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AMPA

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Identification
Molecular formula
C7H8N2O3
CAS number
74341-63-2
IUPAC name
2-amino-3-(5-methyl-3-oxo-isoxazol-4-yl)propanoic acid
State
State

At room temperature, AMPA is typically a solid substance.

Melting point (Celsius)
271.00
Melting point (Kelvin)
544.15
Boiling point (Celsius)
292.00
Boiling point (Kelvin)
565.15
General information
Molecular weight
169.16g/mol
Molar mass
169.1560g/mol
Density
1.5000g/cm3
Appearence

2-Amino-3-(5-methyl-3-oxo-isoxazol-4-yl)propanoic acid appears as a white crystalline powder.

Comment on solubility

Solubility of 2-amino-3-(5-methyl-3-oxo-isoxazol-4-yl)propanoic acid

The compound 2-amino-3-(5-methyl-3-oxo-isoxazol-4-yl)propanoic acid (C7H8N2O3) exhibits interesting solubility characteristics that can be influenced by its molecular structure.

Key Points on Solubility:

  • Polar Nature: The presence of amino and carboxylic acid functional groups in this compound often leads to a higher polarity, which can enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the -NH2 and -COOH groups contributes significantly to its solubility in aqueous environments.
  • Organic Solvents: While it may have moderate solubility in water, the compound can also show varying degrees of solubility in organic solvents depending on their polarity.
  • Temperature Effect: Solubility may increase with temperature, a common phenomenon for many organic compounds.

In summary, this compound is likely to be more soluble in polar solvents than in non-polar solvents, making it suitable for specific applications where solubility plays a critical role. Understanding these solubility properties is vital for harnessing its potential in various chemical processes.

Interesting facts

Exploring 2-amino-3-(5-methyl-3-oxo-isoxazol-4-yl)propanoic acid

This intriguing compound, known as 2-amino-3-(5-methyl-3-oxo-isoxazol-4-yl)propanoic acid, presents a unique combination of structural attributes and potential applications that make it a subject of interest in both organic chemistry and medicinal research.

Chemical Structure Highlights

The structure of this compound showcases a fascinating blend of amino acids and isoxazole rings, which contributes to its functional diversity. Here are some notable features:

  • Amino Acids: As an amino acid derivative, it plays a significant role in various biochemical processes.
  • Isoxazole Moiety: The presence of the isoxazole ring is notable for its biological activities, particularly in pharmacology.
  • Functional Groups: The combination of the amino group and carboxylic acid functional groups allows for a variety of interactions in biological systems.

Potential Applications

This compound is not just a synthetic curiosity; it may have significant implications in various fields:

  • Pharmaceutical Development: Its structural features suggest potential as a lead compound in drug discovery efforts targeting neurological disorders.
  • Study of Biological Pathways: The incorporation of the isoxazole group can influence protein interactions, which is vital for understanding metabolic pathways.
  • Research into Neurotransmitters: Compounds influenced by similar structures are often studied for their effects on neurotransmitter systems.

Conclusion

In summary, 2-amino-3-(5-methyl-3-oxo-isoxazol-4-yl)propanoic acid exemplifies the complexity and potential of chemical compounds at the intersection of organic synthesis and biological activity. As research continues to unfold, this compound may reveal new avenues for therapeutic advancements and a deeper understanding of chemical interactions in biological systems.

Synonyms
ampa
77521-29-0
(RS)-AMPA
74341-63-2
(R,S)-AMPA
alpha-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
AMPA (pharmaceutical)
CHEMBL13378
2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid
CHEBI:34018
4-Isoxazolepropanoic acid, a-amino-2,3-dihydro-5-methyl-3-oxo-
alpha-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid
(+/-)-AMPA
(R,S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
J090588E6X
AMPA HYDRATE
(R,S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
AMPA hydrobromide
(+/-)-alpha-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
2-amino-3-(5-methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid
2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid
[3H]AMPA
C7H10N2O4
(R)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid
(S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid
GNF-Pf-2579
UNII-J090588E6X
4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-
(R,S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicAcid-13C2,15N
MFCD00069214
(+/-)-alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid Hydrate
gamma-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid
dl-alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
(+-)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
alpha-Amino-2,3-dihydro-5-methyl-3-oxoisoxazolepropionic acid
D,L-alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
AMPA [MI]
(R,S) AMPA
AMPA, D,L-
Lopac0_000581
SCHEMBL68799
GTPL4077
GTPL4131
DTXSID20868301
UUDAMDVQRQNNHZ-UHFFFAOYSA-N
(rs)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
HMS3266A13
HMS3411A07
HMS3675A07
ZCA34163
20 - Acid Herbicides in Wastewater
4-Isoxazolepropanoic acid, .alpha.-amino-2,3-dihydro-5-methyl-3-oxo-
BDBM50002370
HB0030
MFCD00213388
PDSP1_001835
PDSP2_001818
08 - Acid Herbicides in Clean Water
AKOS017343917
AKOS027250886
AB02804
CCG-204670
HY-100815B
SB38931
SB38934
SDCCGSBI-0050563.P002
NCGC00015458-04
NCGC00015458-05
NCGC00024481-03
AS-88012
DA-02875
DB-016844
CS-0021074
NS00114216
M01253
L000026
SR-01000075447-3
BRD-A34716233-001-02-3
BRD-A34716233-004-03-5
Q66370552
( )-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
2-amino-3-(5-methyl-3-oxo-isoxazol-4-yl)propanoic acid
2-ammonio-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoate
2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)-propionic acid
2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid
(R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-propionic acid
(RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionicacid
.alpha.-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid
.GAMMA.-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID
2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID
(+/-)-.ALPHA.-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid(DL-AMPA)
DL-.ALPHA.-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID
110592-37-5