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Alanine

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Identification
Molecular formula
C3H7NO2
CAS number
302-72-7
IUPAC name
2-amino-2-methyl-propanoic acid
State
State

Alanine is generally found in solid-state at room temperature. This crystalline solid is stable under normal laboratory conditions.

Melting point (Celsius)
295.00
Melting point (Kelvin)
568.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
89.09g/mol
Molar mass
89.0940g/mol
Density
1.4240g/cm3
Appearence

Alanine appears as a white crystalline powder. It is odorless and tasteless, commonly used in biochemical research and analysis.

Comment on solubility

Solubility of 2-amino-2-methyl-propanoic acid

2-amino-2-methyl-propanoic acid, also known as isoleucine, has interesting solubility characteristics:

  • It is generally considered soluble in water due to its polar functional groups.
  • The presence of the amino group amplifies its ability to interact favorably with water molecules.
  • Its solubility varies with temperature and pH of the solvent:
    • As temperature increases, solubility tends to improve for many amino acids.
    • At different pH levels, the amino acid may exist in different ionic forms, affecting solubility.

In terms of compatibility with organic solvents, 2-amino-2-methyl-propanoic acid exhibits significantly lower solubility, making it primarily an aqueous compound. Thus, it is predominantly encountered in biological and aqueous environments.

To summarize, 2-amino-2-methyl-propanoic acid showcases commendable water solubility properties, influenced by various environmental factors, making it a versatile compound in biochemical applications.

Interesting facts

Interesting Facts about 2-Amino-2-Methyl-Propanoic Acid

2-Amino-2-methyl-propanoic acid, often known as α-aminoisobutyric acid, is a fascinating organic compound that merges both function and form in the world of chemistry. Here are some engaging facts about this compound:

  • Amino Acid Profile: It is classified as a non-proteinogenic amino acid, meaning it isn't directly incorporated into proteins but still plays vital roles in metabolic processes.
  • Role in Metabolism: This compound is involved in several biochemical pathways, including the metabolism of branched-chain amino acids, thus influencing energy production and muscle health.
  • Chemical Structure: Its unique structure, characterized by a branched chain, contributes to its distinctive properties and functionalities, making it a subject of study in amino acid synthesis.
  • Semi-synthetic Derivatives: Researchers are exploring synthetic derivatives of this compound for their potential benefits in pharmaceuticals and nutraceuticals.
  • Biological Implications: While not widely recognized as an essential amino acid, it has shown promise in neuroprotective applications and is of interest in the study of neurological health.
  • Research Potential: Ongoing studies aim to elucidate its role in various therapeutic applications, particularly relating to metabolism and muscle development.

As we dive deeper into the chemistry of compounds like 2-amino-2-methyl-propanoic acid, we uncover layers of complexity and fascinating biological implications that can enhance our understanding of both chemistry and health.

Synonyms
2-Aminoisobutyric acid
62-57-7
2-Methylalanine
2-Amino-2-methylpropanoic acid
H-Aib-OH
ALPHA-AMINOISOBUTYRIC ACID
Alanine, 2-methyl-
2-Amino-2-methylpropionic acid
alpha-Methylalanine
alpha-Aminoisobutanoic acid
NSC 16590
alpha,alpha-Dimethylglycine
a-Aminoisobutyric acid
2,2-dimethylglycine
AIB
Propionic acid, 2-amino-2-methyl-
a-Aminoisobutyrate
MFCD00008049
2-amino-2-methyl-propanoic acid
.alpha.-Aminoisobutyric acid
2-amino-isobutyric acid
2-Amino-2-methylpropanoate
2-Aminoisobutyrate
EINECS 200-544-0
1E7ZW41IQU
Aminoisobutyric acid
.alpha.-Aminoisobutanoic acid
CB 1637
BRN 0506496
alpha-Aminoisobutyrate
.alpha.-Methylalanine
CHEBI:27971
AI3-15082
NSC-16590
DTXSID0058772
.alpha.,.alpha.-Dimethylglycine
4-04-00-02616 (Beilstein Handbook Reference)
Propanoic acid, 2-amino-2-methyl-
.ALPHA.-AMINOISOBUTYRIC ACID [MI]
Enzalutamide impurity 15
2-aminoisobutyric acid (2-methylalanine)
|A-aminoisobutyric acid
UNII-1E7ZW41IQU
a-Methylalanine
2Methylalanine
alphaMethylalanine
2-methyl alanine
Alanine, 2methyl
a-Aminoisobutanoate
2-methyl-L-alanine
alpha-Aminoisobutanoate
alpha-methyl-l-alanine
2-Aminoisobutyric-acid
a-Aminoisobutanoic acid
a-amino isobutyric acid
alphaaminoisobutyric acid
.alpha.-Aminoisobutyrate
alpha,alphaDimethylglycine
alphaAminoisobutanoic acid
alpha -aminoisobutyric acid
2Amino2methylpropanoic acid
2Amino2methylpropionic acid
SCHEMBL23312
?-AMINOISOBUTYRIC ACID
Propionic acid, 2amino2methyl
WLN: ZX1&1&VQ
2-Aminoisobutyric acid, 98%
CHEMBL1230906
DTXCID4043199
2-amino-2-methyl-propionic acid
CS-B0930
HY-Y0124
NSC16590
AC8052
BBL027672
LMFA01100053
s6270
STK034507
AKOS000195995
AB00918
AC-2694
DB02952
FA02753
NSC-16590;2-Methylalanine;H-Aib-OH
765258-64-8
AS-15790
BP-12097
SY002590
A0323
NS00014649
EN300-53414
A22742
C03665
Q4596860
alpha-Aminoisobutyric acid, puriss., >=99.0% (NT)
5085F756-CF99-4860-BBBD-469F4BDEF53C
F8889-8339
Z317024776
2-Amino-2-methylpropionic acid; alpha-Aminoisobutyric acid; 2-Methylalanine
N-Me-alanine;N-Me-ala-oh; DL-2-Amino-iso-butyric acid;H-2-Aminoisobutyric acid
65503-84-6
857402-27-8