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Tryptophan

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Identification
Molecular formula
C11H12N2O2
CAS number
73-22-3
IUPAC name
2-amino-3-(1H-indol-3-yl)propanoic acid
State
State

At room temperature, tryptophan exists in a solid state, typically as a crystalline powder.

Melting point (Celsius)
289.00
Melting point (Kelvin)
562.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
204.23g/mol
Molar mass
204.2280g/mol
Density
1.3400g/cm3
Appearence

Tryptophan typically appears as an off-white crystalline powder when isolated. In its pure form, it is often colorless or white. It does not have any distinct odor.

Comment on solubility

Solubility of 2-amino-3-(1H-indol-3-yl)propanoic acid (C11H12N2O2)

The solubility of 2-amino-3-(1H-indol-3-yl)propanoic acid is an intriguing topic due to its unique structure and potential applications. This compound exhibits varying solubility characteristics in different solvents:

  • Water: The solubility in water can be influenced by factors such as pH and temperature. Generally, amino acids and their derivatives like this one tend to have moderate solubility in water due to their polar functional groups.
  • Organic solvents: While it may show limited solubility in non-polar solvents, it is expected to be more soluble in polar organic solvents such as methanol or ethanol.
  • Concentration effects: Increasing concentrations of this compound might lead to supersaturation in aqueous solutions, affecting its overall solubility.

Understanding the solubility of this compound is crucial for its applications in pharmaceutical formulations, where solubility can significantly affect bioavailability. As emphasized in various studies, "solubility is one of the primary factors influencing the efficacy of drug delivery systems." Thus, the precise conditions under which 2-amino-3-(1H-indol-3-yl)propanoic acid achieves optimal solubility should be explored in greater detail.

Interesting facts

Interesting Facts about 2-amino-3-(1H-indol-3-yl)propanoic acid

2-amino-3-(1H-indol-3-yl)propanoic acid, often referred to in the scientific community as a derivative of tryptophan, is a fascinating compound due to its structural complexity and biological implications. Here are some notable points regarding this intriguing compound:

  • Biological Significance: It functions as an important intermediate in the biosynthesis of several *neurotransmitters* and *hormones*, playing a vital role in the regulation of mood and cognition.
  • Indole Structure: The presence of the indole ring in its structure contributes to its potential interactions within biological systems, as indole derivatives are often involved in *cell communication* and *signaling pathways*.
  • Potential Neuroprotective Effects: Preliminary studies suggest that compounds like 2-amino-3-(1H-indol-3-yl)propanoic acid may exhibit *neuroprotective properties*, making them of interest for neurological research.
  • Amino Acid Sequence: Being an amino acid, it has implications in the synthesis of proteins, highlighting its role in *cellular metabolism* and *function*.
  • Research Applications: This compound is under investigation in fields such as pharmacology and toxicology due to its potential therapeutic benefits, which opens avenues for further research in drug development.

Scientists are continually researching the properties and effects of this compound, determining how it can be utilized in various applications. Given the intricate relationship between structure and function in biochemistry, 2-amino-3-(1H-indol-3-yl)propanoic acid serves as a vital link in understanding *molecular biology* and *biochemistry* more broadly. As we dive deeper into our understanding of such compounds, the potential for discovering new *therapeutics* and enhancing *human health* is immeasurable.

Synonyms
DL-Tryptophan
54-12-6
2-amino-3-(1H-indol-3-yl)propanoic acid
Racemic Tryptophan
DL-Trytophane
DL-Trytophan
(+-)-Tryptophan
H-DL-Trp-OH
DL-tryptophane
DL-3beta-Indolylalanine
Tryptophan, DL
TRYPTOPHAN, DL-
CCRIS 719
NSC 13118
d,l-tryptophan
EINECS 200-194-9
DL-alpha-Amino-3-indolepropionic acid
DTXSID0021418
AI3-24395
X9U7434L7A
MFCD00064339
NSC-13118
DL-TRYPTOPHAN [FCC]
DTXCID401418
27813-82-7
CHEBI:27897
(+/-)-2-Amino-3-(3-indolyl)propionic acid
NSC13119
DL-.alpha.-Amino-3-indolepropionic acid
(+/-)-alpha-Amino-3-indolepropionic acid
Htrp
DL-Tryptophan, >=99% (HPLC)
beta-3-indolylalanine
SR-01000597138
DLTrytophane
UNII-X9U7434L7A
Tryptophan; N-Acetyltryptophan Imp. A (EP); N-Acetyltryptophan Impurity A
Propionic acid, 2-amino-3-indol-3-yl
DL-2-Amino-3-indolepropionic acid
80206-30-0
DL3betaIndolylalanine
(+/-)-Tryptophan
DL-3A-Indolylalanine
Spectrum_000087
(R)-2-amino-3-(1H-indol-3-yl)propanoic acid
Spectrum2_001102
Spectrum3_001379
Spectrum4_000579
Spectrum5_001310
(.+/-.)-Tryptophan
(r)-(+)l-trp
SCHEMBL7327
NCIOpen2_006535
BSPBio_002938
KBioGR_001018
KBioSS_000507
SPECTRUM1500600
SPBio_001204
a-amino-3-indolepropionic acid
CHEMBL484901
SCHEMBL19161120
ACon1_001815
DLalphaAmino3indolepropionic acid
KBio2_000507
KBio2_003075
KBio2_005643
KBio3_002158
HMS1648B01
HMS1921I11
HMS2092A20
202406-50-6
ALBB-007460
GDA20192
NSC13118
WLN: T56 BMJ D1YZVQ -L
Tox21_202793
BBL004467
CCG-40280
NSC122286
STK029637
2-amino-3-(3-indolyl)propionic acid
AKOS000118922
AKOS016038053
L-Tryptophan , from non-animal origin
CS-W013196
FT09075
HY-W012480
NSC-122286
SB14995
SB14996
SB14997
SDCCGMLS-0066645.P001
alpha-amino-beta-3-indolepropionic acid
CAS-54-12-6
NCGC00015994-02
NCGC00015994-03
NCGC00015994-04
NCGC00015994-05
NCGC00015994-06
NCGC00015994-09
NCGC00015994-10
NCGC00015994-12
NCGC00094805-01
NCGC00094805-02
NCGC00094805-03
NCGC00094805-04
NCGC00260339-01
2-amino-3-(1H-indol-3-yl)propanoicacid
AC-24066
AS-11002
BP-12575
NCI60_000685
SY010557
SY011477
SY012692
SBI-0051549.P002
DB-002704
2-amino-3-(1H-indol-3-yl)-propionic acid
alpha-Amino-beta-(3-indolyl)-propionic acid
DL-Tryptophan, puriss., >=99.0% (NT)
NS00078848
T0540
EN300-18165
VU0243366-4
C00806
D70570
DL-Tryptophan, Vetec(TM) reagent grade, 98%
(+/-)-2-AMINO-3-INDOLYLPROPANOIC ACID
AB00052121-04
L023952
SR-01000597138-1
SR-01000597138-2
SR-01000597138-3
5D88F09F-FA0E-488B-BEC6-DDDC859A7A29
BRD-A07106394-001-02-5
Q27103394
Q27115092
Z57248626
F3145-2942
L-TRYPTOPHAN-13C11 15N2 97 ATOM % 13C&
200-194-9
InChI=1/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15