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Vidarabine

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Identification
Molecular formula
C10H13N5O4
CAS number
5536-17-4
IUPAC name
2-(6-anilinopurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
State
State

At room temperature, vidarabine is in a solid state, typically available as a crystalline powder.

Melting point (Celsius)
260.00
Melting point (Kelvin)
533.15
Boiling point (Celsius)
788.15
Boiling point (Kelvin)
1 061.30
General information
Molecular weight
267.24g/mol
Molar mass
267.2410g/mol
Density
1.6640g/cm3
Appearence

Vidarabine is a white to off-white crystalline powder. It tends to absorb moisture from the air, making it slightly hygroscopic. It is odorless and has a bitter taste.

Comment on solubility

Solubility of 2-(6-anilinopurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

The compound 2-(6-anilinopurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, with the molecular formula C10H13N5O4, presents unique solubility characteristics that are influenced by its chemical structure. Understanding the solubility of this compound can be quite useful in various applications.

Key Points on Solubility

  • Polarity: The presence of multiple functional groups, particularly hydroxyl (-OH) groups, suggests that this compound may exhibit moderate to good solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the hydroxymethyl group may enhance its solubility in aqueous environments.
  • Organic Solvents: It may also show varying solubility in organic solvents, such as alcohols or dimethyl sulfoxide (DMSO), which can interact well with the compound's functional groups.

Moreover, the solubility behavior can depend on factors such as temperature, pH, and the presence of salts or other solutes. The general consensus in the field is that **“the solubility of a compound is a critical property that defines its usability in pharmaceutical formulations and biochemical applications.”**

In conclusion, while specific experimental data might still be necessary for precise solubility values, the various functional groups indicate a potential for significant solubility in both polar and semi-polar solvents, making this compound versatile for further studies or applications.

Interesting facts

Interesting Facts about 2-(6-anilinopurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

This compound is known for its intriguing combination of structural features and biological significance, making it a subject of interest in both chemistry and pharmacology. Below are some noteworthy points regarding this unique compound:

  • Complex Structure: The compound exhibits a multifaceted structure with a purine base attached to a tetrahydrofuran ring. This combination enhances its potential for interactions with various biological targets.
  • Biological Relevance: As derivatives of purines often play critical roles in biological systems, this compound can possibly mimic or interfere with nucleobases, potentially impacting cellular processes, especially in relation to nucleic acid metabolism.
  • Potential Therapeutic Applications: Compounds like this one are investigated for their roles in drug development, particularly in treating diseases such as cancer, where manipulating nucleic acid pathways can prove advantageous.
  • Research Value: Its structural characteristics make it a valuable candidate for research within medicinal chemistry, where understanding how small changes in structure can influence biological activity is key.
  • Multifunctionality: The presence of both an amino group and a hydroxymethyl group suggests opportunities for further functionalization, which could lead to the development of more effective derivatives with enhanced properties.

Overall, 2-(6-anilinopurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol serves as an excellent example of how organic chemistry can intersect with biological science, opening doors for innovative therapeutic solutions. In the words of a prominent researcher in the field, "The true power of chemistry lies in its ability to unveil the unseen connections within life itself."

Synonyms
ADENOSINE,6N-PHENYL
DTXSID00874788
NSC337772
SCHEMBL16092854
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(phenylamino)-9H-purin-9-yl]oxolane-3,4-diol
DTXCID401012913
HMS3374H06
NSC517192
NSC-337772
NSC-517192