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Histidinol

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Identification
Molecular formula
C6H11N3O
CAS number
500-98-1
IUPAC name
2-amino-3-(1H-imidazol-5-yl)propan-1-ol
State
State

At room temperature, histidinol is typically in a solid crystalline state.

Melting point (Celsius)
252.00
Melting point (Kelvin)
525.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
126.17g/mol
Molar mass
126.1570g/mol
Density
1.3420g/cm3
Appearence

Histidinol is a crystalline solid that appears white or almost white in color. It is generally odorless and is available in the form of needles or elongated prisms.

Comment on solubility

Solubility of 2-amino-3-(1H-imidazol-5-yl)propan-1-ol (C6H11N3O)

The solubility of 2-amino-3-(1H-imidazol-5-yl)propan-1-ol (often referred to as a bioactive compound) can be described as follows:

  • Polar Nature: Due to the presence of amino (-NH2) and hydroxyl (-OH) functional groups, this compound is highly polar.
  • Hydrogen Bonding: The ability to form hydrogen bonds enhances its solubility in polar solvents, notably water.
  • Solvent Compatibility: It tends to be less soluble in non-polar solvents such as hexane or toluene due to the mismatch in polarity.
  • pH Sensitivity: The solubility may vary with pH, as altering the protonation of the imidazole nitrogen can affect its interactions with the solvent.

Furthermore, it is noteworthy to mention that "solubility" can vary depending on temperature and the specific concentration of the solute in the solution. As with many compounds, **the degree of solubility may be practically determined experimentally** rather than only theoretically predicted. In conclusion, 2-amino-3-(1H-imidazol-5-yl)propan-1-ol exhibits promising solubility characteristics in favorable environments, making it a compound of interest in various chemical and pharmaceutical applications.

Interesting facts

Interesting Facts About 2-Amino-3-(1H-Imidazol-5-yl)propan-1-ol

2-Amino-3-(1H-imidazol-5-yl)propan-1-ol, commonly referred to as a derivative of amino alcohols, exhibits fascinating characteristics that make it a compound of great interest in the field of chemistry and biochemistry.

Key Features

  • Biological Significance: This compound serves as a crucial building block in the synthesis of various pharmacologically active substances. Its structural elements can participate in medicinal chemistry and drug development, notably in creating therapeutic agents.
  • Imidazole Ring: The presence of the imidazole ring is noteworthy; it is a critical component found in many biomolecules, including histidine, a vital amino acid involved in multiple enzyme reactions within the body.
  • Reactivity: The amino group (-NH2) in this compound is reactive and can participate in various chemical reactions, making it a versatile intermediate in organic synthesis.
  • Possible Applications: Its unique structure suggests potential applications in areas such as antioxidants, antimicrobials, and anti-inflammatory agents.

Chemical Interactions

The chemical interactions of this compound can lead to fascinating phenomena. For example, it could engage in hydrogen bonding due to the presence of both the hydroxyl and amino groups, influencing its solubility and reactivity with other compounds. This behavior makes it essential for the study of reaction mechanisms and molecular interactions.

Current Research

Recent studies have focused on the exploration of 2-amino-3-(1H-imidazol-5-yl)propan-1-ol in the context of drug discovery. Researchers are eager to uncover its potential roles in designing new therapeutic agents targeting various pathways in diseases, particularly in neuropharmacology and oncology.

In summary, 2-amino-3-(1H-imidazol-5-yl)propan-1-ol represents a remarkable compound that offers numerous avenues for exploration in both chemistry and biological sciences, proving that even simple structures can hold substantial promise for significant discoveries.

Synonyms
histidinol
501-28-0
2-amino-3-(1H-imidazol-5-yl)propan-1-ol
1H-Imidazole-4-propanol, beta-amino-
CCRIS 555
DTXSID70880033
histidol
DL-Histidinol Dihydrochloride
NSC611347
2-amino-3-(1H-imidazol-4-yl)propan-1-ol
NCIOpen2_004052
SCHEMBL65204
CHEMBL2007999
DTXCID50812079
ZQISRDCJNBUVMM-UHFFFAOYSA-N
AKOS006222285
NCI60_004839
NCI60_041634
CS-0055745
EN300-170663
(2r)-2-amino-3-(1h-imidazol-5-yl)propan-1-ol
D250F7D9-1B8A-4CEA-BEC9-2C655A4BD9B3
Q50318272
(2S)-1-hydroxy-3-(1H-imidazol-5-yl)propan-2-aminium
1H-Imidazole-5-propanol, .beta.-amino-, (.beta.S)-
2-Amino-3-(1H-imidazol-4-yl)-1-propanol hydrochloride