Skip to main content

Vidarabine

ADVERTISEMENT
Identification
Molecular formula
C10H13N5O4
CAS number
5536-17-4
IUPAC name
2-(6-aminopurin-9-yl)-5-methyl-tetrahydrofuran-3,4-diol
State
State

At room temperature, Vidarabine is in solid state, typically in lyophilized powder form.

Melting point (Celsius)
257.00
Melting point (Kelvin)
530.15
Boiling point (Celsius)
679.20
Boiling point (Kelvin)
952.35
General information
Molecular weight
267.27g/mol
Molar mass
267.2690g/mol
Density
2.0200g/cm3
Appearence

Vidarabine is a white or almost white crystalline powder. It is known for its characteristic crystalline texture.

Comment on solubility

Solubility of 2-(6-aminopurin-9-yl)-5-methyl-tetrahydrofuran-3,4-diol (C10H13N5O4)

The solubility of 2-(6-aminopurin-9-yl)-5-methyl-tetrahydrofuran-3,4-diol is an interesting subject due to its complex structure and the presence of various functional groups. Understanding its solubility is crucial for applications in pharmaceuticals and biochemistry where it may serve as a biologically active compound. Here are some key considerations:

  • Polarity: The presence of nitrogen and hydroxyl groups contributes to polarity, which can enhance solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of this compound to form hydrogen bonds may improve its solubility in aqueous environments.
  • Solvent Compatibility: It may exhibit varying solubilities depending on the solvent used; for instance, it is likely more soluble in dimethyl sulfoxide (DMSO) or methanol than in non-polar solvents like hexane.
  • pH Dependence: The solubility may change with pH levels due to the ionization of amino and hydroxyl groups, thus making understanding its behavior in different pH conditions essential.

Overall, the solubility characteristics of this compound can be summarized as influenced by several factors such as polymorphism, intermolecular interactions, and the nature of the solvent. This multi-faceted solubility profile highlights the importance of context-dependent factors that determine how readily the compound dissolves.

Interesting facts

Discovering 2-(6-aminopurin-9-yl)-5-methyl-tetrahydrofuran-3,4-diol

This intriguing compound, known as 2-(6-aminopurin-9-yl)-5-methyl-tetrahydrofuran-3,4-diol, represents a unique intersection of organic chemistry and biochemistry. With its structure featuring both the purine base and a tetrahydrofuran ring, it stands out for several reasons:

  • Biological Relevance: The compound's purine base, derived from nucleobases like adenine and guanine, places it firmly within the scope of molecular biology. Purines are critical components of DNA and RNA, and their derivatives often play essential roles in physiological processes.
  • Potential Therapeutic Applications: Research has suggested that similar compounds may exhibit antiviral and anticancer activities. Chemists are actively exploring the medicinal potential of modified purines.
  • Versatile Synthetic Pathways: The preparation of this compound involves intriguing synthesis methods that showcase the creativity and skill of chemists. The ability to manipulate the tetrahydrofuran unit enhances possibilities for developing new derivatives with tailored properties.
  • Intramolecular Interactions: The unique structure also opens avenues for studying the interactions within the compound itself or with other biomolecules, providing insight into its stability and reactivity.

In the words of a renowned chemist, "The beauty of chemistry lies not just in the compounds themselves but in the intricate dance of atoms and molecules that dictate their function." Exploring compounds like 2-(6-aminopurin-9-yl)-5-methyl-tetrahydrofuran-3,4-diol exemplifies this principle, inviting future researchers to unlock its secrets and applications.


Synonyms
72-90-2
9H-Purin-6-amine, 9-(5-deoxy-.alpha.-D-xylofuranosyl)-
5\'-deoxyadenosine
Compound NP-015368
SCHEMBL12453581
1H-Purin-6-amine,9-(5-deoxy-b-D-xylofuranosyl)- (9CI)
DTXSID30863448
NSC86102
NSC89222
BDBM50031233
NSC-86102
NSC-89222
NSC102642
PDSP1_001034
PDSP2_001018
AKOS040738757
NSC-102642
55670-08-1
PD093867
9-(5-deoxypentofuranosyl)-9H-purin-6-amine
2-(6-Amino-purin-9-yl)-5-methyl-tetrahydro-furan-3,4-diol
4152-76-5