Testosterone acetate | Solubility of Things

Identification

Molecular formula

C₂₁H₃₀O₃

CAS number

1045-69-8

IUPAC name

[2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate

State

The compound is typically found in a solid state at room temperature.

Melting point (Celsius)

139.00

Melting point (Kelvin)

412.20

Boiling point (Celsius)

360.70

Boiling point (Kelvin)

633.90

General information

Molecular weight

330.47g/mol

Molar mass

330.4670g/mol

Density

1.0900g/cm³

Appearence

Testosterone acetate appears as a white to practically white crystalline powder. It is odorless and has a faint, characteristic smell, making it almost undetectable by scent.

Comment on solubility

Solubility of 2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate

The solubility of the compound with the formula C₂₁H₃₀O₃ can be described as follows:

General Solubility: This compound is likely to exhibit limited solubility in polar solvents such as water due to its larger hydrophobic regions.
Organic Solvents: It is expected to be more soluble in organic solvents, including:
- Chloroform
- Ethanol
- Acetone
Temperature Dependence: The solubility may also vary with temperature, as increased temperatures often enhance solubility in organic solvents.
pH Effects: The presence of functional groups such as esters might influence solubility in different pH environments, possibly leading to hydrolysis which could modify solubility characteristics.

In summary, while C₂₁H₃₀O₃ may demonstrate limited solubility in aqueous systems, its compatibility with various organic solvents opens avenues for its application in chemical and pharmaceutical formulations. As stated, “the solvent effects are paramount in determining the solubility and bioavailability of compounds.”

Interesting facts

Interesting Facts about 2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate

This complex organic compound is a fascinating example of the interplay between structure and biological activity. Here’s what makes it noteworthy:

Stereochemistry: The intricate stereochemical configuration (with multiple chiral centers) plays a crucial role in determining the compound's biological properties. In medicinal chemistry, stereochemistry is often the key to ensuring the desired effect in drug design.
Biological Activity: Compounds of this nature are often studied for their potential therapeutic effects, particularly in fields like oncology and endocrine regulation. The cyclic structure may contribute to its interactions with biological targets.
Applications in Drug Development: As a derivative related to steroid structures, it could provide insights into the synthesis of new pharmaceuticals, mimicking or inhibiting natural biological processes.
Research Interest: Scientists are drawn to the unique nature of such compounds for their potential roles in synthetic organic chemistry, contributing to innovations in compound synthesis and modification techniques.

In summary, the study of 2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate is a testament to the sophistication and complexity of organic compounds. As you delve into its chemical properties, you can uncover a world of possibilities in both research and practical applications.

Embrace the intricate world of chemistry, where even a single compound can tell a story of its own!

Synonyms

Deoxycorticosterone acetate

56-47-3

DESOXYCORTICOSTERONE ACETATE

DOCA

Desoxycortone acetate

Percotol

Cortexone acetate

Decosteron

Decosterone

Sincortex

DOC acetate

11-Deoxycorticosterone acetate

Decostrate

Descorterone

Docaquosum

Dorcostrin

Krinocorts

Primocortan

Cortacet

Cortate

Cortenil

Cortesan

Cortifar

Cortinaq

Cortiron

Cortivis

Cortixyl

Decorten

Descornaq

Doxatone

Doxycamon

Mincortid

Ocriten

Ocritena

Primocort

Syncorta

Syncortyl

Unidocan

Arcort

Pregn-4-ene-3,20-dione, 21-(acetyloxy)-

Steraq

Deoxycortone acetate

Bio-Corten

Doc-Ac

Desoxykorton

Cortigen

Cortormon

Percortene

Doca acetate

DOXO

Organon's doca acetate

21-Acetoxypregn-4-ene-3,20-dione

Deoxycorticosterone 21-acetate

11-Desoxycorticosterone acetate

Desoxycorticosterone-21-acetate

Corticosterone, deoxy-, acetate

4-Pregnene-3,20-dione-21-ol acetate

11-Deoxycorticosterone 21-acetate

Deoxy Corticosterone Acetate

Decorton

Desocort

Syncort

4-Pregnene-3,20-dione 21-acetate

21-Acetoxy-3,20-diketopregn-4-ene

CCRIS 7517

NSC 9567

EINECS 200-275-9

UNII-6E0A168OB8

21-Hydroxypregn-4-ene-3,20-dione 21-acetate

3,20-Dioxopregn-4-en-21-yl acetate

BRN 2570798

Pregn-4-ene-3,20-dione, 21-hydroxy-, acetate

11-Deoxycorticosterone, acetate

DTXSID6022894

6E0A168OB8

NSC-9567

Deoxycorticosterone (acetate)

MLS000028509

DTXCID102894

CHEBI:34671

Desoxycorticosterone acetate (USP)

Desoxycorticosterone acetate [USP]

4-08-00-02195 (Beilstein Handbook Reference)

Deoxycorticosterone acetate (Standard)

NCGC00022043-04

SMR000058339

Descotone

2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate

DESOXYCORTONE ACETATE (MART.)

DESOXYCORTONE ACETATE [MART.]

CAS-56-47-3

DESOXYCORTONE ACETATE (EP IMPURITY)

DESOXYCORTONE ACETATE [EP IMPURITY]

DOC 21 acetate

DOC-21-acetate

DESOXYCORTICOSTERONE ACETATE (USP-RS)

DESOXYCORTICOSTERONE ACETATE [USP-RS]

Acetate, Desoxycortone

DESOXYCORTICOSTERONE ACETATE (USP IMPURITY)

DESOXYCORTICOSTERONE ACETATE [USP IMPURITY]

11-Deoxycorticosterone acetate;DOC acetate;Cortexone acetate

Deoxycorticosterone 21 acetate

deoxycorticosterone-21-acetate

Desoxycorticosterone 21 acetate

21-Acetoxypregn-4-en-3,20-dione

21-Acetoxy-4-pregnene-3,20-dione

MFCD00003660

21-Acetyloxypregn-4-ene-3,20-dione

Doca (TN)

Opera_ID_47

ST075186

SCHEMBL4169

MLS001074065

MEGxm0_000470

CHEMBL1200542

NIOSH/TU5076000

ACon1_002189

HY-B1472R

Deoxycorticosterone acetate, 98%

HMS2230B14

HY-B1472

Tox21_110876

s4243

AKOS004910359

AKOS015837895

DESOXYCORTONE ACETATE [WHO-DD]

Tox21_110876_1

CCG-268330

CS-5159

DB06780

DEOXYCORTICOSTERONE ACETATE [MI]

NCGC00022043-05

NCGC00022043-06

[2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate

[2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

2-((1S,10S,11S,14S,15S,2R)-2,15-dimethyl-5-oxotetracyclo[8.7.0.0<2,7>.0<11,15> ]heptadec-6-en-14-yl)-2-oxoethyl acetate

AS-11731

3,20-Dioxopregn-4-en-21-yl acetate #

21-Hydroxypregn-4-ene-3,20-dione acetate

DESOXYCORTICOSTERONE ACETATE [VANDF]

CS-0694936

D0047

NS00015396

TU50760000

D03698

D81855

AB00383000_10

DESOXYCORTICOSTERONE ACETATE [ORANGE BOOK]

EN300-19631630

SR-01000000097

21-Hydroxypregn-4-ene-3,20-dione acetate (ester)

SR-01000000097-3

BRD-K24556098-001-01-9

BRD-K24556098-001-16-7

BRD-K24556098-001-17-5

BRD-K24556098-001-19-1

Q27116214

Pregn-4-ene-3,20-dione, 21-hydroxy-, acetate (ester)

Desoxycortone acetate, European Pharmacopoeia (EP) Reference Standard

Deoxycorticosterone acetate, United States Pharmacopeia (USP) Reference Standard

2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethylacetate

2-[(1S,3aS,3bS,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate

200-275-9

21-(Acetyloxy)-pregn-4-ene-3,20-dione;11-Deoxycorticosterone 21-acetate;21-Acetoxy-3,20-diketopregn-4-ene

acetic acid [2-keto-2-[(8S,9S,10R,13S,14S,17S)-3-keto-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]ethyl] ester