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Pentamidine

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Identification
Molecular formula
C19H24Cl2N4
CAS number
100-33-4
IUPAC name
2-[6-[[amino-[[amino-(4-chloroanilino)methylene]amino]methylene]amino]hexyl]-1-[amino-(4-chloroanilino)methylene]guanidine
State
State

Pentamidine is typically in a solid state at room temperature. It appears as a white to off-white crystalline powder.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
596.40
Boiling point (Kelvin)
869.60
General information
Molecular weight
340.33g/mol
Molar mass
340.2140g/mol
Density
1.0050g/cm3
Appearence

Pentamidine is an odorless, crystalline white solid that may appear as a white or off-white powder depending on its purity and processing.

Comment on solubility

Solubility of 2-[6-[[amino-[[amino-(4-chloroanilino)methylene]amino]methylene]amino]hexyl]-1-[amino-(4-chloroanilino)methylene]guanidine (C19H24Cl2N4)

The solubility of this compound can be influenced by various factors, primarily due to its complex structure containing both hydrophilic and hydrophobic regions. Below are some important considerations regarding its solubility:

  • Structural Composition: The presence of amino groups suggests potential for strong interactions with water, while the chloroanilino moieties may contribute to hydrophobic characteristics.
  • Polarity: The compound's overall polarity will dictate its solubility in different solvents. An increase in polar functional groups typically enhances solubility in polar solvents.
  • pH Influence: The compound could behave differently in varying pH conditions due to the amino groups, which can accept or donate protons, altering solubility.
  • Temperature Effects: As with many compounds, temperature increases generally lead to increased solubility. However, this relationship can vary depending on the solvent.
  • Solvent Choice: This compound may exhibit good solubility in polar organic solvents, but limited solubility in non-polar solvents.

In summary, while the solubility of C19H24Cl2N4 can be substantial depending on conditions, the specific balance of its functional groups and overall molecular structure makes it unique. Therefore, studying its solubility profile in various environments is crucial for understanding its potential applications.

Interesting facts

Interesting Facts about 2-[6-[[amino-[[amino-(4-chloroanilino)methylene]amino]methylene]amino]hexyl]-1-[amino-(4-chloroanilino)methylene]guanidine

This complex compound is part of a fascinating class of organic molecules that exhibit significant biological activity, making it of great interest in medicinal chemistry. Here are some notable aspects:

  • Multi-functional Structure: The compound contains multiple amino groups along with a guanidine moiety, illustrating the complexity of its structure. This multifaceted setup can potentially allow for diverse interactions with biological targets.
  • Potential Therapeutic Uses: Compounds like this one are often explored for their potential in drug development, particularly for conditions requiring modulation of biological pathways through enzymatic inhibition or receptor interaction.
  • Chlorinated Aromatic Influence: The presence of 4-chloroanilino groups may enhance the lipophilicity of the compound, impacting its absorption and distribution within biological systems, which is crucial for effectiveness as a therapeutic agent.
  • Guanidine Significance: Guanidine derivatives are known for their role in various pharmacological activities, including antihypertensive, antidiabetic, and even antimicrobial properties.
  • Research Applications: Beyond pharmacology, compounds like this may serve as valuable probes in biochemical research, aiding in the understanding of complex biological networks and interactions.

As a chemistry student or researcher, exploring the potential impacts of such compounds not only enhances your understanding of organic chemistry but also opens doors to innovations in medical science. In the words of a famous chemist, “Understanding the structure function relationship in compounds is key to unearthing new therapeutic avenues.”

With its intricate design, this compound reflects the beauty and complexity of chemical science, paving the way for discoveries that might someday lead to significant advancements in treatment methodologies.

Synonyms
55-56-1
Nolvasan
MFCD00009673
Chlorhexidine Base
2-[6-[[amino-[[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
Epitope ID:115577
HMS3373P16
AKOS026749998
FB37204
NCGC00016246-12
Bis(5-(p-chlorophenyl)biguanidinio)hexane
SY066631
NS00003107
D78200
Q15646788