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Arotinolol

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Identification
Molecular formula
C10H9N5O2
CAS number
24143-37-7
IUPAC name
2-amino-2-[4-(2H-tetrazol-5-yl)phenyl]propanoic acid
State
State

The compound is typically in a solid-state at room temperature. It is stable under normal conditions and should be stored in a cool, dry place.

Melting point (Celsius)
278.00
Melting point (Kelvin)
551.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
198.18g/mol
Molar mass
198.1760g/mol
Density
1.3800g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. It is generally odorless and may possess a bitter taste.

Comment on solubility

Solubility of 2-amino-2-[4-(2H-tetrazol-5-yl)phenyl]propanoic acid

The solubility of 2-amino-2-[4-(2H-tetrazol-5-yl)phenyl]propanoic acid (C10H9N5O2) can be elaborated upon by considering several key factors:

  • Polar Functional Groups: This compound contains both amino (-NH2) and carboxylic acid (-COOH) functional groups which typically enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The presence of these groups allows for potential hydrogen bonding with solvent molecules, contributing to a favorable solubility profile.
  • Salt Formation: In acidic conditions, the carboxylic acid can dissociate, leading to the formation of a carboxylate anion which is more soluble in water.
  • Influence of the Tetrazole Ring: The tetrazole moiety may add to hydrophilicity, further promoting solubility due to its nitrogen atoms.

However, precise solubility data can vary based on factors such as temperature and pH. In summary, this compound is generally expected to show reasonable solubility in aqueous solutions, particularly under conditions that favor its ionic form.

Interesting facts

Interesting Facts about 2-Amino-2-[4-(2H-tetrazol-5-yl)phenyl]propanoic Acid

2-amino-2-[4-(2H-tetrazol-5-yl)phenyl]propanoic acid, often abbreviated as a hybrid compound featuring both amino acid and tetrazole functionalities, possesses intriguing characteristics that make it a subject of interest in various fields of research.

Key Features:

  • Biodiversity in Structure: This compound combines a phenyl group with a tetrazole moiety, providing it with enhanced biological activities. Tetrazoles are known for their role in medicinal chemistry, often acting as bioisosteres for carboxylic acids.
  • Pharmaceutical Potential: The presence of both amino and tetrazole groups lends this compound the potential to interact with biological systems, making it a contender for drug development in areas such as neuropharmacology and anti-inflammatory therapies.
  • Versatile Reactivity: The amino group contributes to the compound’s reactivity, allowing for various chemical modifications that can generate derivatives with tailored properties for specific applications in research and industry.
  • Research Applications: This compound has shown promise as an important intermediate in the synthesis of more complex organic molecules, especially in the fields of organic synthesis and materials science.

Noteworthy Comparisons:

Interestingly, researchers have compared similar compounds to 2-amino-2-[4-(2H-tetrazol-5-yl)phenyl]propanoic acid to explore their varying effects in:

  • Antimicrobial activities
  • Cognitive enhancement studies
  • Anti-cancer properties

As aptly stated in scientific literature: "The incorporation of bioactive functional groups assists in fine-tuning the pharmacological profile of designated compounds." This highlights the significance of hybrids like 2-amino-2-[4-(2H-tetrazol-5-yl)phenyl]propanoic acid in advancing drug design and molecular biology.

In conclusion, this compound exemplifies the intersection of organic chemistry and pharmacology, inviting ongoing investigation into its diverse applications and functionalities. With continuous research and exploration, compounds like this are set to pave the way for innovative scientific breakthroughs.

Synonyms
MTPG
2-(4-(1H-Tetrazol-5-yl)phenyl)-2-aminopropanoic acid
Benzeneacetic acid, alpha-amino-alpha-methyl-4-(2H-tetrazol-5-yl)-
CHEMBL1594103
SCHEMBL12648708
HMS3266L04
HMS3411P13
HMS3675P13
AKOS022181252
NCGC00024828-02
HY-101247
CS-0021034
SR-01000597428
SR-01000597428-1
2-(4-(1H-Tetrazol-5-yl)phenyl)-2-aminopropanoicacid
BRD-A28329383-001-02-1