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Tenofovir

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Identification
Molecular formula
C9H14N5O4
CAS number
147127-20-6
IUPAC name
2-(6-aminopurin-9-yl)-2-(hydroxymethyl)-5-methylene-tetrahydrofuran-3,4-diol
State
State

Tenofovir is in solid state at room temperature, usually as a white crystalline powder.

Melting point (Celsius)
279.00
Melting point (Kelvin)
552.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
287.21g/mol
Molar mass
287.2130g/mol
Density
1.5000g/cm3
Appearence

Tenofovir typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(6-aminopurin-9-yl)-2-(hydroxymethyl)-5-methylene-tetrahydrofuran-3,4-diol

The solubility of the compound 2-(6-aminopurin-9-yl)-2-(hydroxymethyl)-5-methylene-tetrahydrofuran-3,4-diol, with the chemical formula C9H14N5O4, can be influenced by various factors such as temperature, pH, and the presence of other solutes. This compound, predominantly composed of nitrogen and hydroxyl groups, suggests the following insights into its solubility characteristics:

  • Hydrophilicity: The presence of multiple hydroxyl groups in the structure typically enhances solubility in polar solvents such as water.
  • pH Dependency: Certain compounds may exhibit altered solubility profiles at different pH levels; therefore, acidic or basic conditions can impact its dissolution.
  • Temperature Influence: Increased temperatures generally lead to higher solubility for many organic compounds, making thermal adjustments a useful strategy.
  • Interactions with Solvents: Non-polar solvents may solubilize this compound to a lesser extent, whereas polar solvents are likely more effective.

In summary, while the solubility of this compound may seem favorable in polar environments, it is vital to consider the conditions under which solubility is assessed. As chemists often say, "Like dissolves like", highlighting the importance of matching solvant polarity to optimize dissolution processes.

Interesting facts

Interesting Facts about 2-(6-aminopurin-9-yl)-2-(hydroxymethyl)-5-methylene-tetrahydrofuran-3,4-diol

This compound, often referred to as a nucleotide analog, has piqued the interest of many in the fields of biochemistry and medicinal chemistry. Here are some captivating details about this intriguing molecule:

  • Structure and Function: The compound features a unique tetrahydrofuran ring which contributes to its structural complexity. Its design facilitates interaction with biological macromolecules, mimicking natural nucleotides.
  • Biological Importance: Compounds like this one play pivotal roles in cellular processes, particularly in DNA and RNA synthesis. Understanding their mechanisms can lead to advances in genetic research and biotechnology.
  • Pharmaceutical Applications: As a nucleotide analog, this compound has potential therapeutic applications in antiviral and anticancer treatments, highlighting the ongoing search for effective drugs targeting nucleic acid metabolism.
  • Research Insights: By studying this compound, scientists aim to elucidate the roles of nucleotides in various biological pathways, helping uncover the intricacies of cellular function and disease mechanisms.
  • Encourages Innovation: The synthesis and characterization of such complex compounds drive innovation in synthetic organic chemistry, challenging researchers to develop novel methodologies and techniques.

In summary, 2-(6-aminopurin-9-yl)-2-(hydroxymethyl)-5-methylene-tetrahydrofuran-3,4-diol is more than just a compound; it offers a gateway to understanding the intricacies of life at a molecular level and holds promise in the therapeutic arena. As scientists continually explore its potential, we are reminded of the beauty and complexity of chemical biology.

Synonyms
Angustmycin A
UPCMLD-DP098
CBiol_001975
KBioGR_000329
KBioSS_000329
CHEMBL2360461
SCHEMBL22430502
UPCMLD-DP098:001
UPCMLD-DP098:002
KBio2_000329
KBio2_002897
KBio2_005465
KBio3_000657
KBio3_000658
Bio1_000261
Bio1_000750
Bio1_001239
Bio2_000325
Bio2_000805
HMS1362A11
BCP30193
IDI1_002080
SMP2_000077
NCGC00161649-01
NCGC00161649-02
Antibiotic A 14;Decoyinine;U 7984;U-7984;U7984;A 14