Skip to main content

Histidine

ADVERTISEMENT
Identification
Molecular formula
C6H9N3O2
CAS number
71-00-1
IUPAC name
2-amino-3-(1H-imidazol-5-yl)propanal
State
State

At room temperature, histidine is a solid. It is mostly found in crystalline form which makes it easier to handle in research and industrial applications.

Melting point (Celsius)
282.00
Melting point (Kelvin)
555.15
Boiling point (Celsius)
246.00
Boiling point (Kelvin)
519.15
General information
Molecular weight
155.15g/mol
Molar mass
155.1540g/mol
Density
1.2100g/cm3
Appearence

Histidine is typically a white, crystalline powder. It is hygroscopic and can appear slightly off-white when it absorbs moisture from the environment.

Comment on solubility

Solubility of 2-amino-3-(1H-imidazol-5-yl)propanal

2-amino-3-(1H-imidazol-5-yl)propanal, with the chemical formula C6H9N3O2, demonstrates interesting solubility characteristics that are influenced by its functional groups and overall structure.

Key points regarding solubility:

  • Polar Nature: The presence of amino (–NH2) and hydroxyl (–OH) functional groups enhances its potential for solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to engage in hydrogen bonding facilitates increased solubility in aqueous environments.
  • pH Sensitivity: The solubility of the compound may vary with pH due to the protonation and deprotonation of the amino group, which can affect its interaction with water molecules.
  • Solvent Compatibility: While it is expected to be more soluble in polar solvents, it may exhibit varying degrees of solubility in organic solvents depending on their polarity.

In summary, the solubility of 2-amino-3-(1H-imidazol-5-yl)propanal is largely governed by its polar structure, enabling it to dissolve well in aqueous solutions while exhibiting sensitivity to environmental conditions such as pH.

Interesting facts

Interesting Facts about 2-amino-3-(1H-imidazol-5-yl)propanal

2-amino-3-(1H-imidazol-5-yl)propanal, often simply referred to as an imidazole derivative, is a fascinating compound in the field of organic chemistry. Here are some noteworthy aspects of this compound:

  • Biological Significance: This compound is related to important biological pathways and is often studied for its potential role in various metabolic processes.
  • Structural Features: The presence of both an amino group and an imidazole ring contributes to its diverse properties, making it a potential candidate for various applications in biochemistry.
  • Pharmacological Potential: Due to its structure, 2-amino-3-(1H-imidazol-5-yl)propanal can exhibit significant activity against certain biological targets, indicating its potential as a lead compound in drug discovery.
  • Research Applications: This compound has been utilized in research involving protein interactions and enzyme mechanisms, highlighting its versatile nature in experimental setups.

Furthermore, derivatization of the imidazole ring can lead to a vast array of new compounds, enriching the synthetic landscape. It is often the focus of educational discussions, emphasizing the connectivity between structure and function in organic molecules. As highlighted in one study, "the diversity in heterocyclic chemistry opens pathways to innovative therapeutic solutions."

In summary, 2-amino-3-(1H-imidazol-5-yl)propanal not only presents intriguing chemical properties but also serves as a valuable compound in the realms of biology and pharmacology, making it a central topic of discussion and research in contemporary chemistry.

Synonyms
BAY-o-6997
omega-formyl histamine
SCHEMBL234364
SCHEMBL12652228
AKOS006352677
(S)-2-amino-3-(1H-imidazol-4-yl)propanal