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Trolox

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Identification
Molecular formula
C14H18O4
CAS number
53188-07-1
IUPAC name
2-(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)acetic acid
State
State

At room temperature, Trolox is a solid. It is typically handled as a solid powder in laboratory settings.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.00
Boiling point (Celsius)
298.00
Boiling point (Kelvin)
571.00
General information
Molecular weight
250.32g/mol
Molar mass
250.3190g/mol
Density
1.2500g/cm3
Appearence

Trolox appears as a white crystalline powder. It is often used in scientific research and formulations for its antioxidant properties.

Comment on solubility

Solubility of 2-(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)acetic acid

The solubility of 2-(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)acetic acid, with the chemical formula C14H18O4, can be quite interesting and is impacted by several factors. This compound, known for its antioxidant properties, exhibits variable solubility depending on the solvent used.

Key Factors Influencing Solubility

  • Polarity of the Solvent: Being a carboxylic acid, it tends to have increased solubility in polar solvents such as water or alcohols due to hydrogen bonding.
  • Hydrophobic Interactions: The tetramethyl group contributes to hydrophobic characteristics, which may hinder solubility in purely aqueous environments.
  • Temperature: Typically, solubility increases with temperature, so heating the solvent may enhance the dissolution process.

In summary, while 2-(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)acetic acid is expected to be soluble in polar environments, its solubility can be limited by its hydrophobic nature. As one might say, “The balance of polarity is key.”
Thus, for practical applications, it's essential to consider the appropriate solvent to maximize solubility.

Interesting facts

Exploring 2-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)acetic Acid

2-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)acetic acid, often referred to in scientific discussions as a derivative of a powerful antioxidant compound called Trolox, has become a subject of fascination in the fields of biochemistry and pharmacology. This compound is known for its potential health benefits and applications due to its unique structure and properties.

Interesting Facts:

  • Antioxidant Properties: The compound exhibits strong antioxidant activity, which helps to neutralize harmful free radicals in the body. This action is vital for reducing oxidative stress linked to various chronic diseases.
  • Vitamin E Analogue: Because of its structural similarities to Vitamin E, this compound mimics and enhances the actions of this essential nutrient, thereby contributing to cellular health and longevity.
  • Bioavailability: Research indicates that this compound is well-absorbed in the body, making it potentially effective in various therapeutic applications related to oxidative damage and inflammation.
  • Role in Skin Health: It has been studied for its protective effects against UV radiation, highlighting its potential use in skincare formulations aimed at preventing skin aging.
  • Research Potential: Ongoing studies are focusing on its potential role in neuroprotection, indicating that it may help in mitigating the effects of neurodegenerative diseases.

In summary, 2-(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)acetic acid is more than just a compound; it represents a bridge between antioxidant research and practical health applications. As scientists continue to explore its benefits, it serves as a reminder of the intricate relationship between chemical structures and biological functions.

Synonyms
6-hydroxy-2,5,7,8-tetramethylchroman-2-acetic acid
SCHEMBL6028036
IETSMPQISKAPQX-UHFFFAOYSA-N
(+/-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-acetic acid
(+/-) -(6-hydroxy-2,5,7,8- tetramethylchroman-2-yl) acetic acid
(+/-) -(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)acetic acid
(+/-)-(6-hydroxy-2,5, 7,8-tetramethylchroman-2-yl) acetic acid
(+/-)-(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)acetic acid
(+/-)-(6hydroxy-2,5,7,8-tetramethylchroman-2-yl) acetic acid
2-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)acetic acid, AldrichCPR
rac.-(6-hydroxy-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)acetic acid