Skip to main content

Vidarabine

ADVERTISEMENT
Identification
Molecular formula
C10H13N5O4S
CAS number
24356-66-9
IUPAC name
2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)tetrahydrofuran-3,4-diol
State
State

Vidarabine is typically in a solid state at room temperature and is often found in powdered form.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.00
Boiling point (Celsius)
570.00
Boiling point (Kelvin)
843.00
General information
Molecular weight
285.28g/mol
Molar mass
285.2760g/mol
Density
3.2605g/cm3
Appearence

Vidarabine typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)tetrahydrofuran-3,4-diol

The solubility of 2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)tetrahydrofuran-3,4-diol (C10H13N5O4S) presents interesting characteristics due to its complex structure. Several factors influence its solubility:

  • Polarity: The presence of multiple functional groups, such as amino and hydroxy groups, enhances the compound's polarity. This can increase its solubility in polar solvents like water.
  • Hydrogen Bonding: The hydroxyl (-OH) groups can form hydrogen bonds with solvent molecules, which often leads to increased solubility.
  • Aliphatic and Aromatic Character: The tetrahydrofuran ring contributes to some non-polar characteristics, which might limit solubility in purely polar solvents.
  • Sulfanyl Group: The methylsulfanyl functional group may also influence its interaction with different solvents, possibly enhancing solubility in organic solvents.

In summary, while this compound may exhibit a degree of solubility in polar solvents due to its polar functional groups, its overall solubility profile would need to be determined through experimental methods to understand its behavior in various solvents fully.

Interesting facts

Interesting Facts about 2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)tetrahydrofuran-3,4-diol

This intriguing compound belongs to the class of molecules known as nucleoside analogs, which mimic the natural nucleosides found in DNA and RNA. Its structure is characterized by the presence of both purine and tetrahydrofuran moieties, making it a compound of considerable interest in biochemical research.

Key Attributes

  • Biological Relevance: The inclusion of the 6-aminopurin moiety suggests potential interactions with cellular mechanisms, particularly those related to nucleic acid synthesis and repair processes.
  • Pharmaceutical Potential: Nucleoside analogs have a history of use in antiviral and anticancer drugs. This compound may exhibit similar therapeutic properties, warranting further investigation.
  • Mechanistic Studies: Understanding its interactions with enzymes can provide insights into DNA polymerase function and the development of resistance to antiviral therapies.
  • Structure-Activity Relationship: Examining how structural modifications influence biological activity could lead to the design of more effective drugs.

As researchers delve into the properties of 2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)tetrahydrofuran-3,4-diol, quotes from notable chemists emphasize the importance of nucleoside analog research: “Understanding the nuances of these compounds can unlock vast therapeutic potentials.”

In summary, this compound is more than just an interesting chemical structure; it represents a vital step toward developing new treatments for diseases linked to nucleic acid metabolism. Ongoing research holds promise for innovative applications in medicine.

Synonyms
2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol
2457-81-0
beta-D-Ribofuranose, 1-(6-amino-9H-purin-9-yl)-1-deoxy-5-S-methyl-5-thio-
53458-29-0
5'-CH3S-xyloA
(+/-)-p-ethoxybenzoin
.beta.-D-Ribofuranose, 1-(6-amino-9H-purin-9-yl)-1-deoxy-5-S-methyl-5-thio-
9-(5-s-methyl-5-thiopentofuranosyl)-9h-purin-6-amine
Adenosine + C2H5S
SCHEMBL890628
DTXSID70862955
CHEBI:180963
5\'-S-methyl-5\'-thioadenosine
9-(5'-Deoxy-5'-(methylthio)-beta-D-xylofuranosyl)-adenine
NSC166536
NSC166540
NSC208835
NSC335422
AKOS024285973
NSC-166536
NSC-166540
NSC-208835
NCGC00263645-01
NCGC00263645-02
5'-Deoxy-5'-(methylthio)adenosine, 97%
2-(6-aminopurin-9-yl)-5-(methylsulanylmethyl)oxolane-3,4-diol
(2R,5S)-2-(6-Aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol
53458-31-4