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Platelet Activating Factor (PAF)

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Identification
Molecular formula
C24H50NO7P
CAS number
65128-38-3
IUPAC name
(2-acetoxy-3-hexadecanoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate
State
State

At room temperature, this compound is typically found in a liquid state.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
185.00
Boiling point (Kelvin)
458.15
General information
Molecular weight
523.74g/mol
Molar mass
523.7370g/mol
Density
0.9870g/cm3
Appearence

This compound typically appears as a viscous oil.

Comment on solubility

Solubility of (2-acetoxy-3-hexadecanoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate

The solubility characteristics of the compound (2-acetoxy-3-hexadecanoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate (C24H50NO7P) are intriguing, reflecting its complex molecular structure. Here are some considerations regarding its solubility:

  • Hydrophilic and Hydrophobic Regions: The presence of a trimethylammonio group contributes positively to its solubility in polar solvents, while the hexadecanoyl chain gives rise to hydrophobic characteristics.
  • Potential Solvents: This compound is likely more soluble in organic solvents such as methanol and ethanol due to its lipophilic nature, whereas water solubility may be limited.
  • Factors Influencing Solubility: The balance between hydrophilic and hydrophobic segments can significantly affect how this compound interacts with solvents.

In practice, the compound's solubility can be summarized as follows:

  1. May exhibit moderate solubility in polar organic solvents.
  2. Limited solubility in non-polar solvents.
  3. Potential challenges with dissolution in aqueous environments due to hydrophobic chains.

Understanding the solubility behavior of this compound is essential for its applications in various fields, including pharmaceuticals and biochemical research, as it directly affects bioavailability and interaction with biological systems. As stated, "the property of solubility can dictate the effectiveness of a compound in practical applications."

Interesting facts

Interesting Facts about (2-acetoxy-3-hexadecanoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate

This compound belongs to a fascinating class of chemicals known as phospholipids, which play vital roles in biological membranes. Here are some intriguing aspects to consider:

  • Biological Significance: Phospholipids are essential components of cell membranes. They help maintain the structural integrity of cells while also facilitating communication between cells.
  • Surface Activity: Due to its unique amphiphilic nature, this compound can reduce surface tension, making it valuable in various applications such as detergents and emulsifiers.
  • Drug Delivery Systems: The structural properties of (2-acetoxy-3-hexadecanoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate enable it to be used as a carrier for pharmaceuticals, improving their solubility and stability.
  • Bioactivity: It has been studied for its potential effects on cell signaling pathways, helping researchers understand disease mechanisms and develop therapeutic interventions.

Applications in Research:

The unique properties of this compound open avenues for various research applications, including:

  1. Investigation of lipid bilayer dynamics.
  2. Exploration of interactions with proteins and other membrane components.
  3. Development of advanced biomaterials for medical and industrial purposes.

As a scientist or student in the field of chemistry, understanding compounds like (2-acetoxy-3-hexadecanoyloxy-propyl) 2-(trimethylammonio)ethyl phosphate not only broadens knowledge of chemical interactions but also underlines the significance of *molecular structure* in determining functionality and reactivity.

In short, this compound exemplifies how the integration of chemistry with biological systems can yield innovative solutions to complex problems in both science and industry.

Synonyms
115154-33-1
(2-acetyloxy-3-hexadecanoyloxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
1-acyl-PAF
3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide(9CI]
3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide
3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt
CHEMBL164328
CHEBI:183880