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Meldrum's acid

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Identification
Molecular formula
C6H6O4
CAS number
2033-24-1
IUPAC name
2-(5-oxo-2-furylidene)acetic acid
State
State

Meldrum's acid is typically found in the solid state at room temperature. It is a stable compound commonly used in organic synthesis and can be handled with standard laboratory techniques.

Melting point (Celsius)
94.50
Melting point (Kelvin)
367.65
Boiling point (Celsius)
309.60
Boiling point (Kelvin)
582.75
General information
Molecular weight
158.12g/mol
Molar mass
158.1340g/mol
Density
1.6011g/cm3
Appearence

Meldrum's acid appears as a white crystalline solid. It is known for its high purity and can form sharp crystal structures. It is stable under ordinary conditions but should be stored properly to prevent degradation.

Comment on solubility

Solubility of 2-(5-oxo-2-furylidene)acetic acid (C6H6O4)

The solubility of 2-(5-oxo-2-furylidene)acetic acid is an intriguing aspect of this compound that can significantly impact its applications in various fields. This acid exhibits moderate solubility characteristics, influenced by its polar functional groups. Here are some key points regarding its solubility:

  • Polarity: The presence of both a carboxylic acid group and a carbonyl group contributes to the overall polarity of the molecule, enhancing its interaction with polar solvents.
  • Aqueous Solubility: 2-(5-oxo-2-furylidene)acetic acid is generally soluble in water, making it suitable for various biological and chemical applications.
  • Solvent Compatibility: It displays better solubility in polar organic solvents such as methanol and ethanol, yet may have limited solubility in non-polar solvents.
  • Temperature Dependence: Like many organic acids, solubility may increase with temperature, highlighting the importance of conditions in handling this compound.

In conclusion, understanding the solubility of 2-(5-oxo-2-furylidene)acetic acid is crucial for its effective use in research and industry, as well as for predicting its behavior in various chemical environments. The compound's ability to dissolve in polar media allows for its application in reactions, particularly in the synthesis of other chemical species.

Interesting facts

Exploring 2-(5-oxo-2-furylidene)acetic Acid

2-(5-oxo-2-furylidene)acetic acid is a fascinating compound that has captured the attention of researchers and chemists alike due to its unique structure and potential applications. Here are some interesting insights about this compound:

  • Structural Features: The compound contains a furan ring, which contributes to its aromatic properties. The presence of the 5-oxo group enhances its biological activity, making it an intriguing subject for pharmacological studies.
  • Biological Activity: Compounds like 2-(5-oxo-2-furylidene)acetic acid are often investigated for their potential anti-inflammatory and analgesic effects. Research indicates that the furan moiety is crucial for the activity of various drugs, thus highlighting its significance in medicinal chemistry.
  • Synthesis Opportunities: The synthesis of 2-(5-oxo-2-furylidene)acetic acid can be achieved through several methods, often involving the condensation of furan derivatives with acetic acid. This versatility in synthesis can lead to novel derivatives with enhanced properties.
  • Potential Applications: Due to its structural characteristics, the compound may find utility in:
    • Drug development, particularly in creating new therapeutic agents.
    • Material science, where derivatives could be explored for innovative applications.
  • Research Implications: The ongoing studies and modifications of 2-(5-oxo-2-furylidene)acetic acid could lead to breakthroughs in understanding how molecular structure influences biological function.

In conclusion, 2-(5-oxo-2-furylidene)acetic acid serves as an exciting example of how complex chemical structures can play a significant role in the fields of medicine and materials science, meriting further exploration and study.

Synonyms
2-(5-oxofuran-2-ylidene)acetic acid
4-carboxymethylenebut-2-en-4-olide
SCHEMBL2935896
DTXSID801278967
2-(5-Oxo-2(5H)-furanylidene)acetic acid
Q27108908