
NSC-158205
2-amino-3-hydroxy-butanedioic acid
EINECS 275-771-1
MFCD00128126
NSC 84663
(2R,3R)-2-Amino-3-hydroxy-butanedioic acid
Spectrum_001134
D -(+)-THREO -BETA-HYDROXYASPARTIC ACID
3-hydroxy-aspartic acid
(2R,3S)-2-AMINO-3-HYDROXY-SUCCINIC ACID
Spectrum2_001914
Spectrum3_001123
Spectrum4_001967
Spectrum5_000765
Aspartic acid, DL-erythro-
DL-Aspartic acid, erythro-
BSPBio_002585
KBioGR_002438
KBioSS_001614
SPECTRUM501000
beta-Hydroxy-DL-aspartic acid
SCHEMBL336363
UNII-99A78V5YX2
SPBio_001908
erythro-3-Hydroxy-DL-aspartate
CHEMBL3039080
KBio2_001614
KBio2_004182
KBio2_006750
KBio3_002085
DTXSID20875575
YYLQUHNPNCGKJQ-UHFFFAOYSA-N
NSC84663
.beta.-erythro-Hydroxy-DL-aspartate
CCG-38483
NSC119128
NSC119129
NSC139979
NSC158204
NSC158205
AKOS022145819
DL-ASPARTIC ACID, 3-HYDROXY-
DL-erythro-.beta.-Hydroxyaspartic acid
NSC-119128
NSC-119129
NSC-158204
NSC-618260
SDCCGMLS-0066971.P001
.BETA.-HYDROXY-DL-ASPARTIC ACID
erythro-.beta.-Hydroxy-DL-aspartic acid
NCGC00015504-02
NCGC00095968-01
AS-87846
D-Aspartic acid,3-hydroxy-, (3R)-rel-
DB-050999
CS-0206811
H0947
D90978
D-Aspartic acid,3-hydroxy-, (3R)- Catalog NuMber
Q27157362