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Identification
Molecular formula
C11H14NO4P
CAS number
22224-92-6
IUPAC name
2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid
State
State

At room temperature, this compound is solid.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
332.00
Boiling point (Kelvin)
605.15
General information
Molecular weight
317.30g/mol
Molar mass
317.2980g/mol
Density
1.3100g/cm3
Appearence

2-Amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid

The solubility of 2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid (C11H14NO4P) is an intriguing aspect to consider, especially due to the presence of both amino and phosphonic acid functional groups in its structure.

Key points about the solubility:

  • Polar Nature: The inclusion of the phosphonic acid moiety contributes to an increased polarity, which often enhances solubility in polar solvents such as water.
  • Amino Group: The amino group can engage in hydrogen bonding, further aiding in its aqueous solubility.
  • Solvent Compatibility: It is likely to be soluble in a variety of solvents, including:
    1. Water
    2. Alcohols
    3. Dimethyl sulfoxide (DMSO)
    4. Acids and Bases

Moreover, it is important to note that the specific solubility can be influenced by factors such as:

  • Temperature: Higher temperatures may increase solubility.
  • pH Levels: Depending on the pH of the solution, the ionization state of the amino and phosphonic groups can significantly alter solubility.

In conclusion, the solubility of 2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid is expected to be relatively high in polar solvents, driven by its functional groups and structural characteristics.

Interesting facts

Interesting Facts about 2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid

The compound 2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid is a fascinating molecule with unique properties and applications in various fields. Below are some interesting insights and facts about this compound:

  • Phosphonic Acid Derivative: This compound belongs to the family of phosphonic acids, which are characterized by the presence of a carbon-phosphorus (C-P) bond. Such compounds are known for their ability to mimic natural substances, making them relevant in pharmaceuticals and agriculture.
  • Biological Relevance: Due to its structural features, this compound can serve as a valuable bioisostere of amino acids, potentially influencing biochemical pathways and processes. It could be explored for its interactions with enzymes or receptors in living organisms.
  • Applications in Drug Development: The unique arrangement of amino and phosphonate groups may enhance its suitability as a lead compound in drug formulation. Researchers often investigate such compounds for their potential neuroprotective effects and antimicrobial properties.
  • Structure-Activity Relationships (SAR): Understanding the SAR of this compound can provide insights into which structural modifications lead to increased biological activity, thus guiding the development of new therapeutics.
  • Research Significance: The exploration of this compound in the laboratory can yield important findings regarding the interaction of phosphonic acids with biological systems, enhancing our understanding of their utility in medicinal chemistry.

In conclusion, 2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid exemplifies the intersection of chemistry and biology, offering numerous avenues for research and application. Its role as a phosphonic acid derivative opens doors to further study in the realms of medicinal chemistry and biochemistry.

Synonyms
PMBA
Phenylbenzene-omega-phosphono-alpha-amino acid
2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid
146533-86-0
3-[2'-Phosphonomethyl[1,1'-biphenyl]-3-yl]alanine
2-amino-3-{3-[2-(phosphonomethyl)phenyl]phenyl}propanoic acid
Lopac0_001008
GTPL4289
CHEMBL1416659
DTXSID201017650
HMS3263I17
Tox21_501008
CCG-205088
LP01008
SDCCGSBI-0050981.P002
NCGC00015789-02
NCGC00015789-03
NCGC00015789-04
NCGC00094301-01
NCGC00094301-02
NCGC00261693-01
EU-0101008
P-204
SR-01000075469
SR-01000075469-1
Q27088420
2-Amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propionic acid