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Vidarabine

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Identification
Molecular formula
C10H13N5O4
CAS number
5536-17-4
IUPAC name
2-(6-amino-2-anilino-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
State
State

At room temperature, Vidarabine is in a solid state, specifically a crystalline powder.

Melting point (Celsius)
260.50
Melting point (Kelvin)
533.65
Boiling point (Celsius)
140.00
Boiling point (Kelvin)
413.15
General information
Molecular weight
267.27g/mol
Molar mass
267.2670g/mol
Density
1.6603g/cm3
Appearence

Vidarabine appears as a white to almost white crystalline powder. It is known for its slight solubility in water and alcohol. The compound is generally stable under normal conditions and is sensitive to light, which may induce degradation.

Comment on solubility

Solubility of 2-(6-amino-2-anilino-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

The compound 2-(6-amino-2-anilino-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, with the chemical formula C10H13N5O4, presents intriguing characteristics regarding its solubility.

Key Points on Solubility:

  • Polarity: Due to the presence of multiple functional groups, including amino and hydroxymethyl groups, the compound exhibits a notable degree of polarity.
  • Solvent Compatibility: It is expected to be soluble in polar solvents such as water and methanol, making it suitable for various biochemical and pharmaceutical applications.
  • Hydrogen Bonding: The hydroxymethyl group increases the potential for hydrogen bonding, further enhancing solubility in aqueous environments.
  • pH Dependency: The solubility may be affected by the pH of the solution, which can alter the ionization states of the functional groups, thus impacting overall solubility.

In summary, while generalizations can be made, the solubility of this compound is influenced by a complex interplay of its functional groups, molecular interactions, and environmental conditions. As always, experimental validation is essential to ascertain precise solubility characteristics.

Interesting facts

Interesting Facts about 2-(6-amino-2-anilino-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

This intriguing compound, often referred to as a derivative of purine, plays a crucial role in several biochemical applications. Here are some captivating aspects of this compound:

  • Structural Complexity: The compound showcases a multifaceted structure featuring both anilino and hydroxymethyl groups, which contribute to its diverse reactivity and biological activity.
  • Biological Relevance: As a purine derivative, it is related to essential cellular processes such as nucleotide synthesis and DNA/RNA metabolism. Compounds in this class often have implications in pharmacology.
  • Potential Therapeutic Uses: Research has indicated that derivatives of this compound may exhibit potential as antiviral or anticancer agents, due to their ability to interfere with nucleic acid synthesis.
  • Research Interest: In scientific literature, compounds like this one are frequently studied for their role in developing new therapeutic agents, particularly in targeting cellular mechanisms related to disease.
  • Modification and Synthesis: The synthesis of this compound involves several chemical reactions where subtle changes can lead to significant differences in activity, making it a focal point for synthetic organic chemistry.

To quote a notable chemist, "The beauty of chemistry lies in the structure and function; understanding how each part interacts is key to unlocking its potential." This compound serves as a perfect example of that principle, representing a bridge between abstraction and application in pharmaceutical sciences.

Overall, 2-(6-amino-2-anilino-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is not just a chemical formula—it is a gateway to understanding important biological processes and developing innovative medicinal therapies.

Synonyms
2-(6-amino-2-anilino-9-purinyl)-5-(hydroxymethyl)oxolane-3,4-diol
CHEBI:91804
DTXSID50866310
SCNILGOVBBRMBK-UHFFFAOYSA-N
HMS3268A18
L000209
6-amino-2-phenylamino-9-b-D-ribofuranosyl-9H-purine
9-Pentofuranosyl-N~2~-phenyl-9H-purine-2,6-diamine
BRD-A64933752-001-01-0
Q27163604
6-amino-2-phenylamino-9-beta-delta-ribofuranosyl-9H-purine
2-[6-amino-2-(phenylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
(2S,3S,4R,5S)-2-(6-amino-2-(phenylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol